Effects of change in temperature on the cardiac contractility of broad-snouted caiman (Caiman latirostris) during digestion

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorLopes, André G. [UNESP]-
Autor(es): dc.creatorMonteiro, Diana A.-
Autor(es): dc.creatorKalinin, Ana L.-
Data de aceite: dc.date.accessioned2022-02-22T00:50:29Z-
Data de disponibilização: dc.date.available2022-02-22T00:50:29Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/jez.2457-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207517-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207517-
Descrição: dc.descriptionIn many reptiles, digestion has been associated with the selection of higher body temperatures, the so-called post-prandial thermophilic response. This study aimed to investigate the excitation–contraction (E–C) coupling in postprandial broad-snouted caimans (Caiman latirostris) in response to acute warming within a preferred body temperature range of crocodiles. Isometric preparations subjected to a temperature transition from 25°C to 30°C were used to investigate myocardial contractility of postprandial caimans, that is, 48 h after the animals ingested a rodent meal corresponding to 15% of body mass. The caiman heart exhibits a negative force–frequency relationship that is independent of the temperature. At 25°C, cardiac muscle was able to maintain a constant force up to 36 bpm, above which it decreased significantly, reaching minimum values at the highest frequency of 84 bpm. Moreover, E–C coupling is predominantly dependent on transsarcolemmal Ca2+ transport denoted by the lack of significant ryanodine effects on force generation. On the contrary, ventricular strips at 30°C were able to sustain the cardiac contractility at higher pacing frequencies (from 12 to 144 bpm) due to an important role of Na+/Ca2+ exchanger in Ca2+ cycling, as indicated by the decay of the post-rest contraction, and a significant contribution of the sarcoplasmic reticulum above 72 bpm. Our results demonstrated that the myocardium of postprandial caimans exhibits a significant degree of thermal plasticity of E–C coupling during acute warming. Therefore, myocardial contractility can be maximized when postprandial broad-snouted caimans select higher body temperatures (preferred temperature zone) following feeding.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Physiological Sciences Federal University of São Carlos-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences Federal University of São Carlos–UFSCar/São Paulo State University UNESP Campus Araraquara-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences Federal University of São Carlos–UFSCar/São Paulo State University UNESP Campus Araraquara-
Formato: dc.format417-425-
Idioma: dc.languageen-
Relação: dc.relationJournal of Experimental Zoology Part A: Ecological and Integrative Physiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectacute warming-
Palavras-chave: dc.subjectcardiac function-
Palavras-chave: dc.subjectexcitation–contraction coupling-
Palavras-chave: dc.subjectfeeding-
Palavras-chave: dc.subjectreptile-
Palavras-chave: dc.subjectspecific dynamic action-
Título: dc.titleEffects of change in temperature on the cardiac contractility of broad-snouted caiman (Caiman latirostris) during digestion-
Tipo de arquivo: dc.typelivro digital-
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