Metastatic calcification and granulomatous grastroenteritis associated to Pythium insidiosum in a dog

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorManço, Micaela Honorato [UNESP]-
Autor(es): dc.creatorFerreira, Suellen Karoline [UNESP]-
Autor(es): dc.creatorPerossi, Isabela Fernanda Spinelli [UNESP]-
Autor(es): dc.creatorKlein, Mariana [UNESP]-
Autor(es): dc.creatorPelógia, Marina Emanoella Seruti [UNESP]-
Autor(es): dc.creatorCarra, Gabriel João Unger [UNESP]-
Autor(es): dc.creatorDe Souza, Camila Dezembro Dutra [UNESP]-
Autor(es): dc.creatorCosta, Mirela Tinucci [UNESP]-
Autor(es): dc.creatorBosco, Sandra De Moraes Gimenes [UNESP]-
Autor(es): dc.creatorMoraes, Paola Castro [UNESP]-
Autor(es): dc.creatorVasconcelos, Rosemeri De Oliveira [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:50:48Z-
Data de disponibilização: dc.date.available2022-02-22T00:50:48Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.24070/bjvp.1983-0246.v14i1p50-55-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207600-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207600-
Descrição: dc.descriptionPythiosis is a granulomatous process of which the oomycete Pythium insidiosum is its etiological agent. It can affect animals and humans alike and its infection occurs when free zoospores in the water get in contact with the target tissues and encyst. The disease often occurs in tropical places with abundance of water and aquatic plants that host the fungus. Dogs infection is predominantly gastric with granuloma formations in the stomach and intestine with progressive signs of vomiting, weight loss and diarrhea. In this case report, we described clinical, surgical, necroscopic and histopathological findings of a one year and two months old, male boxer that presented clinical signs of anorexia and persistent vomiting. It was noticed on ultrasound examination an increase in stomach and intestine thickness. Laparotomy confirmed a mass affecting the gastric wall which, an incision biopsy, showed an abundant fibrous tissue associated with granulomatous reaction that was surrounded by tubuliform structures. Due to clinical complications, euthanasia was performed and in necroscopic examination a markedly increased stomach and duodenum was observed. An; histological examination of this areas it was observed that they contained granulation tissue with giant cells and epithelioids macrophages around necrosed areas associated with lymphocytes infiltrate. Also, it was possible to observe tubuliform structures by the Grocott-Gomori’s Methenamine Silver (GMS) stain, this finding is compatible with the agent Pythium insidiosum. Therefore, this presumptive identification was confirmed by PCR analysis which amplicon had 97.83% similarity with current available genomic sequence of P. insidiosum.-
Descrição: dc.descriptionDepartment of Veterinary Pathology FCAV-UNESP-
Descrição: dc.descriptionDepartment of Veterinary Clinic and Surgery FCAV-UNESP-
Descrição: dc.descriptionInstitute of Biosciences Department of Microbiology and Immunology UNESP-
Descrição: dc.descriptionDepartment of Veterinary Pathology FCAV-UNESP-
Descrição: dc.descriptionDepartment of Veterinary Clinic and Surgery FCAV-UNESP-
Descrição: dc.descriptionInstitute of Biosciences Department of Microbiology and Immunology UNESP-
Formato: dc.format50-55-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Veterinary Pathology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDog-
Palavras-chave: dc.subjectGastric phytiosis-
Palavras-chave: dc.subjectGranuloma-
Palavras-chave: dc.subjectNecroscopic analysis-
Palavras-chave: dc.subjectOomycete-
Título: dc.titleMetastatic calcification and granulomatous grastroenteritis associated to Pythium insidiosum in a dog-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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