Sterilization of scaffolds of calcium phosphates and bacterial cellulose for their use in tissue regeneration

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorCenter of Engineering and Chemical Research-
Autor(es): dc.contributorNational University of Salta-
Autor(es): dc.contributorInnovatec's-Biotechnology Research and Development-
Autor(es): dc.creatorFrancisco, Erick Mark [UNESP]-
Autor(es): dc.creatorZoccolotti, Jacqueline de Oliveira [UNESP]-
Autor(es): dc.creatorTiomnova, Olinka Tiomno-
Autor(es): dc.creatorTolaba, Angel Gustavo-
Autor(es): dc.creatorChanfrau, Jorge Enrique Rodriguez [UNESP]-
Autor(es): dc.creatorJorge, Janaina Habib [UNESP]-
Autor(es): dc.creatorBasmaji, Pierre-
Autor(es): dc.creatorGuastaldi, Antonio Carlos [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:48:25Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:25Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.33263/BRIAC113.1008910098-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206849-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206849-
Descrição: dc.descriptionThe development of biomaterials for the regeneration of tissues is of great importance, and their demand increases every day, due to the increase of the aging population, the expectation, and quality of life, as well as the increase of the accident rates (traffic and violence). Scaffolds are a three-dimensional structure designed to withstand cellular infiltration, growth, and differentiation in order to improve the development and formation of new tissues. Many biomaterials can be used to make these structures, such as bioceramics and biopolymers. However, few studies have been conducted to evaluate its microbiological contamination and the influence of sterilization methods may have on the structure and properties. The objective of this work was to evaluate different sterilization processes and their influence on the physical-chemical properties of Scaffolds made with calcium phosphate and bacterial cellulose. Three sterilization techniques (steam sterilization, ultraviolet radiation sterilization, and microwave sterilization) were evaluated. The results showed that steam sterilization was effective in eliminating microorganisms. Microwave sterilization significantly reduced the amount of CFU / mL, while ultraviolet radiation sterilization did not show efficacy. Changes in the physical-chemical properties of the Scaffolds evaluated after sterilization was not observed, except a slight darkening in the samples treated by steam sterilization or treated by microwave sterilization due to the presence of sodium alginate in the formulation. It was concluded that the steam sterilization process was the most effective.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Physical Chemistry Institute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Dental Materials and Prostheses Araraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionCenter of Engineering and Chemical Research-
Descrição: dc.descriptionMathematics Department Science Faculty National University of Salta-
Descrição: dc.descriptionInnovatec's-Biotechnology Research and Development-
Descrição: dc.descriptionDepartment of Physical Chemistry Institute of Chemistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Dental Materials and Prostheses Araraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2017 / 15487-3-
Formato: dc.format10089-10098-
Idioma: dc.languageen-
Relação: dc.relationBiointerface Research in Applied Chemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBacterial cellulose-
Palavras-chave: dc.subjectCalcium phosphates-
Palavras-chave: dc.subjectScaffolds-
Palavras-chave: dc.subjectStatistical analysis-
Palavras-chave: dc.subjectSterilization process-
Título: dc.titleSterilization of scaffolds of calcium phosphates and bacterial cellulose for their use in tissue regeneration-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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