3D genomics across the tree of life reveals condensin II as a determinant of architecture type

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Autor(es): dc.contributorNetherlands Cancer Institute-
Autor(es): dc.contributorBaylor College of Medicine-
Autor(es): dc.contributorRice University-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorShanghaiTech-
Autor(es): dc.contributorStanford University School of Medicine-
Autor(es): dc.contributorUniversity of Florida-
Autor(es): dc.contributorCornell University College of Veterinary Medicine-
Autor(es): dc.contributorSeaWorld San Diego-
Autor(es): dc.contributorMoody Gardens-
Autor(es): dc.contributorUniversity of Lausanne-
Autor(es): dc.contributorSan Diego-
Autor(es): dc.contributorLeibniz Institute of Plant Genetics and Crop Plant Research (IPK Gatersleben)-
Autor(es): dc.contributorGeorg-August-University Göttingen-
Autor(es): dc.contributorUniversity of Western Australia-
Autor(es): dc.contributorNational Institutes of Health-
Autor(es): dc.contributorUniversity of Melbourne-
Autor(es): dc.contributorAgricultural Research Service-
Autor(es): dc.contributorStanford University-
Autor(es): dc.contributorDavis-
Autor(es): dc.contributorSan Diego State University-
Autor(es): dc.contributorUniversity of Missouri-
Autor(es): dc.contributorJackson Laboratory-
Autor(es): dc.contributorUniversidad Pablo de Olavide-
Autor(es): dc.contributorCarnegie Mellon University-
Autor(es): dc.contributorBroad Institute of MIT and Harvard-
Autor(es): dc.contributorUppsala University-
Autor(es): dc.contributorUniversity of East Anglia-
Autor(es): dc.contributorNational Institute of Genetics-
Autor(es): dc.contributorSokendai (Graduate University for Advanced Studies)-
Autor(es): dc.contributorUniversity of Texas MD Anderson Cancer Center-
Autor(es): dc.contributorNortheastern University-
Autor(es): dc.contributorNovartis Institutes for Biomedical Research-
Autor(es): dc.contributorJanssen Vaccines and Prevention BV-
Autor(es): dc.contributorUniversity Medical Centre Rotterdam-
Autor(es): dc.contributorZoetis (VMRD Global Biologics Research)-
Autor(es): dc.contributorUniversity of Colorado Advanced Reproductive Medicine-
Autor(es): dc.creatorHoencamp, Claire-
Autor(es): dc.creatorDudchenko, Olga-
Autor(es): dc.creatorElbatsh, Ahmed M.O.-
Autor(es): dc.creatorBrahmachari, Sumitabha-
Autor(es): dc.creatorRaaijmakers, Jonne A.-
Autor(es): dc.creatorvan Schaik, Tom-
Autor(es): dc.creatorCacciatore, Ángela Sedeño-
Autor(es): dc.creatorContessoto, Vinícius G. [UNESP]-
Autor(es): dc.creatorvan Heesbeen, Roy G.H.P.-
Autor(es): dc.creatorvan den Broek, Bram-
Autor(es): dc.creatorMhaskar, Aditya N.-
Autor(es): dc.creatorTeunissen, Hans-
Autor(es): dc.creatorSt Hilaire, Brian Glenn-
Autor(es): dc.creatorWeisz, David-
Autor(es): dc.creatorOmer, Arina D.-
Autor(es): dc.creatorPham, Melanie-
Autor(es): dc.creatorColaric, Zane-
Autor(es): dc.creatorYang, Zhenzhen-
Autor(es): dc.creatorRao, Suhas S.P.-
Autor(es): dc.creatorMitra, Namita-
Autor(es): dc.creatorLui, Christopher-
Autor(es): dc.creatorYao, Weijie-
Autor(es): dc.creatorKhan, Ruqayya-
Autor(es): dc.creatorMoroz, Leonid L.-
Autor(es): dc.creatorKohn, Andrea-
Autor(es): dc.creatorSt. Leger, Judy-
Autor(es): dc.creatorMena, Alexandria-
Autor(es): dc.creatorHolcroft, Karen-
Autor(es): dc.creatorGambetta, Maria Cristina-
Autor(es): dc.creatorLim, Fabian-
Autor(es): dc.creatorFarley, Emma-
Autor(es): dc.creatorStein, Nils-
Autor(es): dc.creatorHaddad, Alexander-
Autor(es): dc.creatorChauss, Daniel-
Autor(es): dc.creatorMutlu, Ayse Sena-
Autor(es): dc.creatorWang, Meng C.-
Autor(es): dc.creatorYoung, Neil D.-
Autor(es): dc.creatorHildebrandt, Evin-
Autor(es): dc.creatorCheng, Hans H.-
Autor(es): dc.creatorKnight, Christopher J.-
Autor(es): dc.creatorBurnham, Theresa L.U.-
Autor(es): dc.creatorHovel, Kevin A.-
Autor(es): dc.creatorBeel, Andrew J.-
Autor(es): dc.creatorMattei, Pierre-Jean-
Autor(es): dc.creatorKornberg, Roger D.-
Autor(es): dc.creatorWarren, Wesley C.-
Autor(es): dc.creatorCary, Gregory-
Autor(es): dc.creatorGómez-Skarmeta, José Luis-
Autor(es): dc.creatorHinman, Veronica-
Autor(es): dc.creatorLindblad-Toh, Kerstin-
