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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Goethe University Frankfurt | - |
Autor(es): dc.contributor | CNRS/Lyon University | - |
Autor(es): dc.contributor | ETH Zurich | - |
Autor(es): dc.contributor | Fondazione Ri.MED | - |
Autor(es): dc.contributor | Federal University of Rio de Janeiro | - |
Autor(es): dc.contributor | Caxias Federal University of Rio de Janeiro | - |
Autor(es): dc.contributor | University of Wisconsin-Madison | - |
Autor(es): dc.contributor | University of California | - |
Autor(es): dc.contributor | NIDDK | - |
Autor(es): dc.contributor | IBS | - |
Autor(es): dc.contributor | Latvian Institute of Organic Synthesis | - |
Autor(es): dc.contributor | Leibniz University Hannover | - |
Autor(es): dc.contributor | Helmholtz Centre for Infection Research | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Buchmann Institute for Molecular Life Sciences | - |
Autor(es): dc.contributor | University of New Hampshire | - |
Autor(es): dc.contributor | University of Florence | - |
Autor(es): dc.contributor | University of Patras | - |
Autor(es): dc.contributor | Oswaldo Cruz Foundation (FIOCRUZ) | - |
Autor(es): dc.contributor | UConn Health | - |
Autor(es): dc.contributor | Signals GmbH Co. KG | - |
Autor(es): dc.contributor | Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) | - |
Autor(es): dc.contributor | Latvian Biomedical Research and Study Centre | - |
Autor(es): dc.contributor | Spanish National Research Council (CSIC) | - |
Autor(es): dc.contributor | Karlsruhe Institute of Technology | - |
Autor(es): dc.contributor | Technical University of Darmstadt | - |
Autor(es): dc.contributor | Martin Luther University Halle-Wittenberg | - |
Autor(es): dc.creator | Altincekic, Nadide | - |
Autor(es): dc.creator | Korn, Sophie Marianne | - |
Autor(es): dc.creator | Qureshi, Nusrat Shahin | - |
Autor(es): dc.creator | Dujardin, Marie | - |
Autor(es): dc.creator | Ninot-Pedrosa, Martí | - |
Autor(es): dc.creator | Abele, Rupert | - |
Autor(es): dc.creator | Abi Saad, Marie Jose | - |
Autor(es): dc.creator | Alfano, Caterina | - |
Autor(es): dc.creator | Almeida, Fabio C. L. | - |
Autor(es): dc.creator | Alshamleh, Islam | - |
Autor(es): dc.creator | de Amorim, Gisele Cardoso | - |
Autor(es): dc.creator | Anderson, Thomas K. | - |
Autor(es): dc.creator | Anobom, Cristiane D. | - |
Autor(es): dc.creator | Anorma, Chelsea | - |
Autor(es): dc.creator | Bains, Jasleen Kaur | - |
Autor(es): dc.creator | Bax, Adriaan | - |
Autor(es): dc.creator | Blackledge, Martin | - |
Autor(es): dc.creator | Blechar, Julius | - |
Autor(es): dc.creator | Böckmann, Anja | - |
Autor(es): dc.creator | Brigandat, Louis | - |
Autor(es): dc.creator | Bula, Anna | - |
Autor(es): dc.creator | Bütikofer, Matthias | - |
Autor(es): dc.creator | Camacho-Zarco, Aldo R. | - |
Autor(es): dc.creator | Carlomagno, Teresa | - |
Autor(es): dc.creator | Caruso, Icaro Putinhon [UNESP] | - |
Autor(es): dc.creator | Ceylan, Betül | - |
Autor(es): dc.creator | Chaikuad, Apirat | - |
Autor(es): dc.creator | Chu, Feixia | - |
Autor(es): dc.creator | Cole, Laura | - |
Autor(es): dc.creator | Crosby, Marquise G. | - |
Autor(es): dc.creator | de Jesus, Vanessa | - |
Autor(es): dc.creator | Dhamotharan, Karthikeyan | - |
Autor(es): dc.creator | Felli, Isabella C. | - |
Autor(es): dc.creator | Ferner, Jan | - |
Autor(es): dc.creator | Fleischmann, Yanick | - |
Autor(es): dc.creator | Fogeron, Marie-Laure | - |
Autor(es): dc.creator | Fourkiotis, Nikolaos K. | - |
Autor(es): dc.creator | Fuks, Christin | - |
