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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Universidade Federal da Bahia (UFBA) | - |
Autor(es): dc.creator | Queiroz, Marcela Borsatto [UNESP] | - |
Autor(es): dc.creator | Torres, Fernanda Ferrari Esteves [UNESP] | - |
Autor(es): dc.creator | Rodrigues, Elisandra Marcia [UNESP] | - |
Autor(es): dc.creator | Viola, Kennia Scapin [UNESP] | - |
Autor(es): dc.creator | Bosso-Martelo, Roberta | - |
Autor(es): dc.creator | Chavez-Andrade, Gisselle Moraima [UNESP] | - |
Autor(es): dc.creator | Guerreiro-Tanomaru, Juliane Maria [UNESP] | - |
Autor(es): dc.creator | Tanomaru-Filho, Mario [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:44:46Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:44:46Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-01-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.dental.2020.11.014 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/205591 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/205591 | - |
Descrição: dc.description | Objective: To evaluate tricalcium silicate-based (TCS) experimental materials, associated with zirconium oxide (ZrO2), calcium tungstate (CaWO4) or niobium oxide (Nb2O5) radiopacifiers, in comparison with MTA Repair HP (Angelus). Methods: Physicochemical tests: setting time, radiopacity, pH and solubility. In vitro assays: cytotoxicity: MTT and Neutral Red – NR; cell bioactivity: alkaline phosphatase activity (ALP), Alzarin red staining (ARS) and real time PCR (qPCR). Antibacterial activity: direct contact on Enterococcus faecalis in the planktonic form. Physicochemical and ARS data were submitted to ANOVA/Tukey tests; antibacterial activity, to Kruskall–Wallis and Dunn tests; MTT, NR, ALP and qPCR were analyzed by ANOVA/Bonferroni tests (α = 0.05). Results: TCS + CaWO4 presented the longest setting time and MTA HP the shortest. Except for TCS, all the materials presented radiopacity above 3 mmAl. The cements had alkaline pH, antibacterial activity, low solubility and no cytotoxic effects. The highest ALP activity occurred in 14 days, especially to TCS, TCS + ZrO2 and TCS + CaWO4. TCS + ZrO2, TCS + Nb2O5 and MTAHP had higher mineralized nodule formation than those of the negative control (NC). After 7 days, there was no difference in mRNA expression for ALP, when compared to NC. However, after 14 days there was no overexpressed ALP mRNA, especially TCS + Nb2O5, in relation to the CN. All the materials presented antimicrobial action. Significance: The pure tricalcium silicate associated with ZrO2, CaWO4 or Nb2O5 had appropriate physicochemical properties, antibacterial activity, cytocompatibility and induced mineralization in Saos-2, indicating their use as reparative materials. | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Department of Restorative Dentistry São Paulo State University (UNESP) School of Dentistry | - |
Descrição: dc.description | Department of Dentistry Bahia Federal University (UFBA) School of Dentistry | - |
Descrição: dc.description | Department of Restorative Dentistry São Paulo State University (UNESP) School of Dentistry | - |
Formato: dc.format | 311-320 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Dental Materials | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Biological properties | - |
Palavras-chave: dc.subject | Calcium silicate | - |
Palavras-chave: dc.subject | Chemical properties | - |
Palavras-chave: dc.subject | Dental materials | - |
Palavras-chave: dc.subject | Endodontics | - |
Palavras-chave: dc.subject | Physical properties | - |
Título: dc.title | Physicochemical, biological, and antibacterial evaluation of tricalcium silicate-based reparative cements with different radiopacifiers | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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