Cardioprotection Generated by Aerobic Exercise Training is Not Related to the Proliferation of Cardiomyocytes and Angiotensin-(1-7) Levels in the Hearts of Rats with Supravalvar Aortic Stenosis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorSchool of Physical-
Autor(es): dc.contributorCenter-
Autor(es): dc.contributorFederal University of Paraíba-
Autor(es): dc.contributorDistrict of Rubião Júnior-
Autor(es): dc.creatorAugusto Ferreira Mota, Gustavo [UNESP]-
Autor(es): dc.creatorLuiz Borges de Souza, Sérgio [UNESP]-
Autor(es): dc.creatorLoureiro da Silva, Vitor [UNESP]-
Autor(es): dc.creatorGatto, Mariana [UNESP]-
Autor(es): dc.creatorHenrique Salomé de Campos, Dijon [UNESP]-
Autor(es): dc.creatorGrippa Sant’Ana, Paula [UNESP]-
Autor(es): dc.creatorVileigas, Danielle Fernandes [UNESP]-
Autor(es): dc.creatorPadovani, Carlos Roberto [UNESP]-
Autor(es): dc.creatorCasarini, Dulce Elena-
Autor(es): dc.creatorMenezes de Oliveira, Edilamar-
Autor(es): dc.creatorGarcia Zanati Bazan, Silméia [UNESP]-
Autor(es): dc.creatorFernandes, Tiago-
Autor(es): dc.creatorSugizaki, Mario Mateus [UNESP]-
Autor(es): dc.creatorRicardo de Morais Gomes, Enéas [UNESP]-
Autor(es): dc.creatorCicogna, Antonio Carlos-
Data de aceite: dc.date.accessioned2022-02-22T00:47:17Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:17Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.33594/000000251-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206496-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206496-
Descrição: dc.descriptionBackground/Aims: The beneficial effect of aerobic exercise training (ET) on cardiac remodeling caused by supravalvar aortic stenosis (AS) has been demonstrated in experimental studies; however, the mechanisms responsible for improving cardiac function are not entirely understood. We evaluated whether ET-generated cardioprotection in pressure-overloaded rats is dependent on cardiomyocyte proliferation, increased angiotensin-(1-7) (Ang-1-7) levels, and its receptor in the myocardium. Methods: Eighteen weeks after ascending AS surgery, Wistar rats were randomly assigned to four groups: sedentary control (C-Sed), exercised control (C-Ex), sedentary aortic stenosis (AS-Sed) and exercised aortic stenosis (AS-Ex) groups. The moderate treadmill exercise protocol was performed for ten weeks. The functional capacity was assessed by treadmill exercise testing. Cardiac structure and function were evaluated by echo.-
Descrição: dc.descriptionNorth Carolina Biotechnology Center-
Descrição: dc.descriptionDepartment of Internal Medicine Botucatu Medical School São Paulo State University-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Bioscience São Paulo State University-
Descrição: dc.descriptionDepartment of Medicine Nephrology Division Federal University of São Paulo-
Descrição: dc.descriptionLaboratory of the Biochemistry and Molecular Biology of Exercise School of Physical-
Descrição: dc.descriptionEducation and Sport University of São Paulo-
Descrição: dc.descriptionDepartment of Biotechnology Center-
Descrição: dc.descriptionof Biotechnology Federal University of Paraíba-
Descrição: dc.descriptionDepartment of Internal Medicine São Paulo State University - Unesp-
Descrição: dc.descriptionDistrict of Rubião Júnior, Av. Prof. Mário Rubens Guimarães Montenegro, S/N-
Descrição: dc.descriptionDepartment of Internal Medicine Botucatu Medical School São Paulo State University-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Bioscience São Paulo State University-
Descrição: dc.descriptionDepartment of Internal Medicine São Paulo State University - Unesp-
Formato: dc.format719-735-
Idioma: dc.languageen-
Relação: dc.relationCellular Physiology and Biochemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCardiac dysfunction-
Palavras-chave: dc.subjectCardiac remodeling-
Palavras-chave: dc.subjectCell cycle-
Palavras-chave: dc.subjectPhysical training-
Palavras-chave: dc.subjectRenin-angiotensin system-
Título: dc.titleCardioprotection Generated by Aerobic Exercise Training is Not Related to the Proliferation of Cardiomyocytes and Angiotensin-(1-7) Levels in the Hearts of Rats with Supravalvar Aortic Stenosis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.