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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Hospital Moinhos de Vento | - |
Autor(es): dc.contributor | Hospital de Clínicas de Passo Fundo | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | University of Amsterdam | - |
Autor(es): dc.creator | Zabot, Gilmara Pandolfo | - |
Autor(es): dc.creator | Cassol, Ornella | - |
Autor(es): dc.creator | Saad-Hossne, Rogerio [UNESP] | - |
Autor(es): dc.creator | Bemelman, Willem | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:48:38Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:48:38Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-11-13 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.3748/wjg.v26.i42.6572 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/206924 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/206924 | - |
Descrição: dc.description | One of the most challenging phenotypes of Crohn's disease is perianal fistulizing disease (PFCD). It occurs in up to 50% of the patients who also have symptoms in other parts of the gastrointestinal tract, and in 5% of the cases it occurs as the first manifestation. It is associated with severe symptoms, such as pain, fecal incontinence, and a significant reduction in quality of life. The presence of perianal disease in conjunction with Crohn's disease portends a significantly worse disease course. These patients require close monitoring to identify those at risk of worsening disease, suboptimal biological drug levels, and signs of developing neoplasm. The last 2 decades have seen significant advancements in the management of PFCD. More recently, newer biologics, cell-based therapies, and novel surgical techniques have been introduced in the hope of improved outcomes. However, in refractory cases, many patients face the decision of having a stoma made and/or a proctectomy performed. In this review, we describe modern surgical management and the most recent advances in the management of complex PFCD, which will likely impact clinical practice. | - |
Descrição: dc.description | Department of Coloproctology Hospital Moinhos de Vento | - |
Descrição: dc.description | Department of Surgery Hospital de Clínicas de Passo Fundo | - |
Descrição: dc.description | Department of Internal Medicine São Paulo State University (Unesp) Medical School | - |
Descrição: dc.description | Department of Surgery Amsterdam University Medical Center University of Amsterdam | - |
Descrição: dc.description | Department of Internal Medicine São Paulo State University (Unesp) Medical School | - |
Formato: dc.format | 6572-6581 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | World Journal of Gastroenterology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Anorectal fistula | - |
Palavras-chave: dc.subject | Crohn's disease | - |
Palavras-chave: dc.subject | Inflammatory bowel disease | - |
Palavras-chave: dc.subject | Perianal fistulas | - |
Palavras-chave: dc.subject | Surgical treatment | - |
Título: dc.title | Modern surgical strategies for perianal Crohn's disease | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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