Evaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol

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Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)-
Autor(es): dc.creatorShiroma, Letícia Sayuri-
Autor(es): dc.creatorSoares, Michelly Pereira [UNESP]-
Autor(es): dc.creatorCardoso, Israel Luz [UNESP]-
Autor(es): dc.creatorIshikawa, Marcia Mayumi-
Autor(es): dc.creatorJonsson, Claudio Martin-
Autor(es): dc.creatorNascimento Queiroz, Sonia Claudia-
Data de aceite: dc.date.accessioned2022-02-22T00:48:52Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:52Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.heliyon.2020.e05716-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206983-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206983-
Descrição: dc.descriptionAntibiotics, Hematological Variables, Oxidative stress, Aquaculture; Agricultural Water Management; Environmental Science; Environmental Risk Assessment; Environmental Toxicology; Toxicology-
Descrição: dc.descriptionIntensive fish cultivation has a high incidence of infection, which is often controlled by administering antibiotics. Florfenicol (FF) is one of the two antimicrobial drugs permitted for aquaculture in Brazil. Due to their intensive use, potentially harmful effects on aquatic organisms are of great concern. In this sense, we investigated whether the presence of FF in cultivation water could change the health parameters of Nile tilapia. For this, we evaluated hemoglobin, hematocrit, mean corpuscular hemoglobin (MCHC) concentration, mean corpuscular volume (MCV), total plasma protein (TPP), number of circulating red blood cells and leukocytes, as lipid peroxidation levels, catalase activity and glutathione S-transferase activity of fish exposed to 11.72 mg L−1 of FF in water for 48 h. The fish were divided into two groups: Nile tilapia in water with FF or without FF (control). Exposure to FF in cultivation water for a short period didn't change the hematological variables analyzed, but caused changes in liver ROS (Reactive oxygen species) markers of the Nile tilapia, which was revealed by lipid peroxidation levels, catalase activity, and glutathione S-transferase. The 48h exposure period was enough to induce oxidative stress in hepatocytes, causing cellular oxidative damage. Therefore, the antibiotic florfenicol may cause toxicity to organisms and aquatic ecosystems, even at a sublethal concentrations near 1/100 LC50-48h for fish species.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionEmpresa Brasileira de Pesquisa Agropecuária-
Descrição: dc.descriptionInstitute of Chemistry University of Campinas, POB 6154-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences Federal University of São Carlos -UFSCar/São Paulo State University UNESP Campus Araraquara-
Descrição: dc.descriptionEmbrapa Environment Brazilian Agricultural Research Corporation (EMBRAPA), Rod. SP 340, Km 127,5, Caixa Postal 69-
Descrição: dc.descriptionJoint Graduate Program in Physiological Sciences Federal University of São Carlos -UFSCar/São Paulo State University UNESP Campus Araraquara-
Descrição: dc.descriptionEmpresa Brasileira de Pesquisa Agropecuária: 0117020010606007-
Idioma: dc.languageen-
Relação: dc.relationHeliyon-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAgricultural water management-
Palavras-chave: dc.subjectAntibiotics-
Palavras-chave: dc.subjectAquaculture-
Palavras-chave: dc.subjectEnvironmental risk assessment-
Palavras-chave: dc.subjectEnvironmental science-
Palavras-chave: dc.subjectEnvironmental toxicology-
Palavras-chave: dc.subjectHematological variables-
Palavras-chave: dc.subjectOxidative stress-
Palavras-chave: dc.subjectToxicology-
Título: dc.titleEvaluation of health and environmental risks for juvenile tilapia (Oreochromis niloticus) exposed to florfenicol-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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