The effect of the Mediterranean Diet on lifespan: A treatment-effect survival analysis of a population-based prospective cohort study in Southern Italy

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorNational Institute of Gastroenterology S de Bellis Research Hospital-
Autor(es): dc.contributorNational Institute of Gastroenterology S de Bellis' Research Hospital-
Autor(es): dc.contributorUniversity of Bari-
Autor(es): dc.contributorUniversidad Nacional de Córdoba-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorCampanella, Angelo-
Autor(es): dc.creatorMisciagna, Giovanni-
Autor(es): dc.creatorMirizzi, Antonella-
Autor(es): dc.creatorCaruso, Maria Gabriella-
Autor(es): dc.creatorBonfiglio, Caterina-
Autor(es): dc.creatorAballay, Laura R-
Autor(es): dc.creatorVas De Arruda Silveira, Liciana [UNESP]-
Autor(es): dc.creatorBianco, Antonella-
Autor(es): dc.creatorFranco, Isabella-
Autor(es): dc.creatorSorino, Paolo-
Autor(es): dc.creatorBuongiorno, Claudia-
Autor(es): dc.creatorCisternino, Anna Maria-
Autor(es): dc.creatorNotarnicola, Maria-
Autor(es): dc.creatorGuerra, Vito M. B-
Autor(es): dc.creatorOsella, Alberto R-
Data de aceite: dc.date.accessioned2022-02-22T00:45:06Z-
Data de disponibilização: dc.date.available2022-02-22T00:45:06Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1093/ije/dyaa222-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205719-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205719-
Descrição: dc.descriptionBackground: The Mediterranean diet (MedDiet) is associated with good health. We aimed to estimate the effect of levels of adherence to the MedDiet on lifespan by performing treatment effects survival analysis. Methods: A sample of 5250 subjects aged ≥18 years were randomly selected from the electoral list of Castellana Grotte and Putignano (Apulian Region, Italy). Cohorts were enrolled in 2005-06 and followed-up until December 2018. The adherence to the MedDiet was measured by the relative Mediterranean score (rMED) and categorized as high, medium and low. Time-to-death (all-causes) as estimated by average treatment effect on the treated (ATET), potential outcome mean (POM) and relative efficiency of exposure were the outcomes. Results: A total of 4896 subjects were included. The median follow-up time was 12.82 (inter quartile range (IQR) 12.22-13.05), 12.91 (IQR 12.21-13.27) and 12.84 (IQR 12.19-13.03) years for high, medium and low rMED subjects respectively. By December 2018, 453 (9.25%) had died. There was a strong effect of medium and low rMED {ATET, -5.10 [95% confidence interval (CI) -9.39, -0.80] and -8.91 (95%CI -13.37, -4.45), respectively}. High rMED has an important effect on mean age at death [POM 90.16 (95% CI 86.06, 94.25)]. The relative effect size for medium and low rMED subjects was a lower lifespan of 5.62% (95% CI 1.01, 10.3) and 9.90% (95% CI 5.30, 5.30), respectively. Conclusions: We observed an important benefit in additional years of survival from adherence to MedDiet in this southern Italian cohort. Further investigation corroborating our findings in other population groups in other geographic regions will be an important contribution to promoting health and longevity.-
Descrição: dc.descriptionLaboratory of Epidemiology and Biostatistics National Institute of Gastroenterology S de Bellis Research Hospital-
Descrição: dc.descriptionClinical Nutrition Outpatients Clinic National Institute of Gastroenterology S de Bellis' Research Hospital-
Descrição: dc.descriptionScientific and Ethical Committee Polyclinic Hospital University of Bari-
Descrição: dc.descriptionLaboratory of Nutritional Biochemistry National Institute of Gastroenterology S de Bellis Research Hospital-
Descrição: dc.descriptionHuman Nutrition Research Center (CenINH) School of Nutrition Faculty of Medical Sciences Universidad Nacional de Córdoba-
Descrição: dc.descriptionDepartment of Biostatistics Bioscience Institute (UNESP)-
Descrição: dc.descriptionDepartment of Biostatistics Bioscience Institute (UNESP)-
Formato: dc.format245-255-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Epidemiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAverage treatment effect on the treated-
Palavras-chave: dc.subjectLifespan-
Palavras-chave: dc.subjectMediterranean diet score-
Palavras-chave: dc.subjectPotential outcome mean-
Palavras-chave: dc.subjectProspective cohort study-
Palavras-chave: dc.subjectTreatment effects survival analysis-
Título: dc.titleThe effect of the Mediterranean Diet on lifespan: A treatment-effect survival analysis of a population-based prospective cohort study in Southern Italy-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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