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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Netherlands Cancer Institute | - |
Autor(es): dc.contributor | Baylor College of Medicine | - |
Autor(es): dc.contributor | Rice University | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | ShanghaiTech | - |
Autor(es): dc.contributor | Stanford University School of Medicine | - |
Autor(es): dc.contributor | University of Florida | - |
Autor(es): dc.contributor | Cornell University College of Veterinary Medicine | - |
Autor(es): dc.contributor | SeaWorld San Diego | - |
Autor(es): dc.contributor | Moody Gardens | - |
Autor(es): dc.contributor | University of Lausanne | - |
Autor(es): dc.contributor | San Diego | - |
Autor(es): dc.contributor | Leibniz Institute of Plant Genetics and Crop Plant Research (IPK Gatersleben) | - |
Autor(es): dc.contributor | Georg-August-University Göttingen | - |
Autor(es): dc.contributor | University of Western Australia | - |
Autor(es): dc.contributor | National Institutes of Health | - |
Autor(es): dc.contributor | University of Melbourne | - |
Autor(es): dc.contributor | Agricultural Research Service | - |
Autor(es): dc.contributor | Stanford University | - |
Autor(es): dc.contributor | Davis | - |
Autor(es): dc.contributor | San Diego State University | - |
Autor(es): dc.contributor | University of Missouri | - |
Autor(es): dc.contributor | Jackson Laboratory | - |
Autor(es): dc.contributor | Universidad Pablo de Olavide | - |
Autor(es): dc.contributor | Carnegie Mellon University | - |
Autor(es): dc.contributor | Broad Institute of MIT and Harvard | - |
Autor(es): dc.contributor | Uppsala University | - |
Autor(es): dc.contributor | University of East Anglia | - |
Autor(es): dc.contributor | National Institute of Genetics | - |
Autor(es): dc.contributor | Sokendai (Graduate University for Advanced Studies) | - |
Autor(es): dc.contributor | University of Texas MD Anderson Cancer Center | - |
Autor(es): dc.contributor | Northeastern University | - |
Autor(es): dc.contributor | Novartis Institutes for Biomedical Research | - |
Autor(es): dc.contributor | Janssen Vaccines and Prevention BV | - |
Autor(es): dc.contributor | University Medical Centre Rotterdam | - |
Autor(es): dc.contributor | Zoetis (VMRD Global Biologics Research) | - |
Autor(es): dc.contributor | University of Colorado Advanced Reproductive Medicine | - |
Autor(es): dc.creator | Hoencamp, Claire | - |
Autor(es): dc.creator | Dudchenko, Olga | - |
Autor(es): dc.creator | Elbatsh, Ahmed M.O. | - |
Autor(es): dc.creator | Brahmachari, Sumitabha | - |
Autor(es): dc.creator | Raaijmakers, Jonne A. | - |
Autor(es): dc.creator | van Schaik, Tom | - |
Autor(es): dc.creator | Cacciatore, Ángela Sedeño | - |
Autor(es): dc.creator | Contessoto, Vinícius G. [UNESP] | - |
Autor(es): dc.creator | van Heesbeen, Roy G.H.P. | - |
Autor(es): dc.creator | van den Broek, Bram | - |
Autor(es): dc.creator | Mhaskar, Aditya N. | - |
Autor(es): dc.creator | Teunissen, Hans | - |
Autor(es): dc.creator | St Hilaire, Brian Glenn | - |
Autor(es): dc.creator | Weisz, David | - |
Autor(es): dc.creator | Omer, Arina D. | - |
Autor(es): dc.creator | Pham, Melanie | - |
Autor(es): dc.creator | Colaric, Zane | - |
Autor(es): dc.creator | Yang, Zhenzhen | - |
Autor(es): dc.creator | Rao, Suhas S.P. | - |
Autor(es): dc.creator | Mitra, Namita | - |
Autor(es): dc.creator | Lui, Christopher | - |
Autor(es): dc.creator | Yao, Weijie | - |
Autor(es): dc.creator | Khan, Ruqayya | - |
Autor(es): dc.creator | Moroz, Leonid L. | - |
Autor(es): dc.creator | Kohn, Andrea | - |
Autor(es): dc.creator | St. Leger, Judy | - |
Autor(es): dc.creator | Mena, Alexandria | - |
Autor(es): dc.creator | Holcroft, Karen | - |
Autor(es): dc.creator | Gambetta, Maria Cristina | - |
Autor(es): dc.creator | Lim, Fabian | - |
Autor(es): dc.creator | Farley, Emma | - |
Autor(es): dc.creator | Stein, Nils | - |
Autor(es): dc.creator | Haddad, Alexander | - |
Autor(es): dc.creator | Chauss, Daniel | - |
Autor(es): dc.creator | Mutlu, Ayse Sena | - |
Autor(es): dc.creator | Wang, Meng C. | - |
Autor(es): dc.creator | Young, Neil D. | - |
Autor(es): dc.creator | Hildebrandt, Evin | - |
Autor(es): dc.creator | Cheng, Hans H. | - |
Autor(es): dc.creator | Knight, Christopher J. | - |
Autor(es): dc.creator | Burnham, Theresa L.U. | - |
Autor(es): dc.creator | Hovel, Kevin A. | - |
Autor(es): dc.creator | Beel, Andrew J. | - |
Autor(es): dc.creator | Mattei, Pierre-Jean | - |
Autor(es): dc.creator | Kornberg, Roger D. | - |
Autor(es): dc.creator | Warren, Wesley C. | - |
Autor(es): dc.creator | Cary, Gregory | - |
