Breast-milk derived potential probiotics as strategy for the management of childhood obesity

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidad Nacional del Litoral-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorOddi, S.-
Autor(es): dc.creatorHuber, P.-
Autor(es): dc.creatorRocha Faria Duque, A. L. [UNESP]-
Autor(es): dc.creatorVinderola, G.-
Autor(es): dc.creatorSivieri, K. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:47:35Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:35Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.foodres.2020.109673-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206594-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206594-
Descrição: dc.descriptionObesity and overweight, and their concomitant metabolic diseases, emerge as one of the most severe health problems in the world. Prevention and management of obesity are proposed to begin early in childhood, when probiotics may have a role. The Simulator of the Human Intestinal Microbial Ecosystem (SHIME®), in a dynamic validated in vitro system able to simulate the different parts of the gastrointestinal tract, has proven to be useful in analyzing the human intestinal microbial community. L. plantarum 73a and B. animalis subsp. lactis INL1, two strains isolated from breast milk, were assayed in the SHIME® using the fecal microbiota of an obese child. L. plantarum 73a alone or in combination with B. animalis subsp. lactis INL1 demonstrated survival capacity in the SHIME® system. The administration of both strains increased the alpha diversity of the microbiota and reduced the levels of the phylum Proteobacteria. In particular, the genera Escherichia, Shigella, and Clostridium_sensu_stricto_1 were significantly reduced when both strains were administered. The increase of Proteobacteria phylum is generally associated with the microbiota of obese people. Escherichia and Shigella can be involved in inflammation-dependent adiposity and insulin resistance. L. plantarum 73a supplementation reduced ammonia production. L. plantarum 73a alone or in combination with B. animalis subsp. lactis INL1 are potential probiotic candidates for the management of infant obesity.-
Descrição: dc.descriptionAgencia Nacional de Promoción Científica y Tecnológica-
Descrição: dc.descriptionConsejo Nacional de Investigaciones Científicas y Técnicas-
Descrição: dc.descriptionInstituto de Lactología Industrial (INLAIN UNL-CONICET) Facultad de Ingeniería Química Universidad Nacional del Litoral-
Descrição: dc.descriptionLaboratorio de Plancton Instituto Nacional de Limnología (INALI UNL-CONICET) Universidad Nacional del Litoral-
Descrição: dc.descriptionDepartment of Food and Nutrition School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Food and Nutrition School of Pharmaceutical Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionAgencia Nacional de Promoción Científica y Tecnológica: 117/14-
Descrição: dc.descriptionConsejo Nacional de Investigaciones Científicas y Técnicas: PICT-2016-0256-
Idioma: dc.languageen-
Relação: dc.relationFood Research International-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAlpha diversity-
Palavras-chave: dc.subjectBifidobacterium-
Palavras-chave: dc.subjectLactobacillus-
Palavras-chave: dc.subjectMicrobiota-
Palavras-chave: dc.subjectObesity-
Palavras-chave: dc.subjectProbiotic-
Palavras-chave: dc.subjectSHIME®-
Título: dc.titleBreast-milk derived potential probiotics as strategy for the management of childhood obesity-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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