Autor(es): dc.creator | Fürtig, Boris | - |
Autor(es): dc.creator | Gallo, Angelo | - |
Autor(es): dc.creator | Gande, Santosh L. | - |
Autor(es): dc.creator | Gerez, Juan Atilio | - |
Autor(es): dc.creator | Ghosh, Dhiman | - |
Autor(es): dc.creator | Gomes-Neto, Francisco | - |
Autor(es): dc.creator | Gorbatyuk, Oksana | - |
Autor(es): dc.creator | Guseva, Serafima | - |
Autor(es): dc.creator | Hacker, Carolin | - |
Autor(es): dc.creator | Häfner, Sabine | - |
Autor(es): dc.creator | Hao, Bing | - |
Autor(es): dc.creator | Hargittay, Bruno | - |
Autor(es): dc.creator | Henzler-Wildman, K. | - |
Autor(es): dc.creator | Hoch, Jeffrey C. | - |
Autor(es): dc.creator | Hohmann, Katharina F. | - |
Autor(es): dc.creator | Hutchison, Marie T. | - |
Autor(es): dc.creator | Jaudzems, Kristaps | - |
Autor(es): dc.creator | Jović, Katarina | - |
Autor(es): dc.creator | Kaderli, Janina | - |
Autor(es): dc.creator | Kalniņš, Gints | - |
Autor(es): dc.creator | Kaņepe, Iveta | - |
Autor(es): dc.creator | Kirchdoerfer, Robert N. | - |
Autor(es): dc.creator | Kirkpatrick, John | - |
Autor(es): dc.creator | Knapp, Stefan | - |
Autor(es): dc.creator | Krishnathas, Robin | - |
Autor(es): dc.creator | Kutz, Felicitas | - |
Autor(es): dc.creator | zur Lage, Susanne | - |
Autor(es): dc.creator | Lambertz, Roderick | - |
Autor(es): dc.creator | Lang, Andras | - |
Autor(es): dc.creator | Laurents, Douglas | - |
Autor(es): dc.creator | Lecoq, Lauriane | - |
Autor(es): dc.creator | Linhard, Verena | - |
Autor(es): dc.creator | Löhr, Frank | - |
Autor(es): dc.creator | Malki, Anas | - |
Autor(es): dc.creator | Bessa, Luiza Mamigonian | - |
Autor(es): dc.creator | Martin, Rachel W. | - |
Autor(es): dc.creator | Matzel, Tobias | - |
Autor(es): dc.creator | Maurin, Damien | - |
Autor(es): dc.creator | McNutt, Seth W. | - |
Autor(es): dc.creator | Mebus-Antunes, Nathane Cunha | - |
Autor(es): dc.creator | Meier, Beat H. | - |
Autor(es): dc.creator | Meiser, Nathalie | - |
Autor(es): dc.creator | Mompeán, Miguel | - |
Autor(es): dc.creator | Monaca, Elisa | - |
Autor(es): dc.creator | Montserret, Roland | - |
Autor(es): dc.creator | Mariño Perez, Laura | - |
Autor(es): dc.creator | Moser, Celine | - |
Autor(es): dc.creator | Muhle-Goll, Claudia | - |
Autor(es): dc.creator | Neves-Martins, Thais Cristtina | - |
Autor(es): dc.creator | Ni, Xiamonin | - |
Autor(es): dc.creator | Norton-Baker, Brenna | - |
Autor(es): dc.creator | Pierattelli, Roberta | - |
Autor(es): dc.creator | Pontoriero, Letizia | - |
Autor(es): dc.creator | Pustovalova, Yulia | - |
Autor(es): dc.creator | Ohlenschläger, Oliver | - |
Autor(es): dc.creator | Orts, Julien | - |
Autor(es): dc.creator | Da Poian, Andrea T. | - |
Autor(es): dc.creator | Pyper, Dennis J. | - |
Autor(es): dc.creator | Richter, Christian | - |
Autor(es): dc.creator | Riek, Roland | - |
Autor(es): dc.creator | Rienstra, Chad M. | - |
Autor(es): dc.creator | Robertson, Angus | - |
Autor(es): dc.creator | Pinheiro, Anderson S. | - |
Autor(es): dc.creator | Sabbatella, Raffaele | - |
Autor(es): dc.creator | Salvi, Nicola | - |
Autor(es): dc.creator | Saxena, Krishna | - |
Autor(es): dc.creator | Schulte, Linda | - |
Autor(es): dc.creator | Schiavina, Marco | - |
Autor(es): dc.creator | Schwalbe, Harald | - |
Autor(es): dc.creator | Silber, Mara | - |
Autor(es): dc.creator | Almeida, Marcius da Silva | - |
Autor(es): dc.creator | Sprague-Piercy, Marc A. | - |
Autor(es): dc.creator | Spyroulias, Georgios A. | - |
Autor(es): dc.creator | Sreeramulu, Sridhar | - |