Autor(es): dc.creator | Gómez-Skarmeta, José Luis | - |
Autor(es): dc.creator | Hinman, Veronica | - |
Autor(es): dc.creator | Lindblad-Toh, Kerstin | - |
Autor(es): dc.creator | Palma, Federica Di | - |
Autor(es): dc.creator | Maeshima, Kazuhiro | - |
Autor(es): dc.creator | Multani, Asha S. | - |
Autor(es): dc.creator | Pathak, Sen | - |
Autor(es): dc.creator | Nel-Themaat, Liesl | - |
Autor(es): dc.creator | Behringer, Richard R. | - |
Autor(es): dc.creator | Kaur, Parwinder | - |
Autor(es): dc.creator | Medema, René H. | - |
Autor(es): dc.creator | van Steensel, Bas | - |
Autor(es): dc.creator | de Wit, Elzo | - |
Autor(es): dc.creator | Onuchic, José N. | - |
Autor(es): dc.creator | Di Pierro, Michele | - |
Autor(es): dc.creator | Aiden, Erez Lieberman | - |
Autor(es): dc.creator | Rowland, Benjamin D. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:47:00Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:47:00Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-05-28 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1126/science.abe2218 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/206403 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/206403 | - |
Descrição: dc.description | We investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional (3D) genome architectures at the chromosome scale. Each type appears and disappears repeatedly during eukaryotic evolution. The type of genome architecture that an organism exhibits correlates with the absence of condensin II subunits. Moreover, condensin II depletion converts the architecture of the human genome to a state resembling that seen in organisms such as fungi or mosquitoes. In this state, centromeres cluster together at nucleoli, and heterochromatin domains merge. We propose a physical model in which lengthwise compaction of chromosomes by condensin II during mitosis determines chromosome-scale genome architecture, with effects that are retained during the subsequent interphase. This mechanism likely has been conserved since the last common ancestor of all eukaryotes. | - |
Descrição: dc.description | National Science Foundation | - |
Descrição: dc.description | National Institutes of Health | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | U.S. Department of Agriculture | - |
Descrição: dc.description | Ministry of Education, Culture, Sports, Science and Technology | - |
Descrição: dc.description | European Research Council | - |
Descrição: dc.description | Ministerio de Economía y Competitividad | - |
Descrição: dc.description | Welch Foundation | - |
Descrição: dc.description | National Human Genome Research Institute | - |
Descrição: dc.description | Division of Gene Regulation Netherlands Cancer Institute | - |
Descrição: dc.description | Center for Genome Architecture Baylor College of Medicine | - |
Descrição: dc.description | Department of Molecular and Human Genetics Baylor College of Medicine | - |
Descrição: dc.description | Center for Theoretical Biological Physics Rice University | - |
Descrição: dc.description | Division of Cell Biology Oncode Institute Netherlands Cancer Institute | - |
Descrição: dc.description | Division of Gene Regulation Oncode Institute Netherlands Cancer Institute | - |
Descrição: dc.description | Department of Physics Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | BioImaging Facility Netherlands Cancer Institute | - |
Descrição: dc.description | Shanghai Institute for Advanced Immunochemical Studies ShanghaiTech | - |
Descrição: dc.description | Department of Structural Biology Stanford University School of Medicine | - |
Descrição: dc.description | Whitney Laboratory and Department of Neuroscience University of Florida | - |
Descrição: dc.description | Department of Biosciences Cornell University College of Veterinary Medicine | - |
Descrição: dc.description | SeaWorld San Diego | - |
Descrição: dc.description | Moody Gardens | - |
Descrição: dc.description | Center for Integrative Genomics University of Lausanne | - |
Descrição: dc.description | Department of Medicine and Molecular Biology University of California San Diego | - |
Descrição: dc.description | Leibniz Institute of Plant Genetics and Crop Plant Research (IPK Gatersleben) | - |
Descrição: dc.description | Center of Integrated Breeding Research (CiBreed) Department of Crop Sciences Georg-August-University Göttingen | - |
Descrição: dc.description | UWA School of Agriculture and Environment University of Western Australia | - |
Descrição: dc.description | National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health | - |
