Prospective application of phthalocyanines in the photodynamic therapy against microorganisms and tumor cells: A mini-review

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorState University of Paraíba-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFacultad de Química-Universidad de la República (UdelaR)-
Autor(es): dc.creatorSantos, Karen Loraine Macena-
Autor(es): dc.creatorBarros, Rafaella Moreno-
Autor(es): dc.creatorda Silva Lima, Diego Paulo-
Autor(es): dc.creatorNunes, Adenia Mirela Alves-
Autor(es): dc.creatorSato, Mariana Rillo [UNESP]-
Autor(es): dc.creatorFaccio, Ricardo-
Autor(es): dc.creatorde Lima Damasceno, Bolívar Ponciano Goulart-
Autor(es): dc.creatorOshiro-Junior, João Augusto-
Data de aceite: dc.date.accessioned2022-02-22T00:48:05Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:05Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.pdpdt.2020.102032-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206773-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206773-
Descrição: dc.descriptionPhthalocyanines are second-generation photosensitizers with photophysical and photochemical properties improved, in comparison to the first-generation. Also, these have shown to be phototoxic against several types of microorganisms and tumor cells. However, challenges such as low solubility in the physiological environment make its single administration unfeasible. Therefore, this review discusses a unique combination of phthalocyanine-loaded in drug delivery carriers for photodynamic therapy in different pathologies' treatment, including nanoemulsion, liposomes, and lipid nanoparticles in an attempt to overcome low solubility drawback. Furthermore, the latest advances to elucidating its mechanisms of action are shown. Subsequently, the manuscript was divided into ten different types of phthalocyanines for medical applications, with a description of their definitions and applications, summarizing the latest preclinical results founded in recent literature.-
Descrição: dc.descriptionGraduation Program in Pharmaceutical Sciences State University of Paraíba-
Descrição: dc.descriptionDepartment of Drugs and Medicines Faculdade de Ciências Farmacêuticas UNESP - Univ. Estadual Paulista, Campus Araraquara-
Descrição: dc.descriptionÁrea Física & Centro NanoMat DETEMA Facultad de Química-Universidad de la República (UdelaR)-
Descrição: dc.descriptionDepartment of Drugs and Medicines Faculdade de Ciências Farmacêuticas UNESP - Univ. Estadual Paulista, Campus Araraquara-
Idioma: dc.languageen-
Relação: dc.relationPhotodiagnosis and Photodynamic Therapy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDrug delivery nanocarriers-
Palavras-chave: dc.subjectNanocarriers-
Palavras-chave: dc.subjectNew therapy-
Palavras-chave: dc.subjectPhotosensitizer-
Palavras-chave: dc.subjectTherapeutic modalities-
Título: dc.titleProspective application of phthalocyanines in the photodynamic therapy against microorganisms and tumor cells: A mini-review-
Aparece nas coleções:Repositório Institucional - Unesp

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