A systematic review and meta-analysis of the effect of photodynamic therapy for the treatment of oral mucositis

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUNAERP - Department of Dentistry-
Autor(es): dc.creatorde Oliveira, Analú Barros [UNESP]-
Autor(es): dc.creatorFerrisse, Túlio Morandin [UNESP]-
Autor(es): dc.creatorBasso, Fernanda Gonçalves-
Autor(es): dc.creatorFontana, Carla Raquel [UNESP]-
Autor(es): dc.creatorGiro, Elisa Maria Aparecida [UNESP]-
Autor(es): dc.creatorBrighenti, Fernanda Lourenção [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:51:09Z-
Data de disponibilização: dc.date.available2022-02-22T00:51:09Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.pdpdt.2021.102316-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207706-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207706-
Descrição: dc.descriptionBackground: Oral mucositis is a significant reaction to antineoplastic treatment characterized with pain, nutritional compromise, impact on the quality of life, interruption in cancer therapy and risk for infection. There is no effective standard protocol for the treatment of oral mucositis. This study aims to synthesize the scientific evidence available about the effects of photodynamic therapy on treatment of oral mucositis. Methods: PubMed, Scopus, Web of Science, Science Direct, Scielo, Embase and Cochrane libraries were searched. Two independent and calibrated researchers (kappa = 0.92) performed all systematic steps according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). To access the risk of bias, RoB 2 and Delphi list criteria for clinical trials were used. Meta-analysis was conducted using the R software with “META” package. Results: Clinical and randomized clinical trials were included with a total of five articles. Meta-analysis, level of evidence, and risk of bias assessment were performed showing that photodynamic therapy was effective in reducing healing time in association with low-power laser therapy when compared to low-power laser therapy alone (p = 0.0005). Conclusion: Photodynamic therapy presents promising results for the treatment of oral mucositis. It may be an effective therapeutic option, contributing to the healing of injured tissues especially in the time needed for repair.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry - Department of Morphology Genetics Orthodontics and Pediatric Dentistry-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences - Department of Clinical Analysis-
Descrição: dc.descriptionUniversidade de Ribeirão Preto UNAERP - Department of Dentistry-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry - Department of Dental Materials and Prosthesis-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry - Department of Morphology Genetics Orthodontics and Pediatric Dentistry-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences - Department of Clinical Analysis-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry - Department of Dental Materials and Prosthesis-
Descrição: dc.descriptionFAPESP: 2018/18440-0-
Descrição: dc.descriptionFAPESP: 2018/23015-7-
Descrição: dc.descriptionFAPESP: 2019/08375-0-
Descrição: dc.descriptionFAPESP: 2020/07110-0-
Descrição: dc.descriptionFAPESP: 2021/01191-0-
Idioma: dc.languageen-
Relação: dc.relationPhotodiagnosis and Photodynamic Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectOral mucositis-
Palavras-chave: dc.subjectPhotodynamic therapy-
Palavras-chave: dc.subjectSystematic review, meta-analysis review-
Título: dc.titleA systematic review and meta-analysis of the effect of photodynamic therapy for the treatment of oral mucositis-
Aparece nas coleções:Repositório Institucional - Unesp

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