Atenção: Todas as denúncias são sigilosas e sua identidade será preservada.
Os campos nome e e-mail são de preenchimento opcional
Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Gabbai-Armelin, Paulo Roberto [UNESP] | - |
Autor(es): dc.creator | de Oliveira, Analú Barros [UNESP] | - |
Autor(es): dc.creator | Ferrisse, Túlio Morandin [UNESP] | - |
Autor(es): dc.creator | Sales, Luciana Solera [UNESP] | - |
Autor(es): dc.creator | Barbosa, Elis Rodrigues Oliveira [UNESP] | - |
Autor(es): dc.creator | Miranda, Marina Lins [UNESP] | - |
Autor(es): dc.creator | Salomão, Karina Borges [UNESP] | - |
Autor(es): dc.creator | Brighenti, Fernanda Lourenção [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:46:28Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:46:28Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1111/eci.13559 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/206207 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/206207 | - |
Descrição: dc.description | Background: COVID-19 is an infectious disease caused by SARS-CoV-2 associated with haematological manifestations (thrombolytic events). Aims: Considering the high prevalence of the thrombotic scenarios associated with COVID-19, the aim of this study was to perform a systematic review of the available literature, concerning the relation of COVID-19 and the thrombotic events, and identify prognostic factors for these events. Materials & Methods: PubMed, Web of Science and Scopus databases were searched. Independent reviewers conducted all flow diagram steps. For qualitative analysis, Oxford level of evidence and Newcastle-Ottawa scale were used in the eligible articles. For the prognostic factors, a meta-analysis was conducted to age, number of neutrophils and platelets, and levels of ferritin, C-reactive protein, lactate dehydrogenase and D-dimer. Publication bias was accessed by funnel plot and by trim-and-fill test. Trim-and-fill test was also applied to evaluate meta-analysis bias. Results: Twenty articles were included in the qualitative analysis, and 6 articles were included in the meta-analysis. Case-control studies showed bias related to exposure, and the main bias in cohort studies were related to selection and outcome. All articles received score 4 for the level of evidence. Hypertension and diabetes were the comorbidities more frequently associated with thrombolytic events. Significant results were found regarding D-dimer (P <.0001) and age (P =.0202) for thrombotic events in patients diagnosed with COVID-19. Conclusion: Patients older than 60 years, with hypertension, diabetes and D-Dimer values above 3.17 µg/mL, can be considered prognostic factors for developing thrombotic events due to COVID-19. | - |
Descrição: dc.description | School of Dentistry São Paulo State University (UNESP) | - |
Descrição: dc.description | School of Dentistry São Paulo State University (UNESP) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | European Journal of Clinical Investigation | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | COVID-19 | - |
Palavras-chave: dc.subject | D-dimer | - |
Palavras-chave: dc.subject | meta-analysis | - |
Palavras-chave: dc.subject | prognostic factors | - |
Palavras-chave: dc.subject | SARS-CoV-2 | - |
Palavras-chave: dc.subject | systematic review | - |
Palavras-chave: dc.subject | thrombosis | - |
Título: dc.title | COVID-19 (SARS-CoV-2) infection and thrombotic conditions: A systematic review and meta-analysis | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
O Portal eduCAPES é oferecido ao usuário, condicionado à aceitação dos termos, condições e avisos contidos aqui e sem modificações. A CAPES poderá modificar o conteúdo ou formato deste site ou acabar com a sua operação ou suas ferramentas a seu critério único e sem aviso prévio. Ao acessar este portal, você, usuário pessoa física ou jurídica, se declara compreender e aceitar as condições aqui estabelecidas, da seguinte forma: