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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Oeste Paulista (UNOESTE) | - |
Autor(es): dc.contributor | Universidade Do Oeste Paulista (UNOESTE) | - |
Autor(es): dc.contributor | Faculty of Medicine of ABC (FMABC) | - |
Autor(es): dc.creator | Veras, Allice Santos Cruz [UNESP] | - |
Autor(es): dc.creator | Gomes, Rayana Loch | - |
Autor(es): dc.creator | Almeida Tavares, Maria Eduarda [UNESP] | - |
Autor(es): dc.creator | Giometti, Inês Cristina | - |
Autor(es): dc.creator | Cardoso, Ana Paula Mattoso Miskulin [UNESP] | - |
Autor(es): dc.creator | da Costa Aguiar Alves, Beatriz | - |
Autor(es): dc.creator | Lenquiste, Sabrina Alves | - |
Autor(es): dc.creator | Vanderlei, Luiz Carlos Marques [UNESP] | - |
Autor(es): dc.creator | Teixeira, Giovana Rampazzo [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:50:20Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:50:20Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1038/s41598-021-85337-9 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207472 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207472 | - |
Descrição: dc.description | The high-fat diet (HFD) stimulates an increase in lipids and can be prejudicial for harmful to prostatic morphogenesis. Polyunsaturated fatty acid (PUFAs) have anti-inflammatory and antioxidant action in some types of cancer. The combination of aerobic physical exercise and PUFA can be more effective and reduce the risk of death. The study evaluates the effects of aerobic physical exercise associated with omega-3 (fish and chia oils), on the ventral prostate of Wistar rats those fed with HFD. Here, we report that HFD modified the final body weight and the weight gain, decreased the expression of the androgen receptor and increased prostatic inflammation via TNF-α produced damage prostatic like intraepithelial neoplasia. The supplementation with fish oil decreases final body weight, reduced BCL-2 and inflammation compared to chia oil; aerobic physical exercise associated with fish oil reduced lipids circulant and prostatic, increased proteins pro-apoptotic expression and reduced IL-6 (p < 0.0001) and TNF-α potentiating the CAT (p = 0.03) and SOD-1 (p = 0.001) expression. Additionally, the chia oil increased the NRF-2 (p < 0.0001) and GSS (p = 0.4) genes. PUFAs reduced the damage caused by excessive high-fat diet in the prostate so that there is greater effectiveness in omega-3 intake, it is necessary to associate with aerobic physical exercise. | - |
Descrição: dc.description | Postgraduate Program in Movement Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | Department of Physical Education School of Technology and Sciences São Paulo State University (UNESP), 19060-900, Street Roberto Simonsen | - |
Descrição: dc.description | Department of Physiotherapy São Paulo State University (UNESP) | - |
Descrição: dc.description | Faculty of Nutrition University of Oeste Paulista (UNOESTE) | - |
Descrição: dc.description | Multicentre Graduate Program in Physiological Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | Faculty of Veterinary Medicine Universidade Do Oeste Paulista (UNOESTE) | - |
Descrição: dc.description | Faculty of Medicine of ABC (FMABC), Santo André | - |
Descrição: dc.description | Experimental Laboratory of Exercise Biology (LEBioEx) São Paulo State University (UNESP) | - |
Descrição: dc.description | Postgraduate Program in Movement Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | Department of Physical Education School of Technology and Sciences São Paulo State University (UNESP), 19060-900, Street Roberto Simonsen | - |
Descrição: dc.description | Department of Physiotherapy São Paulo State University (UNESP) | - |
Descrição: dc.description | Multicentre Graduate Program in Physiological Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | Experimental Laboratory of Exercise Biology (LEBioEx) São Paulo State University (UNESP) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Scientific Reports | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | Supplementation of polyunsaturated fatty acids (PUFAs) and aerobic exercise improve functioning, morphology, and redox balance in prostate obese rats | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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