Modulation of the innate immune response, antioxidant system and oxidative stress during acute and chronic stress in pacu (Piaractus mesopotamicus)

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Londrina (UEL)-
Autor(es): dc.creatorde Fátima Pereira de Faria, Camila [UNESP]-
Autor(es): dc.creatordos Reis Martinez, Claudia Bueno-
Autor(es): dc.creatorTakahashi, Leonardo Susumu [UNESP]-
Autor(es): dc.creatorde Mello, Mariana Maluli Marinho [UNESP]-
Autor(es): dc.creatorMartins, Talísia Pereira [UNESP]-
Autor(es): dc.creatorUrbinati, Elisabeth Criscuolo [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:50:32Z-
Data de disponibilização: dc.date.available2022-02-22T00:50:32Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10695-021-00940-x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207537-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207537-
Descrição: dc.descriptionStress is an energy-demanding process, as well as the responses of the innate immune system, that impose a metabolic overload on cellular energy production, which can affect the cellular redox balance, causing oxidative damage. We evaluated the role of stress in the modulation of innate immune and oxidative/antioxidant mechanisms in juvenile pacu exposed to acute and chronic stressors. The experimental period lasted 30 days, and fish (113.7 ± 35.1 g) were fed commercial feed. During this period, half of the fish were not manipulated (Condition A), and the other half were chased with a dip net for 5 min twice a day (Condition C). After the 30-day period, fish from both groups were sampled (baseline sampling), and the remainders (not sampled) were air exposed for 3 min (acute stressor), returned to the tanks, and were sampled again 30 min, 3 h, 6 h, and 24 h after air exposure. We evaluated biomarkers of stress (circulating cortisol and glucose), the innate immune system (respiratory burst activity/RBA, hemolytic activity of the complement system (HA-AP) and serum concentration of lysozyme), oxidative damage (lipid peroxidation/LPO), and antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT; and glutathione peroxidase, GSH-Px). Our results showed that stress, acutely or chronically, caused a transient reduction of RAL and activated the HA-AP. Acutely, stress increased the lysozyme concentration. Furthermore, both conditions caused oxidative stress in the liver, and differently they modulated the antioxidant system, enhancing SOD activity and impairing CAT and GSH-Px activity.-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Centro de Aquicultura, Via de Acesso Paulo Donato Castellane, 14.884-900-
Descrição: dc.descriptionUniversidade Estadual de Londrina UEL Departamento de Ciências Fisiológicas, Rodovia Celso Garcia Cid - Pr 445 Km 380, Campus Universitário-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Faculdade de Ciências Agrárias e Tecnologia (FCAT-Unesp) Dracena, Rod. João Ribeiro de Barros, km 651-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Faculdade de Ciências Agrárias e Veterinárias, Via de Acesso Paulo Donato Castellane, 14-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Centro de Aquicultura, Via de Acesso Paulo Donato Castellane, 14.884-900-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Faculdade de Ciências Agrárias e Tecnologia (FCAT-Unesp) Dracena, Rod. João Ribeiro de Barros, km 651-
Descrição: dc.descriptionUniversidade Estadual Paulista UNESP Faculdade de Ciências Agrárias e Veterinárias, Via de Acesso Paulo Donato Castellane, 14-
Idioma: dc.languageen-
Relação: dc.relationFish Physiology and Biochemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCellular redox-
Palavras-chave: dc.subjectCortisol-
Palavras-chave: dc.subjectFish farming-
Palavras-chave: dc.subjectImmunity-
Palavras-chave: dc.subjectReactive oxygen species-
Título: dc.titleModulation of the innate immune response, antioxidant system and oxidative stress during acute and chronic stress in pacu (Piaractus mesopotamicus)-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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