The baroreflex in aquatic and amphibious teleosts: Does terrestriality represent a significant driving force for the evolution of a more effective baroreflex in vertebrates?

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorAarhus University (AU)-
Autor(es): dc.contributorNational Institute of Science and Technology in Comparative Physiology (INCT – FAPESP/CNPq)-
Autor(es): dc.creatorArmelin, Vinicius Araújo [UNESP]-
Autor(es): dc.creatorBraga, Victor Hugo da Silva [UNESP]-
Autor(es): dc.creatorTeixeira, Mariana Teodoro [UNESP]-
Autor(es): dc.creatorGuagnoni, Igor Noll [UNESP]-
Autor(es): dc.creatorWang, Tobias-
Autor(es): dc.creatorFlorindo, Luiz Henrique [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:49:39Z-
Data de disponibilização: dc.date.available2022-02-22T00:49:39Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.cbpa.2021.110916-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207242-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207242-
Descrição: dc.descriptionAll vertebrates have baroreflexes that provide fast regulation of arterial blood pressure (PA) to maintain adequate tissue perfusion and avoid vascular lesions from excessive pressures. The baroreflex is a negative feedback loop, where altered PA results in reciprocal changes in heart rate (fH) and systemic vascular conductance to restore pressure. In terrestrial environments, gravity usually leads to blood pooling in the lower body reducing venous return, cardiac filling, cardiac output and PA. Conversely, in aquatic environments, the hydrostatic pressure of surrounding water mitigates blood pooling and prevents vascular distensions. In this context, we aimed to test the hypothesis that vertebrate species that were exposed to gravity-induced hemodynamic disturbances throughout their evolutionary histories have a more effective barostatic reflex than those that were not. We examined the cardiac baroreflex of fish that perform (Clarias gariepinus and Hoplerythrinus unitaeniatus) and do not perform (Hoplias malabaricus and Oreochromis niloticus) voluntary terrestrial sojourns, using pharmacological manipulations of PA to characterize reflex changes in fH using a four-variable sigmoidal logistic function (i.e. the “Oxford technique”). Our results revealed that amphibious fish exhibit higher baroreflex gain and responsiveness to hypotension than strictly aquatic fish, suggesting that terrestriality and the gravitational circulatory stresses constitute a relevant driving force for the evolution of a more effective baroreflex in vertebrates. We also demonstrate that strictly aquatic teleosts have considerable baroreflex gain, supporting the view that the baroreflex is an ancient cardiovascular trait that appeared before vertebrates colonized the gravity-dominated realm of land.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Physiology Institute of Biosciences University of São Paulo (USP), Rua do Matão, Travessa 14, 321-
Descrição: dc.descriptionDepartment of Zoology and Botany São Paulo State University (UNESP), Rua Cristóvão Colombo 2265-
Descrição: dc.descriptionSection for Zoophysiology Department of Bioscience Aarhus University (AU), C. F. Møllers Allé 3, Aarhus-
Descrição: dc.descriptionAquaculture Center (CAUNESP) São Paulo State University (UNESP), Rodovia Prof. Paulo Donato Castellane n/n-
Descrição: dc.descriptionNational Institute of Science and Technology in Comparative Physiology (INCT – FAPESP/CNPq)-
Descrição: dc.descriptionDepartment of Zoology and Botany São Paulo State University (UNESP), Rua Cristóvão Colombo 2265-
Descrição: dc.descriptionAquaculture Center (CAUNESP) São Paulo State University (UNESP), Rodovia Prof. Paulo Donato Castellane n/n-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 16/17572-5-
Descrição: dc.descriptionCAPES: 88881.133009/2016-01-
Descrição: dc.descriptionCAPES: 88881.133760/2016-01-
Idioma: dc.languageen-
Relação: dc.relationComparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAutonomic blockade-
Palavras-chave: dc.subjectBaroreceptors-
Palavras-chave: dc.subjectBaroreflex gain-
Palavras-chave: dc.subjectBaroreflex regulatory scope-
Palavras-chave: dc.subjectFish-
Título: dc.titleThe baroreflex in aquatic and amphibious teleosts: Does terrestriality represent a significant driving force for the evolution of a more effective baroreflex in vertebrates?-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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