Non-enzymatic lactose molecularly imprinted sensor based on disposable graphite paper electrode

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.creatorda Silva, José Luiz [UNESP]-
Autor(es): dc.creatorBuffon, Edervaldo [UNESP]-
Autor(es): dc.creatorBeluomini, Maísa Azevedo [UNESP]-
Autor(es): dc.creatorPradela-Filho, Lauro Antonio-
Autor(es): dc.creatorGouveia Araújo, Diele Aparecida-
Autor(es): dc.creatorSantos, André Luiz-
Autor(es): dc.creatorTakeuchi, Regina Massako-
Autor(es): dc.creatorStradiotto, Nelson Ramos [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:48:33Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:33Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-24-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.aca.2020.11.030-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206891-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206891-
Descrição: dc.descriptionLactose (LAC) is a disaccharide - major sugar, present in milk and dairy products. LAC content is an important indicator of milk quality and abnormalities in food industries, as well as in human and animal health. The present study reports the development of an innovative imprinted voltammetric sensor for sensitive detection of LAC. The sensor was constructed using electropolymerized pyrrole (Py) molecularly imprinted polymer (MIP) on graphite paper electrode (PE). The MIP film was constructed through the electrosynthesis of polypyrrole (PPy) in the presence of LAC (template molecule) on PE (PPy/PE). To optimize the detection conditions, several factors affecting the PPy/PE sensor performance were assessed by multivariate methods (Plackett–Burman design and central composite design). Under optimized conditions, the proposed analytical method was applied for LAC detection in whole and LAC-free milks, where it demonstrated high sensitivity and selectivity, with two dynamic linear ranges of concentration (1.0–10 nmol L−1 and 25–125 nmol L−1) and a detection limit of 0.88 nmol L−1. The MIP sensor showed selective molecular recognition for LAC in the presence of structurally related molecules. The proposed PPy/PE sensor exhibited good stability, as well as excellent reproducibility and repeatability. Based on the results obtained, the PPy/PE is found to be highly promising for sensitive detection of LAC.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)-
Descrição: dc.descriptionAnalytical Chemistry Department Institute of Chemistry São Paulo State University (UNESP), 55 Prof. Francisco Degni St., São Paulo State-
Descrição: dc.descriptionInstitute of Exact and Natural Sciences of Pontal Federal University of Uberlandia, 1600 20 St., Ituiutaba, Minas Gerais State-
Descrição: dc.descriptionBioenergy Research Institute (IPBEN) São Paulo State University (UNESP), 55 Prof. Francisco Degni St., São Paulo State-
Descrição: dc.descriptionAnalytical Chemistry Department Institute of Chemistry São Paulo State University (UNESP), 55 Prof. Francisco Degni St., São Paulo State-
Descrição: dc.descriptionBioenergy Research Institute (IPBEN) São Paulo State University (UNESP), 55 Prof. Francisco Degni St., São Paulo State-
Descrição: dc.descriptionFAPESP: 2017/25329–6-
Descrição: dc.descriptionFAPESP: 2018/12131–6-
Descrição: dc.descriptionFAPESP: 2019/13818–8-
Descrição: dc.descriptionCNPq: 408783/2018–4-
Descrição: dc.descriptionCNPq: 443315/2014–0-
Descrição: dc.descriptionCNPq: 447668/2014–5-
Descrição: dc.descriptionCAPES: 88887.368610/2019–00-
Descrição: dc.descriptionFAPEMIG: APQ-02078-15-
Descrição: dc.descriptionFAPEMIG: APQ-02905-15-
Formato: dc.format53-64-
Idioma: dc.languageen-
Relação: dc.relationAnalytica Chimica Acta-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectElectropolymerization-
Palavras-chave: dc.subjectExperimental design-
Palavras-chave: dc.subjectLactose sensing-
Palavras-chave: dc.subjectMolecularly imprinted polymers-
Palavras-chave: dc.subjectNon-enzymatic electroanalysis-
Palavras-chave: dc.subjectPaper-based electrode-
Título: dc.titleNon-enzymatic lactose molecularly imprinted sensor based on disposable graphite paper electrode-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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