Autor(es): dc.creatorPalma, Federica Di-
Autor(es): dc.creatorMaeshima, Kazuhiro-
Autor(es): dc.creatorMultani, Asha S.-
Autor(es): dc.creatorPathak, Sen-
Autor(es): dc.creatorNel-Themaat, Liesl-
Autor(es): dc.creatorBehringer, Richard R.-
Autor(es): dc.creatorKaur, Parwinder-
Autor(es): dc.creatorMedema, René H.-
Autor(es): dc.creatorvan Steensel, Bas-
Autor(es): dc.creatorde Wit, Elzo-
Autor(es): dc.creatorOnuchic, José N.-
Autor(es): dc.creatorDi Pierro, Michele-
Autor(es): dc.creatorAiden, Erez Lieberman-
Autor(es): dc.creatorRowland, Benjamin D.-
Data de aceite: dc.date.accessioned2022-02-22T00:47:00Z-
Data de disponibilização: dc.date.available2022-02-22T00:47:00Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-05-28-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1126/science.abe2218-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/206403-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/206403-
Descrição: dc.descriptionWe investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional (3D) genome architectures at the chromosome scale. Each type appears and disappears repeatedly during eukaryotic evolution. The type of genome architecture that an organism exhibits correlates with the absence of condensin II subunits. Moreover, condensin II depletion converts the architecture of the human genome to a state resembling that seen in organisms such as fungi or mosquitoes. In this state, centromeres cluster together at nucleoli, and heterochromatin domains merge. We propose a physical model in which lengthwise compaction of chromosomes by condensin II during mitosis determines chromosome-scale genome architecture, with effects that are retained during the subsequent interphase. This mechanism likely has been conserved since the last common ancestor of all eukaryotes.-
Descrição: dc.descriptionNational Science Foundation-
Descrição: dc.descriptionNational Institutes of Health-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionU.S. Department of Agriculture-
Descrição: dc.descriptionMinistry of Education, Culture, Sports, Science and Technology-
Descrição: dc.descriptionEuropean Research Council-
Descrição: dc.descriptionMinisterio de Economía y Competitividad-
Descrição: dc.descriptionWelch Foundation-
Descrição: dc.descriptionNational Human Genome Research Institute-
Descrição: dc.descriptionDivision of Gene Regulation Netherlands Cancer Institute-
Descrição: dc.descriptionCenter for Genome Architecture Baylor College of Medicine-
Descrição: dc.descriptionDepartment of Molecular and Human Genetics Baylor College of Medicine-
Descrição: dc.descriptionCenter for Theoretical Biological Physics Rice University-
Descrição: dc.descriptionDivision of Cell Biology Oncode Institute Netherlands Cancer Institute-
Descrição: dc.descriptionDivision of Gene Regulation Oncode Institute Netherlands Cancer Institute-
Descrição: dc.descriptionDepartment of Physics Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionBioImaging Facility Netherlands Cancer Institute-
Descrição: dc.descriptionShanghai Institute for Advanced Immunochemical Studies ShanghaiTech-
Descrição: dc.descriptionDepartment of Structural Biology Stanford University School of Medicine-
Descrição: dc.descriptionWhitney Laboratory and Department of Neuroscience University of Florida-
Descrição: dc.descriptionDepartment of Biosciences Cornell University College of Veterinary Medicine-
Descrição: dc.descriptionSeaWorld San Diego-
Descrição: dc.descriptionMoody Gardens-
Descrição: dc.descriptionCenter for Integrative Genomics University of Lausanne-
Descrição: dc.descriptionDepartment of Medicine and Molecular Biology University of California San Diego-
Descrição: dc.descriptionLeibniz Institute of Plant Genetics and Crop Plant Research (IPK Gatersleben)-
Descrição: dc.descriptionCenter of Integrated Breeding Research (CiBreed) Department of Crop Sciences Georg-August-University Göttingen-
Descrição: dc.descriptionUWA School of Agriculture and Environment University of Western Australia-
Descrição: dc.descriptionNational Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health-
