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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | FAMERP | - |
Autor(es): dc.creator | Nogueira, Rodrigo L. | - |
Autor(es): dc.creator | Küpper, Daniel S. | - |
Autor(es): dc.creator | do Bonfim, Caroline M. [UNESP] | - |
Autor(es): dc.creator | Aragon, Davi C. | - |
Autor(es): dc.creator | Damico, Thiago A. | - |
Autor(es): dc.creator | Miura, Carolina S. | - |
Autor(es): dc.creator | Passos, Ivna M. | - |
Autor(es): dc.creator | Nogueira, Maurício L. | - |
Autor(es): dc.creator | Rahal, Paula [UNESP] | - |
Autor(es): dc.creator | Valera, Fabiana C. P. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:47:25Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:47:25Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1111/coa.13640 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/206542 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/206542 | - |
Descrição: dc.description | Objectives: This study aimed to compare the prognosis according to age, genotype or human papillomavirus (HPV) variant in patients with recurrent respiratory papillomatosis (RRP). Design: Non-concurrent cohort. Participants: Forty one patients with RRP. Setting: Tertiary referral hospital. Main Outcome Measures: Disease severity was defined by the number of surgeries performed, and Derkay score at surgeries, obtained from medical records. HPV was detected and genotyped, and HPV-6 variants were also assessed. Results: Fifteen (36.58%) individuals belonged to the juvenile RRP group (JoRRP, less than 18 years), while 26 patients (63.41%) were allocated at the adult group (AoRRP, equal or more than 18 years). JoRRP patients needed, in average, a higher number of surgeries to control the disease than AoRRP patients (mean difference: 3.36). Also, JoRRP patients showed a higher Derkay score at each surgery (mean difference: 3.76). There was no significant difference in the number of surgeries when we compared patients infected with HPV-6 or HPV-11, neither in accordance to HPV-6 variants. Patients with HPV-11 presented a higher mean Derkay score at surgery than those with HPV-6 (mean difference: 4.39); when co-variated by age, we observed that this difference occurred only among JoRRP patients (mean difference: 6.15). Conclusions: Age of onset of RRP has an important impact on number of surgeries to control disease. Patients with JoRRP and HPV-11 tend to present worse Derkay score at each surgery. HPV genotype among adults and HPV-6 variants had no impact on the outcome of the disease. | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Department of Ophthalmology Otorhinolaryngology and Head and Neck Surgery Ribeirão Preto Medical School University of São Paulo (USP) | - |
Descrição: dc.description | Department of Biology IBILCE Institute of Bioscience Language & Literature and Exact Science University of São Paulo State (UNESP) | - |
Descrição: dc.description | Department of Pediatrics Ribeirão Preto Medical School University of São Paulo (USP) | - |
Descrição: dc.description | Laboratory of Research in Virology School of Medicine of São José do Rio Preto FAMERP | - |
Descrição: dc.description | Department of Biology IBILCE Institute of Bioscience Language & Literature and Exact Science University of São Paulo State (UNESP) | - |
Descrição: dc.description | FAPESP: 10/00029-0 | - |
Descrição: dc.description | FAPESP: CNPq | - |
Formato: dc.format | 181-188 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Clinical Otolaryngology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | human papillomavirus | - |
Palavras-chave: dc.subject | outcome | - |
Palavras-chave: dc.subject | recurrent respiratory papillomatosis | - |
Palavras-chave: dc.subject | surgery | - |
Palavras-chave: dc.subject | type | - |
Palavras-chave: dc.subject | variant | - |
Título: dc.title | HPV genotype is a prognosticator for recurrence of respiratory papillomatosis in children | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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