Fumonisins alter redox balance in Nile tilapia fingerlings

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUNICESUMAR-
Autor(es): dc.contributorUniversity of Georgia-
Autor(es): dc.contributorCollege of Science and Technology from the North of Paraná State-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.creatorLala, Bruno [UNESP]-
Autor(es): dc.creatorSantos, Carolina [UNESP]-
Autor(es): dc.creatorRoldi, Gabriel-
Autor(es): dc.creatorRoça, Roberto [UNESP]-
Autor(es): dc.creatorSampaio, Guilherme [UNESP]-
Autor(es): dc.creatorGarcia, André-
Autor(es): dc.creatorGarrido, Bruno-
Autor(es): dc.creatorRicci, Gleia-
Autor(es): dc.creatorRefundini, Gislaine-
Autor(es): dc.creatorBraccini, Graciela-
Autor(es): dc.creatorPorto, Carla-
Autor(es): dc.creatorGasparino, Eliane-
Autor(es): dc.creatorClaudino-Silva, Stefania Caroline-
Data de aceite: dc.date.accessioned2022-02-22T00:47:18Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:18Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-14-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.aquaculture.2020.735735-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206497-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206497-
Descrição: dc.descriptionFumonisins (FB) are secondary metabolites of Fusarium fungi, and their ingestion are associated with liver disease in different species of animals. This study tests the hypothesis that FB alter redox balance-related gene expression in Nile tilapia fingerlings. A total of 180 fish randomly distributed in four treatments were used: the control treatment (0.0), 20 (FB20), 40 (FB40) and 60 (FB60) mg/kg of FB, to evaluate Glutathione peroxidase (GPX) and heat shock protein (HSP70) mRNA expression in the liver. There was a significant effect of both treatment and exposure period for GPX, evidencing that the response is time-dependent. Similarly, there were exposure time (P <.0001) and diet (P <.0001) effects, as well as their interaction for HSP70 gene expression, but with an increase at 14 days and a reduction at 28 days, showing it to be inversely proportional to GPX. The FB exposure in Nile tilapia fingerlings affects the expression of the genes involved in GPX and HSP70 redox equilibrium, with HSP70 expression initially increased and positive feedback response to GPX, which, in turn, promotes negative feedback response to HSP70 with longer periods of exposure.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Animal Breeding and Nutrition UNESP College of Veterinary Medicine and Animal Sciences São Paulo State University-
Descrição: dc.descriptionSchool of Agriculture UNESP São Paulo State University-
Descrição: dc.descriptionUniversity Center of Maringá UNICESUMAR-
Descrição: dc.descriptionDepartment of Animal and Dairy Sciences UGA University of Georgia-
Descrição: dc.descriptionDepartment of Veterinary Science College of Science and Technology from the North of Paraná State, UniFatecie-
Descrição: dc.descriptionDepartment of Chemistry Labiomass UEM State University of Maringá-
Descrição: dc.descriptionDepartment of Animal Science UEM State University of Maringá-
Descrição: dc.descriptionDepartment of Animal Breeding and Nutrition UNESP College of Veterinary Medicine and Animal Sciences São Paulo State University-
Descrição: dc.descriptionSchool of Agriculture UNESP São Paulo State University-
Descrição: dc.descriptionCNPq: PROC142355/2017-8-
Idioma: dc.languageen-
Relação: dc.relationAquaculture-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectFusarium moniliforme-
Palavras-chave: dc.subjectMycotoxin-
Palavras-chave: dc.subjectOreochromis niloticus-
Palavras-chave: dc.subjectOxidative stress-
Título: dc.titleFumonisins alter redox balance in Nile tilapia fingerlings-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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