Descrição: dc.descriptionHuffington Center on Aging Baylor College of Medicine-
Descrição: dc.descriptionHoward Hughes Medical Institute Baylor College of Medicine-
Descrição: dc.descriptionFaculty of Veterinary and Agricultural Sciences University of Melbourne-
Descrição: dc.descriptionAvian Diseases and Oncology Laboratory US Department of Agriculture Agricultural Research Service-
Descrição: dc.descriptionHopkins Marine Station Stanford University-
Descrição: dc.descriptionDepartment of Wildlife Fish and Conservation Biology University of California Davis-
Descrição: dc.descriptionCoastal and Marine Institute Department of Biology San Diego State University-
Descrição: dc.descriptionDepartment of Animal Sciences University of Missouri-
Descrição: dc.descriptionJackson Laboratory-
Descrição: dc.descriptionCentro Andaluz de Biología del Desarrollo CSIC Universidad Pablo de Olavide-
Descrição: dc.descriptionDepartment of Biological Sciences Carnegie Mellon University-
Descrição: dc.descriptionBroad Institute of MIT and Harvard-
Descrição: dc.descriptionScience for Life Laboratory Department of Medical Biochemistry and Microbiology Uppsala University-
Descrição: dc.descriptionDepartment of Biological Sciences University of East Anglia-
Descrição: dc.descriptionGenome Dynamics Laboratory National Institute of Genetics-
Descrição: dc.descriptionDepartment of Genetics Sokendai (Graduate University for Advanced Studies)-
Descrição: dc.descriptionDepartment of Genetics University of Texas MD Anderson Cancer Center-
Descrição: dc.descriptionDepartments of Physics and Astronomy Chemistry and Biosciences Rice University-
Descrição: dc.descriptionDepartment of Physics Northeastern University-
Descrição: dc.descriptionNovartis Institutes for Biomedical Research-
Descrição: dc.descriptionJanssen Vaccines and Prevention BV-
Descrição: dc.descriptionDepartment of Developmental Biology Erasmus MC University Medical Centre Rotterdam-
Descrição: dc.descriptionZoetis (VMRD Global Biologics Research)-
Descrição: dc.descriptionUniversity of Colorado Advanced Reproductive Medicine-
Descrição: dc.descriptionDepartment of Physics Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionNational Science Foundation: 1548121-
Descrição: dc.descriptionNational Science Foundation: 1557923-
Descrição: dc.descriptionNational Science Foundation: 1645219-
Descrição: dc.descriptionNational Institutes of Health: 1R01NS114491-
Descrição: dc.descriptionFAPESP: 2016/13998-8-
Descrição: dc.descriptionU.S. Department of Agriculture: 2017-05741-
Descrição: dc.descriptionFAPESP: 2017/09662-7-
Descrição: dc.descriptionMinistry of Education, Culture, Sports, Science and Technology: 20H05936-
Descrição: dc.descriptionEuropean Research Council: 637597-
Descrição: dc.descriptionEuropean Research Council: 740041-
Descrição: dc.descriptionEuropean Research Council: 772471-
Descrição: dc.descriptionMinisterio de Economía y Competitividad: BFU2016-74961-P-
Descrição: dc.descriptionWelch Foundation: C-1792-
Descrição: dc.descriptionNational Science Foundation: CHE-1614101-
Descrição: dc.descriptionNational Science Foundation: DBI-2021795-
Descrição: dc.descriptionNational Institutes of Health: DP1DK113644-
Descrição: dc.descriptionNational Human Genome Research Institute: DP2HG010013-
Descrição: dc.descriptionNational Institutes of Health: NIH1P41HD071837-
Descrição: dc.descriptionNational Science Foundation: PHY-2019745-
Descrição: dc.descriptionWelch Foundation: Q-1866-
Descrição: dc.descriptionNational Institutes of Health: R01AG045183-
Descrição: dc.descriptionNational Institutes of Health: R01AG062257-
Descrição: dc.descriptionNational Institutes of Health: R01AT009050-
Descrição: dc.descriptionNational Institutes of Health: RO1DK121366-
Descrição: dc.descriptionNational Institutes of Health: U54DK107965-
Descrição: dc.descriptionNational Institutes of Health: UM1HG009375-
Idioma: dc.languageen-
Relação: dc.relationScience-
???dc.source???: dc.sourceScopus-
Título: dc.title3D genomics across the tree of life reveals condensin II as a determinant of architecture type-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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