Synthesis of mussel-inspired polydopamine-gallium nanoparticles for biomedical applications

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Minho-
Autor(es): dc.contributorICVS/3B's-PT Government Associate Laboratory-
Autor(es): dc.creatorTeixeira, Jean Valdir Uchôa [UNESP]-
Autor(es): dc.creatorMaia, Fátima Raquel Azevedo-
Autor(es): dc.creatorCarvalho, Mariana-
Autor(es): dc.creatorReis, Rui-
Autor(es): dc.creatorOliveira, Joaquim Miguel-
Autor(es): dc.creatorLisboa-Filho, Paulo Noronha [UNESP]-
Autor(es): dc.creatorClaro, Ana Paula Rosifni Alves [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:49:22Z-
Data de disponibilização: dc.date.available2022-02-22T00:49:22Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2217/nnm-2020-0312-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207152-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207152-
Descrição: dc.descriptionAim: To established a simple, controlled and reproducible method to synthesize gallium (Ga)-coated polydopamine (PDA) nanoparticles (NPs). Materials & methods: PDA NPs were synthesized in alkali medium with posterior Ga shell formation due to ion chelation on the NP surface. Results: The obtained results with energy-dispersive X-ray spectroscopy confirmed the incorporation of Ga on the PDA NP surface. The cytotoxicity of Ga-coated PDA NPs was evaluated in vitro at different concentrations in contact with human adipose-derived stem cells. Further cell analysis also demonstrated the benefit of Ga-coated PDA NPs, which increased the cell proliferation rate compared with noncoated PDA NPs. Conclusion: This study indicated that Ga could work as an appropriate shell for PDA NPs, inducing cell proliferation at the analyzed concentrations.-
Descrição: dc.descriptionDepartment of Materials and Technology School of Engineering UNESP-São Paulo State University Guaratinguetá Campus-
Descrição: dc.descriptionB'S Research Group I3Bs-Research Institute on Biomaterials Biodegradables and Biomimetics University of Minho-
Descrição: dc.descriptionICVS/3B's-PT Government Associate Laboratory-
Descrição: dc.descriptionSchool of Sciences UNESP-São Paulo State University-
Descrição: dc.descriptionDepartment of Materials and Technology School of Engineering UNESP-São Paulo State University Guaratinguetá Campus-
Descrição: dc.descriptionSchool of Sciences UNESP-São Paulo State University-
Formato: dc.format5-17-
Idioma: dc.languageen-
Relação: dc.relationNanomedicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcore/shell-
Palavras-chave: dc.subjectcytotoxicity-
Palavras-chave: dc.subjectgallium incorporation-
Palavras-chave: dc.subjectnanoparticle synthesis-
Título: dc.titleSynthesis of mussel-inspired polydopamine-gallium nanoparticles for biomedical applications-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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