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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Federal University of São João Del Rei – Midwest Campus Dona Lindu | - |
Autor(es): dc.contributor | Barretos Cancer Hospital | - |
Autor(es): dc.contributor | A.C. Camargo Hospital | - |
Autor(es): dc.creator | Faustino, Simone E. S. | - |
Autor(es): dc.creator | Tjioe, Kellen C. [UNESP] | - |
Autor(es): dc.creator | Assao, Agnes | - |
Autor(es): dc.creator | Pereira, Michele C. | - |
Autor(es): dc.creator | Carvalho, André L. | - |
Autor(es): dc.creator | Kowalski, Luiz P. | - |
Autor(es): dc.creator | Oliveira, Denise T. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:50:16Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:50:16Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1186/s12903-021-01459-6 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/207446 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/207446 | - |
Descrição: dc.description | Background: The aims of this study were to determine intra (ILVD) and peritumoral (PLVD) lymphatic vessel density (LVD), and to investigate the relationship of LVD with occult metastasis and prognosis. Methods: Eighty-seven oral squamous cell carcinomas, in clinical stages I or II, arising in the tongue or floor of the mouth were stained with podoplanin. Lymphatic vessels were quantified in intra and peritumoral areas by sequential analysis and hot spot evaluation. Associations of the ILVD and PLVD with clinicopathologic parameters were determined by Chi-square or Fisher’s exact test. The 5 and 10-year survival rates were calculated by the Kaplan–Meier and compared using the log-rank test. Results: No significant association was observed between ILVD or PLDV and clinicopathologic variables including occult lymph node metastasis, or clinical follow-up. However, ILVD showed a significant association with regional recurrence (p = 0.040). The perineural invasion was associated with PLVD (p = 0.041). Disease-specific (p = 0.044) and disease-free survivals (p = 0.016) had significant association with PLVD. Conclusions: The intra or peritumoral lymphatic vessel density had no predictive value for occult lymph node metastasis in the early stages of oral cancer arising in the tongue or floor of mouth. | - |
Descrição: dc.description | Department of Surgery Stomatology Pathology and Radiology Area of Pathology Bauru School of Dentistry University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75 | - |
Descrição: dc.description | Oral Oncology Center Aracatuba School of Dentistry São Paulo State University (Unesp) | - |
Descrição: dc.description | Federal University of São João Del Rei – Midwest Campus Dona Lindu | - |
Descrição: dc.description | Department of Head and Neck Surgery Barretos Cancer Hospital | - |
Descrição: dc.description | Department of Head and Neck Surgery and Otorhinolaryngology A.C. Camargo Hospital | - |
Descrição: dc.description | Oral Oncology Center Aracatuba School of Dentistry São Paulo State University (Unesp) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | BMC Oral Health | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | D2-40 | - |
Palavras-chave: dc.subject | Lymphatic metastasis | - |
Palavras-chave: dc.subject | Oral squamous cell carcinoma | - |
Palavras-chave: dc.subject | Podoplanin | - |
Palavras-chave: dc.subject | Prognosis | - |
Título: dc.title | Association of lymph vessel density with occult lymph node metastasis and prognosis in oral squamous cell carcinoma | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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