Structural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorThe University of Melbourne-
Autor(es): dc.contributorUniversity of Groningen-
Autor(es): dc.creatorNogueira, Vinícius Krieger Costa [UNESP]-
Autor(es): dc.creatorMendes Soares, Igor Paulino [UNESP]-
Autor(es): dc.creatorFragelli, Camila Maria Bullio [UNESP]-
Autor(es): dc.creatorBoldieri, Talita [UNESP]-
Autor(es): dc.creatorManton, David John-
Autor(es): dc.creatorBussaneli, Diego Girotto [UNESP]-
Autor(es): dc.creatorCordeiro, Rita de Cássia Loiola [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:49:19Z-
Data de disponibilização: dc.date.available2022-02-22T00:49:19Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2020.103570-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/207137-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/207137-
Descrição: dc.descriptionObjective: To evaluate the influence of fluoride varnish (FV) therapies or resin infiltration (RI) to maintain the structural integrity of Molar Incisor Hypomineralization (MIH) -affected teeth. Methods: Fifty-one children aged 6–12 years with at least one incisor and one first permanent molar with yellow/brown MIH opacities were included. Patients were randomly allocated into three groups: FV – Fluoride Varnish (Duraphat); FV+etch – Fluoride Varnish (Duraphat) after enamel etching with 37% phosphoric acid; or RI – Resin Infiltration system (Icon). Opacities were monitored for 18 months. The primary outcome was the loss of integrity due to post-eruptive enamel breakdown (PEB). Covariables included sex, age, DMFT index, opacity colour, plaque index, number of MIH-affected teeth, and number of MIH-affected surfaces. Fisher's Exact was used to test the association of treatments with PEB, the Kaplan-Meyer method analysed the survival rates and Cox-regression determined which covariables would predict failure (α=0.05). Results: From a total of 235 teeth, the PEB rate for RI (6.1%) was significantly lower (p<0.05) than FV (17.9%; OR 3.0, 95%CI 1.07, 8.48) and FV+etch (17.3%; OR 3.1, 95%CI 1.13, 8.73). DMFT index >3, brown opacities, cusp involvement, and age between 6–8 years predicted PEB (p<0.05). Conclusions: Resin infiltration positively influenced the structural integrity maintenance of MIH-affected teeth by decreasing the risk of enamel breakdown over18 months follow-up. Registry of Clinical Trials (RBR-8wwk3n). Clinical Relevance: Resin infiltration proved to be a more efficacious intervention to maintain the structural integrity of MIH-affected teeth than fluoride varnish therapies.-
Descrição: dc.descriptionDepartment of Morphology and Pediatric Dentistry Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680-
Descrição: dc.descriptionMelbourne Dental School The University of Melbourne-
Descrição: dc.descriptionCariology and Paediatric Dentistry Centrum voor Tandheelkunde en Mondzorgkunde UMCG University of Groningen-
Descrição: dc.descriptionDepartment of Morphology and Pediatric Dentistry Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araraquara School of Dentistry São Paulo State University (UNESP), Rua Humaitá, 1680-
Idioma: dc.languageen-
Relação: dc.relationJournal of Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDental enamel-
Palavras-chave: dc.subjectEnamel defects-
Palavras-chave: dc.subjectFluoride therapy-
Palavras-chave: dc.subjectIcon-
Palavras-chave: dc.subjectMolar incisor hypomineralization-
Palavras-chave: dc.subjectResin infiltration-
Título: dc.titleStructural integrity of MIH-affected teeth after treatment with fluoride varnish or resin infiltration: An 18-Month randomized clinical trial-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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