Paracoccidioimycosis and white individuals: Susceptibility and biogeographic aspects in an important endemic area in Brazil

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorZeminian de Oliveira, Luciana Bonome [UNESP]-
Autor(es): dc.creatorDella Coletta, Amanda Manoel [UNESP]-
Autor(es): dc.creatorGardizani, Taiane Priscila [UNESP]-
Autor(es): dc.creatorBarrozo, Ligia Vizeu-
Autor(es): dc.creatorMiot, Hélio Amante [UNESP]-
Autor(es): dc.creatorDe Faveri, Julio [UNESP]-
Autor(es): dc.creatorDias-Melicio, Luciane Alarcão [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:50:11Z-
Data de disponibilização: dc.date.available2022-02-22T00:50:11Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1371/journal.pntd.0009086-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207416-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207416-
Descrição: dc.descriptionParacoccidioidomycosis (PCM) is a neglected mycosis most commonly occurring in Latin America. The etiologic agents are thermo dimorphic fungi of the genus Paracoccidioides, and cause an important granulomatous response in affected tissues. The Botucatu Medical School, from São Paulo State University (UNESP), is a PCM study pole, located in São Paulo State Midwest region, which is classified as a hyperendemic area in the Southeast region in Brazil. This study aimed to perform a retrospective epidemiological, geographical, and clinical analysis by the information available in medical records. It was listed as socio-demographic data along with clinical characteristics from patients diagnosed and treated during a 10-year period in Botucatu, totaling 177 patients with Paracoccidioidomycosis con-firmed by the histopathological test. It was observed that the main clinical presentation was the chronic type (76,3%), most commonly identified in white male individuals over the age of 29 years old, smokers, and alcoholics, providing evidences for the first time that white individuals were more affected by the disease, in comparison to non-white individuals that may be more resistant to infection. This data opens new avenues for study within ancestry, resis-tance and susceptibility in paracoccidioidomycosis.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Laboratory of Immunopathology and Infectious Agents-LIAI UNIPEX-Experimental Research Unity, Sector 5-
Descrição: dc.descriptionUniversity of São Paulo (USP) Department of Geography School of Philosophy Literature and Human Sciences-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Division of Dermatology and Radiotherapy-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Department of Pathology-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Laboratory of Immunopathology and Infectious Agents-LIAI UNIPEX-Experimental Research Unity, Sector 5-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Division of Dermatology and Radiotherapy-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School of Botucatu Department of Pathology-
Descrição: dc.descriptionFAPESP: 2013/24877-9-
Formato: dc.format1-12-
Idioma: dc.languageen-
Relação: dc.relationPLoS Neglected Tropical Diseases-
???dc.source???: dc.sourceScopus-
Título: dc.titleParacoccidioimycosis and white individuals: Susceptibility and biogeographic aspects in an important endemic area in Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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