Descrição: dc.description | Huffington Center on Aging Baylor College of Medicine | - |
Descrição: dc.description | Howard Hughes Medical Institute Baylor College of Medicine | - |
Descrição: dc.description | Faculty of Veterinary and Agricultural Sciences University of Melbourne | - |
Descrição: dc.description | Avian Diseases and Oncology Laboratory US Department of Agriculture Agricultural Research Service | - |
Descrição: dc.description | Hopkins Marine Station Stanford University | - |
Descrição: dc.description | Department of Wildlife Fish and Conservation Biology University of California Davis | - |
Descrição: dc.description | Coastal and Marine Institute Department of Biology San Diego State University | - |
Descrição: dc.description | Department of Animal Sciences University of Missouri | - |
Descrição: dc.description | Jackson Laboratory | - |
Descrição: dc.description | Centro Andaluz de Biología del Desarrollo CSIC Universidad Pablo de Olavide | - |
Descrição: dc.description | Department of Biological Sciences Carnegie Mellon University | - |
Descrição: dc.description | Broad Institute of MIT and Harvard | - |
Descrição: dc.description | Science for Life Laboratory Department of Medical Biochemistry and Microbiology Uppsala University | - |
Descrição: dc.description | Department of Biological Sciences University of East Anglia | - |
Descrição: dc.description | Genome Dynamics Laboratory National Institute of Genetics | - |
Descrição: dc.description | Department of Genetics Sokendai (Graduate University for Advanced Studies) | - |
Descrição: dc.description | Department of Genetics University of Texas MD Anderson Cancer Center | - |
Descrição: dc.description | Departments of Physics and Astronomy Chemistry and Biosciences Rice University | - |
Descrição: dc.description | Department of Physics Northeastern University | - |
Descrição: dc.description | Novartis Institutes for Biomedical Research | - |
Descrição: dc.description | Janssen Vaccines and Prevention BV | - |
Descrição: dc.description | Department of Developmental Biology Erasmus MC University Medical Centre Rotterdam | - |
Descrição: dc.description | Zoetis (VMRD Global Biologics Research) | - |
Descrição: dc.description | University of Colorado Advanced Reproductive Medicine | - |
Descrição: dc.description | Department of Physics Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP) | - |
Descrição: dc.description | National Science Foundation: 1548121 | - |
Descrição: dc.description | National Science Foundation: 1557923 | - |
Descrição: dc.description | National Science Foundation: 1645219 | - |
Descrição: dc.description | National Institutes of Health: 1R01NS114491 | - |
Descrição: dc.description | FAPESP: 2016/13998-8 | - |
Descrição: dc.description | U.S. Department of Agriculture: 2017-05741 | - |
Descrição: dc.description | FAPESP: 2017/09662-7 | - |
Descrição: dc.description | Ministry of Education, Culture, Sports, Science and Technology: 20H05936 | - |
Descrição: dc.description | European Research Council: 637597 | - |
Descrição: dc.description | European Research Council: 740041 | - |
Descrição: dc.description | European Research Council: 772471 | - |
Descrição: dc.description | Ministerio de Economía y Competitividad: BFU2016-74961-P | - |
Descrição: dc.description | Welch Foundation: C-1792 | - |
Descrição: dc.description | National Science Foundation: CHE-1614101 | - |
Descrição: dc.description | National Science Foundation: DBI-2021795 | - |
Descrição: dc.description | National Institutes of Health: DP1DK113644 | - |
Descrição: dc.description | National Human Genome Research Institute: DP2HG010013 | - |
Descrição: dc.description | National Institutes of Health: NIH1P41HD071837 | - |
Descrição: dc.description | National Science Foundation: PHY-2019745 | - |
Descrição: dc.description | Welch Foundation: Q-1866 | - |
Descrição: dc.description | National Institutes of Health: R01AG045183 | - |
Descrição: dc.description | National Institutes of Health: R01AG062257 | - |
Descrição: dc.description | National Institutes of Health: R01AT009050 | - |
Descrição: dc.description | National Institutes of Health: RO1DK121366 | - |
Descrição: dc.description | National Institutes of Health: U54DK107965 | - |
Descrição: dc.description | National Institutes of Health: UM1HG009375 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Science | - |
???dc.source???: dc.source | Scopus | - |
Título: dc.title | 3D genomics across the tree of life reveals condensin II as a determinant of architecture type | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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