Autor(es): dc.creator | Tants, Jan-Niklas | - |
Autor(es): dc.creator | Tārs, Kaspars | - |
Autor(es): dc.creator | Torres, Felix | - |
Autor(es): dc.creator | Töws, Sabrina | - |
Autor(es): dc.creator | Treviño, Miguel Á. | - |
Autor(es): dc.creator | Trucks, Sven | - |
Autor(es): dc.creator | Tsika, Aikaterini C. | - |
Autor(es): dc.creator | Varga, Krisztina | - |
Autor(es): dc.creator | Wang, Ying | - |
Autor(es): dc.creator | Weber, Marco E. | - |
Autor(es): dc.creator | Weigand, Julia E. | - |
Autor(es): dc.creator | Wiedemann, Christoph | - |
Autor(es): dc.creator | Wirmer-Bartoschek, Julia | - |
Autor(es): dc.creator | Wirtz Martin, Maria Alexandra | - |
Autor(es): dc.creator | Zehnder, Johannes | - |
Autor(es): dc.creator | Hengesbach, Martin | - |
Autor(es): dc.creator | Schlundt, Andreas | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:51:11Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:51:11Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-05-10 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.3389/fmolb.2021.653148 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207711 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207711 | - |
Descrição: dc.description | The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects. The international COVID19-NMR consortium seeks to provide such new approaches by gathering scientific expertise worldwide. In particular, making available viral proteins and RNAs will pave the way to understanding the SARS-CoV-2 molecular components in detail. The research in COVID19-NMR and the resources provided through the consortium are fully disclosed to accelerate access and exploitation. NMR investigations of the viral molecular components are designated to provide the essential basis for further work, including macromolecular interaction studies and high-throughput drug screening. Here, we present the extensive catalog of a holistic SARS-CoV-2 protein preparation approach based on the consortium’s collective efforts. We provide protocols for the large-scale production of more than 80% of all SARS-CoV-2 proteins or essential parts of them. Several of the proteins were produced in more than one laboratory, demonstrating the high interoperability between NMR groups worldwide. For the majority of proteins, we can produce isotope-labeled samples of HSQC-grade. Together with several NMR chemical shift assignments made publicly available on covid19-nmr.com, we here provide highly valuable resources for the production of SARS-CoV-2 proteins in isotope-labeled form. | - |
Descrição: dc.description | Institute for Organic Chemistry and Chemical Biology Goethe University Frankfurt | - |
Descrição: dc.description | Center of Biomolecular Magnetic Resonance (BMRZ) Goethe University Frankfurt | - |
Descrição: dc.description | Institute for Molecular Biosciences Goethe University Frankfurt | - |
Descrição: dc.description | Molecular Microbiology and Structural Biochemistry UMR 5086 CNRS/Lyon University | - |
Descrição: dc.description | Institute for Biochemistry Goethe University Frankfurt | - |
Descrição: dc.description | Swiss Federal Institute of Technology Laboratory of Physical Chemistry ETH Zurich | - |
Descrição: dc.description | Structural Biology and Biophysics Unit Fondazione Ri.MED | - |
Descrição: dc.description | National Center of Nuclear Magnetic Resonance (CNRMN CENABIO) Federal University of Rio de Janeiro | - |
Descrição: dc.description | Institute of Medical Biochemistry Federal University of Rio de Janeiro | - |
