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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual de Campinas (UNICAMP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Universidade Federal de Minas Gerais (UFMG) | - |
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Tiradentes University (UNIT) | - |
Autor(es): dc.creator | Cunha, John Lennon Silva | - |
Autor(es): dc.creator | Tomo, Saygo [UNESP] | - |
Autor(es): dc.creator | Mota, Carolina Peres | - |
Autor(es): dc.creator | Correia Neto, Ivan José | - |
Autor(es): dc.creator | de Sousa, Sílvia Ferreira | - |
Autor(es): dc.creator | León, Jorge Esquiche | - |
Autor(es): dc.creator | Albuquerque-Júnior, Ricardo Luiz Cavalcanti de | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:50:31Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:50:31Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.oraloncology.2021.105215 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207529 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207529 | - |
Descrição: dc.description | Pleomorphic lipomas are extremely rare in the oral cavity. Due to the significant overlap of morphological findings with several benign and malignant soft tissue tumors, especially in the absence of adipocytes, the diagnosis is challenging. We reported the clinicopathological and immunohistochemical features of an uncommon case of a fat-free variant of pleomorphic lipoma in a 48-year-old female presenting clinically as a painless nodule on the buccal mucosa. Microscopically, the lesion showed atypical spindle cells, numerous floret-like giant multinucleated cells, and abundant ropey collagen fibers bundles. Immunohistochemistry showed strong positivity for vimentin and CD34. Mast cell tryptase highlighted numerous mast cells distributed throughout all tumor stroma. S-100 protein, pan-cytokeratin, desmin, α-SMA, EMA, CD68, STAT6, Bcl-2, MDM2, and CDK4 were negative. Conservative surgical excision was carried out, and no recurrence was observed after 13 months of follow-up. Careful histopathological and immunohistochemistry analysis of these lesions is recommended to ensure the correct diagnosis and provide adequate management through a conservative surgical approach. To the best of our knowledge, this is the second case of fat-free pleomorphic lipoma in the oral cavity. | - |
Descrição: dc.description | Oral Pathology Section Department of Oral Diagnosis Piracicaba Dental School University of Campinas (UNICAMP) | - |
Descrição: dc.description | Oral Oncology Center São Paulo State University (UNESP) School of Dentistry | - |
Descrição: dc.description | Department of Oral Surgery and Pathology School of Dentistry Universidade Federal de Minas Gerais (UFMG) | - |
Descrição: dc.description | Department of Oral and Maxillofacial Pathology School of Dentistry University of São Paulo (USP) | - |
Descrição: dc.description | Oral Pathology Department of Stomatology Public Oral Health and Forensic Dentistry School of Dentistry of Ribeirão Preto University of São Paulo (USP) | - |
Descrição: dc.description | Laboratory of Morphology and Experimental Pathology Institute of Technology and Research Tiradentes University (UNIT) | - |
Descrição: dc.description | Oral Oncology Center São Paulo State University (UNESP) School of Dentistry | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Oral Oncology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Floret giant cells | - |
Palavras-chave: dc.subject | Lipoma | - |
Palavras-chave: dc.subject | Soft tissue neoplasm | - |
Título: dc.title | Fat-free pleomorphic lipoma of the buccal mucosa: An immunohistochemical study and literature review | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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