Evaluation of osteoconduction of a synthetic hydroxyapatite/β-tricalcium phosphate block fixed in rabbit mandibles

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorSão Leopoldo Mandic School of Dentistry and Research Center-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Milan-
Autor(es): dc.creatorPires, Luis Carlos de Almeida-
Autor(es): dc.creatorda Silva, Rodrigo Capalbo [UNESP]-
Autor(es): dc.creatorPoli, Pier Paolo-
Autor(es): dc.creatorEsgalha, Fernando Ruas-
Autor(es): dc.creatorHadad, Henrique [UNESP]-
Autor(es): dc.creatorPalin, Letícia Pitol [UNESP]-
Autor(es): dc.creatorSantos, Ana Flávia Piquera [UNESP]-
Autor(es): dc.creatorColombo, Luara Teixiera [UNESP]-
Autor(es): dc.creatorde Jesus, Laís Kawamata [UNESP]-
Autor(es): dc.creatorBassi, Ana Paula Farnezi [UNESP]-
Autor(es): dc.creatorMaiorana, Carlo-
Autor(es): dc.creatorOkamoto, Roberta [UNESP]-
Autor(es): dc.creatorde Carvalho, Paulo Sérgio Perri-
Autor(es): dc.creatorSouza, Francisley Ávila [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:48:05Z-
Data de disponibilização: dc.date.available2022-02-22T00:48:05Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/ma13214902-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206772-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206772-
Descrição: dc.description(1) Background: This study aimed to evaluate the incorporation of hydroxyapatite/β-tricalcium phosphate blocks grafted in rabbit mandibles. (2) Methods: Topographic characterization of biomaterial was performed through scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM-EDX). Ten rabbits randomly received autogenous bone graft harvested from the tibia (Autogenous Group—AG) or synthetic biomaterial manufactured in β-tricalcium phosphate (Biomaterial Group—BG) at their right and left mandibular angles. Euthanasia was performed at 30 and 60 postoperative days; (3) Results: SEM-EDX showed a surface with the formation of crystals clusters. Histological analyses in BG at 30 days showed a slower process of incorporation than AG. At 60 days, BG showed remnants of biomaterial enveloped by bone tissue in the anabolic modeling phase. Histometric analysis showed that mean values of newly formed bone-like tissue in the AG (6.56%/9.70%) were statistically higher compared to BG (3.14%/6.43%) in both periods, respectively. Immunohistochemical analysis demonstrated early bone formation and maturation in the AG with more intense osteopontin and osteocalcin staining. (4) Conclusions: The biomaterial proved to be a possible bone substitute, being incorporated into the receiving bed; however, it showed delayed bone incorporation compared to autogenous bone.-
Descrição: dc.descriptionSão Leopoldo Mandic School of Dentistry and Research Center-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araçatuba Dental School São Paulo State University Júlio de Mesquita Filho—UNESP-
Descrição: dc.descriptionImplant Center for Edentulism and Jawbone Atrophies Maxillofacial Surgery and Odontostomatology Unit Fondazione IRCSS Cà Granda Ospedale Maggiore Policlinico University of Milan-
Descrição: dc.descriptionDepartment of Basic Science Araçatuba Dental School São Paulo State University Júlio de Mesquita Filho—UNESP-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Araçatuba Dental School São Paulo State University Júlio de Mesquita Filho—UNESP-
Descrição: dc.descriptionDepartment of Basic Science Araçatuba Dental School São Paulo State University Júlio de Mesquita Filho—UNESP-
Formato: dc.format1-16-
Idioma: dc.languageen-
Relação: dc.relationMaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiocompatibility-
Palavras-chave: dc.subjectBiomaterials-
Palavras-chave: dc.subjectBone augmentation-
Palavras-chave: dc.subjectBone conduction-
Palavras-chave: dc.subjectBone grafting-
Palavras-chave: dc.subjectCalcium hydroxyapatite-
Palavras-chave: dc.subjectTissue regeneration-
Título: dc.titleEvaluation of osteoconduction of a synthetic hydroxyapatite/β-tricalcium phosphate block fixed in rabbit mandibles-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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