Evaluation of tumescent local anesthesia in cats undergoing unilateral mastectomy

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Federal Rural do Rio de Janeiro-
Autor(es): dc.contributorAutonomous Veterinarian-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorMoreira, Clarissa MR.-
Autor(es): dc.creatorOliveira, Renato LS.-
Autor(es): dc.creatorCosta, Gilberto A.-
Autor(es): dc.creatorCorgozinho, Katia B.-
Autor(es): dc.creatorLuna, Stelio PL. [UNESP]-
Autor(es): dc.creatorSouza, Heloisa JM.-
Data de aceite: dc.date.accessioned2022-02-22T00:47:36Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:36Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.vaa.2020.08.006-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206605-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206605-
Descrição: dc.descriptionObjective: To evaluate the analgesic efficacy and safety of tumescent local anesthesia (TLA) in cats undergoing unilateral mastectomy. Study design: Prospective clinical trial. Animals: A total of 12 ovariohysterectomized female cats. Methods: All animals were premedicated with pethidine (4 mg kg–1) intramuscularly (IM), followed by induction of anesthesia with propofol (5 mg kg–1) intravenously and maintenance with isoflurane in oxygen. A refrigerated TLA solution (15 mL kg–1, 8 °C) was injected using a Klein cannula. The solution was composed of 0.5 mL of epinephrine (1 mg mL–1) and 40 mL of 2% lidocaine added to 210 mL lactated Ringer's solution (final lidocaine concentration 0.32%). Heart and respiratory rates, systolic arterial blood pressure, temperature and oxygen saturation were measured during anesthesia. Blood samples were collected from the jugular vein for measurement of plasma lidocaine concentration using high performance liquid chromatography. Postoperative pain scores were evaluated hourly for 6 hours. Analgesic rescue was performed with tramadol (2 mg kg–1) IM and meloxicam (0.15 mg kg–1) subcutaneously. Results: Plasma lidocaine concentration peaked at 90 minutes after injection of TLA, but no concentration considered toxic for the species was measured. The median postoperative analgesia time was 6 hours after injection of TLA. Conclusions: This study found that TLA prevented sympathetic response to noxious stimuli during anesthesia and provided satisfactory postoperative analgesia in cats submitted to total unilateral mastectomy, with no apparent signs of toxicity. Clinical relevance: TLA can prevent sympathetic stimulation resulting from noxious stimuli during anesthesia, promoting good intraoperative conditions, proving to be a viable addition to analgesia in cats submitted to a total unilateral mastectomy.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionGraduate Program in Veterinary Medicine (Pathology and Clinical Sciences) Universidade Federal Rural do Rio de Janeiro-
Descrição: dc.descriptionAutonomous Veterinarian-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Anaesthesiology Faculty of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Veterinary Medicine and Surgery Universidade Federal Rural do Rio de Janeiro-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Anaesthesiology Faculty of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionCAPES: 88881.188458/2018-01-
Formato: dc.format134-141-
Idioma: dc.languageen-
Relação: dc.relationVeterinary Anaesthesia and Analgesia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectanalgesia-
Palavras-chave: dc.subjectcat-
Palavras-chave: dc.subjectlidocaine-
Palavras-chave: dc.subjectlocal anesthesia-
Palavras-chave: dc.subjectmastectomy-
Palavras-chave: dc.subjecttumescent local anesthesia-
Título: dc.titleEvaluation of tumescent local anesthesia in cats undergoing unilateral mastectomy-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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