Comparison of urinary protein-to-creatinine ration, serum albumin, serum creatinine and systolic arterial blood pressure of glomerular injury cases in dogs with chronic kidney disease

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorVeterinary Pathologist-
Autor(es): dc.creatorSant'Anna, Paula Bilbau [UNESP]-
Autor(es): dc.creatorDa Silva Trindade, Fabricio-
Autor(es): dc.creatorGeraldes, Silvano Salgueiro [UNESP]-
Autor(es): dc.creatorDe Azevedo, Maria Gabriela Picelli [UNESP]-
Autor(es): dc.creatorHataka, Alessandre [UNESP]-
Autor(es): dc.creatorPaes, Antonio Carlos [UNESP]-
Autor(es): dc.creatorMelchert, Alessandra [UNESP]-
Autor(es): dc.creatorGuimaraes-Okamoto, Priscylla Tatiana Chalfun [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:51:24Z-
Data de disponibilização: dc.date.available2022-02-22T00:51:24Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.5433/1679-0359.2021v42n4p2339-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207783-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207783-
Descrição: dc.descriptionThis study aims at assessing the prevalence of glomerular alterations in dogs with chronic kidney disease (CKD) and comparing the clinical and laboratory parameters. The tests conducted include a double-blind histopathological assay conducted by two pathologists, urine tests including inactive sediment, urinary protein-to-creatinine (UPC), serum albumin and serum creatinine, as well as measurement of the systolic arterial blood pressure. The prevalence of glomerular injuries was determined and the predominant injury was compared with a group comprised of the remaining injuries. The study included 24 dogs with CKD. The results revealed a predominance of membranous glomerular alterations 17/24 (70, 83%), followed by glomerulosclerosis 3/24 (12, 50%), membranoproliferative injuries 2/24, glomerulocystic atrophy 1/24 and glomerular amyloidosis 1/24. Amyloidosis presented the highest UPC while the membranoproliferative injury presented the lowest mean concentration of serum albumin. Higher values in the UPC did not correspond with lower mean serum albumin values. Glomerulosclerosis presented the highest mean systolic blood pressure and glomerular atrophy presented the highest creatinine values. When comparing membranous injuries with a group comprised of the remaining injuries, the UPC did not present significant differences between the groups. Renal amyloidosis was included in the group with the lowest systolic arterial blood pressure values while membranoproliferative injury was included in the group with highest UPC. The group called others presented the highest creatinine value. Dogs with CKD may present several types of glomerular injuries with similar clinical and laboratory profiles. This study observed a predominance of membranous glomerular injuries, followed by membranoproliferative injuries, glomerulocystic atrophy and amyloidosis.-
Descrição: dc.descriptionVeterinary Medicine Program in School of Veterinary Medicine and Animal Sciences Universidade Estadual de São Paulo UNESP-
Descrição: dc.descriptionVeterinary Pathologist-
Descrição: dc.descriptionDepatment of Veterinary Clinic in School of Veterinary Medicine and Animal Sciences UNESP-
Descrição: dc.descriptionDepatment of Vet. Hygiene and Public Health in School of Veterinary Medicine and Animal Science UNESP-
Descrição: dc.descriptionVeterinary Medicine Program in School of Veterinary Medicine and Animal Sciences Universidade Estadual de São Paulo UNESP-
Descrição: dc.descriptionDepatment of Veterinary Clinic in School of Veterinary Medicine and Animal Sciences UNESP-
Descrição: dc.descriptionDepatment of Vet. Hygiene and Public Health in School of Veterinary Medicine and Animal Science UNESP-
Formato: dc.format2339-2358-
Idioma: dc.languageen-
Relação: dc.relationSemina:Ciencias Agrarias-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAmyloidosis-
Palavras-chave: dc.subjectDogs-
Palavras-chave: dc.subjectGlomerulocystic-
Palavras-chave: dc.subjectGlomerulopathy-
Palavras-chave: dc.subjectGlomerulus-
Título: dc.titleComparison of urinary protein-to-creatinine ration, serum albumin, serum creatinine and systolic arterial blood pressure of glomerular injury cases in dogs with chronic kidney disease-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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