Evaluation of the aesthetic effect, enamel microhardness and trans-amelodentinal cytotoxicity of a new bleaching agent for professional use containing trimetaphosphate and fluoride

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversity of Ribeirão Preto - UNAERP-
Autor(es): dc.creatorFelipe Akabane, Sara Tiemi [UNESP]-
Autor(es): dc.creatorDanelon, Marcelle [UNESP]-
Autor(es): dc.creatorNunes, Gabriel Pereira [UNESP]-
Autor(es): dc.creatorGruba, Amanda Scarpin [UNESP]-
Autor(es): dc.creatorAlberto de Souza-Costa, Carlos [UNESP]-
Autor(es): dc.creatorCaroline de Oliveira Duque, Carla [UNESP]-
Autor(es): dc.creatorde Oliveira Gallinari, Marjorie [UNESP]-
Autor(es): dc.creatorFraga Briso, André Luiz [UNESP]-
Autor(es): dc.creatorBotazzo Delbem, Alberto Carlos [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:44:46Z-
Data de disponibilização: dc.date.available2022-02-22T00:44:46Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jmbbm.2020.104225-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205594-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205594-
Descrição: dc.descriptionThis study evaluated the effects of calcium gluconate (CaGlu), sodium fluoride (NaF), sodium trimetaphosphate (TMP), and NaF/TMP when added to a 35% hydrogen peroxide (H2O2) bleaching gel on the color change, enamel hardness, penetration and cytotoxicity trans-amelodentinal. Bovine enamel/dentin disks (n = 288) were divided according to the bleaching gel: 35% H2O2; 35% H2O2 + 0.05% NaF; 35% H2O2 + 0.25% TMP; 35% H2O2 + 0.05% NaF + 0.25% TMP; 35% H2O2 + 0.1% NaF + 1% TMP and 35% H2O2 + 2% CaGlu. The bleaching gels were applied thrice (40 min/session) at 7-day intervals between each application. Then, the color change, percentage of surface hardness loss (%SH), cross-sectional hardness (ΔKHN), trans-amelodentinal penetration of H2O2, cell viability and morphology (MDPC-23 odontoblast-like cells), alkaline phosphatase activity (ALP) and deposition of mineralization nodules were determined. The data were submitted to ANOVA, followed by the Student-Newman-Keuls test (p < 0.05). All bleaching gels showed significant color changes after treatment (p < 0.001). Mineral loss (%SH and ΔKHN) and H2O2 penetration were lower for 35% H2O2/0.1% NaF/1% TMP; 35% H2O2/2% CaGlu, meanwhile, showed higher values, compared to the other groups (p < 0.001). Cell viability was around 9%, except for the bleaching gel containing 35% H2O2/0.1% NaF/1% TMP with 12.8% (p < 0.05). ALP was higher for groups containing TMP compared to other whitening gels (p < 0.05). The formation of mineralization nodules was greater for gels containing NaF/TMP or CaGlu (p < 0.05). The alterations of cell morphology were intense for all bleaching gels. It was concluded that the addition of NaF/TMP in-office bleaching did not interfere in bleaching efficacy, reduced enamel demineralization, H2O2 penetration and cytotoxicity.-
Descrição: dc.descriptionASCRS Research Foundation-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Preventive and Restorative Dentistry-
Descrição: dc.descriptionSchool of Dentistry University of Ribeirão Preto - UNAERP, Ribeirão Preto-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Physiology and Pathology-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Dental Materials and Prosthodontics-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Preventive and Restorative Dentistry-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Physiology and Pathology-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry Department of Dental Materials and Prosthodontics-
Descrição: dc.descriptionFAPESP: 2018/08769–5-
Descrição: dc.descriptionCAPES: 88881.068437/2014–01-
Idioma: dc.languageen-
Relação: dc.relationJournal of the Mechanical Behavior of Biomedical Materials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCytotoxicity-
Palavras-chave: dc.subjectDemineralization-
Palavras-chave: dc.subjectDental bleaching-
Palavras-chave: dc.subjectDental enamel-
Palavras-chave: dc.subjectFluoride-
Palavras-chave: dc.subjectPhosphate-
Título: dc.titleEvaluation of the aesthetic effect, enamel microhardness and trans-amelodentinal cytotoxicity of a new bleaching agent for professional use containing trimetaphosphate and fluoride-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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