Modern surgical strategies for perianal Crohn's disease

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorHospital Moinhos de Vento-
Autor(es): dc.contributorHospital de Clínicas de Passo Fundo-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Amsterdam-
Autor(es): dc.creatorZabot, Gilmara Pandolfo-
Autor(es): dc.creatorCassol, Ornella-
Autor(es): dc.creatorSaad-Hossne, Rogerio [UNESP]-
Autor(es): dc.creatorBemelman, Willem-
Data de aceite: dc.date.accessioned2022-02-22T00:48:38Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:38Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-13-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3748/wjg.v26.i42.6572-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206924-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206924-
Descrição: dc.descriptionOne of the most challenging phenotypes of Crohn's disease is perianal fistulizing disease (PFCD). It occurs in up to 50% of the patients who also have symptoms in other parts of the gastrointestinal tract, and in 5% of the cases it occurs as the first manifestation. It is associated with severe symptoms, such as pain, fecal incontinence, and a significant reduction in quality of life. The presence of perianal disease in conjunction with Crohn's disease portends a significantly worse disease course. These patients require close monitoring to identify those at risk of worsening disease, suboptimal biological drug levels, and signs of developing neoplasm. The last 2 decades have seen significant advancements in the management of PFCD. More recently, newer biologics, cell-based therapies, and novel surgical techniques have been introduced in the hope of improved outcomes. However, in refractory cases, many patients face the decision of having a stoma made and/or a proctectomy performed. In this review, we describe modern surgical management and the most recent advances in the management of complex PFCD, which will likely impact clinical practice.-
Descrição: dc.descriptionDepartment of Coloproctology Hospital Moinhos de Vento-
Descrição: dc.descriptionDepartment of Surgery Hospital de Clínicas de Passo Fundo-
Descrição: dc.descriptionDepartment of Internal Medicine São Paulo State University (Unesp) Medical School-
Descrição: dc.descriptionDepartment of Surgery Amsterdam University Medical Center University of Amsterdam-
Descrição: dc.descriptionDepartment of Internal Medicine São Paulo State University (Unesp) Medical School-
Formato: dc.format6572-6581-
Idioma: dc.languageen-
Relação: dc.relationWorld Journal of Gastroenterology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnorectal fistula-
Palavras-chave: dc.subjectCrohn's disease-
Palavras-chave: dc.subjectInflammatory bowel disease-
Palavras-chave: dc.subjectPerianal fistulas-
Palavras-chave: dc.subjectSurgical treatment-
Título: dc.titleModern surgical strategies for perianal Crohn's disease-
Aparece nas coleções:Repositório Institucional - Unesp

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