Efficacy and Safety of 2 Injection Techniques for Hand Biostimulatory Treatment With Diluted Calcium Hydroxylapatite

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Autor(es): dc.contributorUniversidade Federal de São Paulo (UNIFESP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorFigueredo, Vinícius O-
Autor(es): dc.creatorMiot, Hélio A [UNESP]-
Autor(es): dc.creatorSoares Dias, Juliana-
Autor(es): dc.creatorNunes, Gisele Jacobino de Barros-
Autor(es): dc.creatorBarros de Souza, Marta-
Autor(es): dc.creatorBagatin, Ediléia [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:47:35Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:35Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1097/DSS.0000000000002334-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206595-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206595-
Descrição: dc.descriptionBACKGROUND: Calcium hydroxylapatite (CaHA) is effective for dorsal hand rejuvenation. Higher dilutions are used for biostimulation with fewer side effects. OBJECTIVE: To evaluate the efficacy and safety of 2 techniques of diluted CaHA injection for dorsal hand treatment. METHODS: A prospective, evaluator-blinded study was performed to compare (side-to-side) techniques for treating the dorsum of the hands with diluted CaHA: deep fat lamina or subdermal injection. Fifteen women with aging grades between 1 and 3 on the MHGS (Merz hand grading scale) were enrolled and followed up for 24 weeks. The outcomes were a histological analysis of collagen, skin viscoelasticity, high-frequency ultrasound parameters, MHGS score, and the global aesthetic improvement scale (GAIS) score. RESULTS: Improvement in the MHGS and GAIS scores (p < .01) was observed, with no difference between techniques (p > .05). Skin viscoelasticity measures and ultrasonography for dermal parameters improved for both treatments (p < .01). The mean total collagen density increased from the baseline for both techniques (p < .01). Pain during the procedure as well as adverse effects within the follow-up did not differ between treatments (p > .4). The overall satisfaction was 12% greater for the subdermal technique (p < .05). CONCLUSION: Diluted CaHA improves the skin quality of aging hands with a safe profile, without substantial differences between the techniques.-
Descrição: dc.descriptionCollaborator at Departamento de Dermatologia Escola Paulista de Medicina UNIFESP-
Descrição: dc.descriptionDepartamento de Dermatologia e Radioterapia FMB-Unesp-
Descrição: dc.descriptionDepartamento de Dermatologia e Radioterapia FMB-Unesp-
Formato: dc.formatS54-S61-
Idioma: dc.languageen-
Relação: dc.relationDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]-
???dc.source???: dc.sourceScopus-
Título: dc.titleEfficacy and Safety of 2 Injection Techniques for Hand Biostimulatory Treatment With Diluted Calcium Hydroxylapatite-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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