Global prevalence and molecular characterization of extended-spectrum β-lactamase producing-Escherichia coli in dogs and cats – A scoping review and meta-analysis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R)-
Autor(es): dc.contributorUniversidad Andres Bello-
Autor(es): dc.contributorPontificia Universidad Católica de Chile-
Autor(es): dc.creatorSalgado-Caxito, Marília [UNESP]-
Autor(es): dc.creatorBenavides, Julio A.-
Autor(es): dc.creatorAdell, Aiko D.-
Autor(es): dc.creatorPaes, Antonio Carlos [UNESP]-
Autor(es): dc.creatorMoreno-Switt, Andrea I.-
Data de aceite: dc.date.accessioned2022-02-22T00:50:52Z-
Data de disponibilização: dc.date.available2022-02-22T00:50:52Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.onehlt.2021.100236-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207622-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207622-
Descrição: dc.descriptionAntimicrobial resistance (AMR) represents a major threat to human and animal health. Part of the AMR dimension is the circulation of extended-spectrum β-lactamases producing-Escherichia coli (ESBL-E. coli), which is now commonly reported among companion animals. However, the global perspective of the prevalence and population structure of ESBL-E. coli circulating in dogs and cats has not been estimated limiting our understanding of their role in the dissemination of ESBL-E. coli. The aim of this study was to compare the prevalence of ESBL-E. coli between dogs and cats and across countries through meta-analysis. We also performed a scoping review to summarize the current knowledge on ESBL genes and E. coli clones circulating among companion animals. A total of 128 studies published in PubMed, Web of Science, and Scopus up to April 2020 were selected and contained information on prevalence and/or molecular characterization of ESBL genes and ESBL-E. coli clones. Our review shows an increase in the number of publications between 2000 and 2019, concentrated mainly in Europe. Prevalence varied across continents, ranging from 0.63% (Oceania) to 16.56% (Africa) in dogs and from 0% (Oceania) to 16.82% (Asia) in cats. Although there were twice as many studies reporting prevalence on dogs (n = 61) than on cats (n = 32), and only 9 studies focused exclusively on cats, our meta-analysis showed no difference in the global prevalence of ESBL-E. coli between dogs (6.87% [95% CI: 4.46–10.45%]) and cats (5.04% [95% CI: 2.42–10.22%]). A considerable diversity of ESBL genes (n = 60) and sequence types (ST) (n = 171) were recovered from companion animals. ESBL-E. coli encoded by CTX-M-15 (67.5%, 77/114) and SHV-12 (21.9%, 25/114), along with resistant strains of ST38 (22.7%, 15/66) and ST131 (50%, 33/66) were widespread and detected in all continents. While presence of ESBL-E. coli is widespread, the drivers influencing the observed ESBL-E. coli prevalence and the clinical relevance in veterinary medicine and public health along with economic impact of ESBL-E. coli infections among companion animals need to be further investigated.-
Descrição: dc.descriptionDepartment of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionMillennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R)-
Descrição: dc.descriptionDepartamento de Ecología y Biodiversidad Facultad de Ciencias de la Vida Universidad Andres Bello-
Descrição: dc.descriptionCentro de Investigación para la Sustentabilidad Facultad de Ciencias de la Vida Universidad Andres Bello-
Descrição: dc.descriptionEscuela de Medicina Veterinaria Universidad Andres Bello-
Descrição: dc.descriptionEscuela de Medicina Veterinaria Pontificia Universidad Católica de Chile-
Descrição: dc.descriptionDepartment of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationOne Health-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAntimicrobial resistance-
Palavras-chave: dc.subjectCompanion animals-
Palavras-chave: dc.subjectESBL-
Palavras-chave: dc.subjectPets-
Palavras-chave: dc.subjectResistance genes-
Palavras-chave: dc.subjectWorldwide-
Título: dc.titleGlobal prevalence and molecular characterization of extended-spectrum β-lactamase producing-Escherichia coli in dogs and cats – A scoping review and meta-analysis-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.