Descrição: dc.description | Multidisciplinary Center for Research in Biology (NUMPEX) Caxias Federal University of Rio de Janeiro, Campus Duque de | - |
Descrição: dc.description | Institute for Molecular Virology University of Wisconsin-Madison | - |
Descrição: dc.description | Institute of Chemistry Federal University of Rio de Janeiro | - |
Descrição: dc.description | Department of Chemistry University of California | - |
Descrição: dc.description | LCP NIDDK | - |
Descrição: dc.description | Univ. Grenoble Alpes CNRS CEA IBS | - |
Descrição: dc.description | Latvian Institute of Organic Synthesis | - |
Descrição: dc.description | BMWZ and Institute of Organic Chemistry Leibniz University Hannover | - |
Descrição: dc.description | Group of NMR-Based Structural Chemistry Helmholtz Centre for Infection Research | - |
Descrição: dc.description | Multiuser Center for Biomolecular Innovation (CMIB) Department of Physics São Paulo State University (UNESP) São José do Rio Preto | - |
Descrição: dc.description | Institute of Pharmaceutical Chemistry Goethe University Frankfurt | - |
Descrição: dc.description | Structural Genomics Consortium Buchmann Institute for Molecular Life Sciences | - |
Descrição: dc.description | Department of Molecular Cellular and Biomedical Sciences University of New Hampshire | - |
Descrição: dc.description | Department of Molecular Biology and Biochemistry University of California | - |
Descrição: dc.description | Magnetic Resonance Centre (CERM) University of Florence | - |
Descrição: dc.description | Department of Chemistry “Ugo Schiff” University of Florence | - |
Descrição: dc.description | Department of Pharmacy University of Patras | - |
Descrição: dc.description | Laboratory of Toxinology Oswaldo Cruz Foundation (FIOCRUZ) | - |
Descrição: dc.description | Department of Molecular Biology and Biophysics UConn Health | - |
Descrição: dc.description | Signals GmbH Co. KG | - |
Descrição: dc.description | Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) | - |
Descrição: dc.description | Latvian Biomedical Research and Study Centre | - |
Descrição: dc.description | Rocasolano” Institute for Physical Chemistry (IQFR) Spanish National Research Council (CSIC) | - |
Descrição: dc.description | Institute of Biophysical Chemistry Goethe University Frankfurt | - |
Descrição: dc.description | Karlsruhe Institute of Technology, IBG-4 | - |
Descrição: dc.description | Department of Biochemistry and National Magnetic Resonance Facility at Madison University of Wisconsin-Madison | - |
Descrição: dc.description | Department of Biology Technical University of Darmstadt | - |
Descrição: dc.description | Institute of Biochemistry and Biotechnology Charles Tanford Protein Centre Martin Luther University Halle-Wittenberg | - |
Descrição: dc.description | Multiuser Center for Biomolecular Innovation (CMIB) Department of Physics São Paulo State University (UNESP) São José do Rio Preto | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Frontiers in Molecular Biosciences | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | accessory proteins | - |
Palavras-chave: dc.subject | cell-free protein synthesis | - |
Palavras-chave: dc.subject | COVID-19 | - |
Palavras-chave: dc.subject | intrinsically disordered region | - |
Palavras-chave: dc.subject | NMR spectroscopy | - |
Palavras-chave: dc.subject | nonstructural proteins | - |
Palavras-chave: dc.subject | SARS-CoV-2 | - |
Palavras-chave: dc.subject | structural proteins | - |
Título: dc.title | Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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