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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Universidade Federal de São Carlos (UFSCar) | - |
Autor(es): dc.creator | Takamiya, Aline Satie [UNESP] | - |
Autor(es): dc.creator | Monteiro, Douglas Roberto [UNESP] | - |
Autor(es): dc.creator | Gorup, Luiz Fernando | - |
Autor(es): dc.creator | Silva, Ebele Adaobi [UNESP] | - |
Autor(es): dc.creator | de Camargo, Emerson Rodriques | - |
Autor(es): dc.creator | Gomes-Filho, João Eduardo [UNESP] | - |
Autor(es): dc.creator | de Oliveira, Sandra Helena Penha [UNESP] | - |
Autor(es): dc.creator | Barbosa, Debora Barros [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:47:19Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:47:19Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.msec.2020.111341 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/206505 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/206505 | - |
Descrição: dc.description | Background: Although silver nanoparticles (SNP) have proven antimicrobial activity against different types of microorganisms, the effect of SNP incorporation into acrylic resin to control Candida albicans biofilm formation aiming at the prevention of Candida-associated denture stomatitis has not yet been fully elucidated. Objectives: This study aimed to evaluate the antimicrobial effect of an acrylic resin containing SNP on C. albicans biofilm growth, the flexural strength of this material and tissue reaction in the subcutaneous connective tissue of rats to SNP. Method: SNP were synthesized through silver nitrate reduction by sodium citrate. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) were used to verify the size and colloidal stability. SNP were added to acrylic resin monomer (Lucitone 550) at 0.05, 0.5 and 5 vol%. The antimicrobial effect against C. albicans (ATCC 10231) was investigated by the enumeration of colony-forming units (CFUs) and SEM. The three-point bending test was performed to analyze the flexural strength. Tissue reaction was evaluated after 7 and 60 days of implantation in the connective tissue of Wistar rats. Results: Spherical particles of 5 and 10 nm were obtained. SNP at 0.05 and 0.5% incorporated into acrylic resin was effective in reducing C. albicans biofilm growth (p < .001). SEM revealed that the material was able to disrupt C. albicans biofilm formation and did not reduce the flexural strength compared to control (p > .05). The inflammatory response observed 60 days after implantation SNP in the subcutaneous tissue was similar to control. Conclusion: It was concluded that SNP addition at 0.05 and 0.5% into acrylic resin exhibited antimicrobial effects against C. albicans biofilm, did not interfere in the flexural strength and may be considered biocompatible. | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | - |
Descrição: dc.description | Department of Diagnosis and Surgery Araçatuba Dental School Univ Estadual Paulista - UNESP | - |
Descrição: dc.description | Department of Pediatric Dentistry and Public Health Dental Araçatuba Dental School Univ Estadual Paulista - UNESP | - |
Descrição: dc.description | LIEC-Department of Chemistry Federal University of São Carlos - UFSCar | - |
Descrição: dc.description | Department of Dental Materials and Prosthodontics Ribeirão Preto Dental School São Paulo State University | - |
Descrição: dc.description | Department of Endodontics Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | Department of Basic Sciences Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | Department of Dental Materials and Prosthodontics Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | Department of Diagnosis and Surgery Araçatuba Dental School Univ Estadual Paulista - UNESP | - |
Descrição: dc.description | Department of Pediatric Dentistry and Public Health Dental Araçatuba Dental School Univ Estadual Paulista - UNESP | - |
Descrição: dc.description | Department of Dental Materials and Prosthodontics Ribeirão Preto Dental School São Paulo State University | - |
Descrição: dc.description | Department of Endodontics Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | Department of Basic Sciences Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | Department of Dental Materials and Prosthodontics Araçatuba Dental School Univ Estadual Paulista – UNESP | - |
Descrição: dc.description | FAPESP: 2010/05788-7 | - |
Descrição: dc.description | CNPq: 577163/2008-6 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Materials Science and Engineering C | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Acrylic resin | - |
Palavras-chave: dc.subject | Antimicrobial | - |
Palavras-chave: dc.subject | Biocompatibility | - |
Palavras-chave: dc.subject | Denture stomatitis | - |
Palavras-chave: dc.subject | Flexural strength | - |
Palavras-chave: dc.subject | Silver nanoparticles | - |
Título: dc.title | Biocompatible silver nanoparticles incorporated in acrylic resin for dental application inhibit Candida albicans biofilm | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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