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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | University of Coimbra | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Nursing School of Coimbra (ESEnfC) | - |
Autor(es): dc.contributor | University of Orléans | - |
Autor(es): dc.creator | Chupel, Matheus Uba | - |
Autor(es): dc.creator | Minuzzi, Luciele Guerra [UNESP] | - |
Autor(es): dc.creator | Furtado, Guilherme Eustáquio | - |
Autor(es): dc.creator | Santos, Mário Leonardo | - |
Autor(es): dc.creator | Ferreira, José Pedro | - |
Autor(es): dc.creator | Filaire, Edith | - |
Autor(es): dc.creator | Teixeira, Ana Maria | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:45:35Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:45:35Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-03-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1007/s00726-021-02952-6 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/205883 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/205883 | - |
Descrição: dc.description | Immunosenescence contributes to cognitive impairment and neurodegeneration, and those conditions could be attenuated by non-pharmacological anti-inflammatory strategies, such as exercise and supplementation with the amino acid taurine. Since taurine body content decreases with aging, we investigated the effects of supplementation (alone and combined with exercise) on oxidative stress, extracellular matrix degradation, white blood cells, neurotrophins, cognition and physical fitness of elderly women. Forty-eight women (83.58 ± 6.98 years) were enrolled into exercise training only (EO: n = 13), taurine supplementation (TS: n = 12), exercise training + taurine supplementation (ETTS: n = 11), and control group (CG: n = 12). All interventions lasted 14 weeks. Exercise was applied twice a week, and taurine was given once a day (1.5 g). Data collection occurred before and after interventions with the determination of myeloperoxidase (MPO), matrix metalloproteinase-9 (MMP-9), brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) levels, and white blood cell counts (WBC). Montreal cognitive assessment (MoCA) and physical fitness tests were also evaluated. Concentration of MPO and MMP-9 decreased after intervention in TS (p < 0.05). No effect of time or time × group was observed for WBC parameters; however, univariate analysis showed a significant decrease in lymphocytes for TS, while an increase in monocytes occurred in the CG (p < 0.05). MoCA scores decreased over time in the CG (p < 0.05). Improvements in physical fitness occurred in ETTS (better agility and aerobic capacity), mostly likely due to exercise and boosted by taurine supplementation. No changes in BDNF levels were observed (p > 0.05), while NGF concentration were undetectable in almost subjects. Exercise together with taurine supplementation appears to be a valuable strategy to enhance health-related outcomes in older persons. | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Fundação para a Ciência e a Tecnologia | - |
Descrição: dc.description | Faculty of Sport Science and Physical Education Research Center for Sport and Physical Activity CIDAF University of Coimbra | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Universidade Estadual Paulista (UNESP) | - |
Descrição: dc.description | Health Sciences Research Unit: Nursing (UICISA:E) Nursing School of Coimbra (ESEnfC) | - |
Descrição: dc.description | CIAMS Laboratory EA 4532 University of Paris-Sud University of Orléans | - |
Descrição: dc.description | Exercise and Immunometabolism Research Group Universidade Estadual Paulista (UNESP) | - |
Descrição: dc.description | CAPES: 11929-13/8 | - |
Descrição: dc.description | CAPES: 13642-13/8 | - |
Descrição: dc.description | CAPES: 1417/3-4 | - |
Descrição: dc.description | Fundação para a Ciência e a Tecnologia: PTDC/DTP-DES/0154/2012 | - |
Formato: dc.format | 333-345 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Amino Acids | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Aging | - |
Palavras-chave: dc.subject | Cognition | - |
Palavras-chave: dc.subject | Exercise | - |
Palavras-chave: dc.subject | Immunity | - |
Palavras-chave: dc.subject | Oxidative stress | - |
Palavras-chave: dc.subject | Taurine | - |
Título: dc.title | Taurine supplementation reduces myeloperoxidase and matrix-metalloproteinase-9 levels and improves the effects of exercise in cognition and physical fitness in older women | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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