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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Indiana University School of Dentistry | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Tonon, Caroline C. [UNESP] | - |
Autor(es): dc.creator | Panariello, Beatriz H. D. | - |
Autor(es): dc.creator | Spolidorio, Denise M. P. [UNESP] | - |
Autor(es): dc.creator | Gossweiler, Ana G. | - |
Autor(es): dc.creator | Duarte, Simone | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:44:44Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:44:44Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2019-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1002/JPER.20-0333 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/205579 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/205579 | - |
Descrição: dc.description | Background: Removal of dental plaque and local application of local chemical adjuncts, such as chlorhexidine (CHX), have been used to control and treat peri-implant disease. However, these methods can damage the surface properties of the implants or promote bacterial resistance. The application of ozone as an adjunctive treatment represents a new approach in the management of peri-implantitis. Thus, the purpose of this study was to evaluate the antimicrobial effect of ozonized physiological saline solution in different concentrations against oral biofilms developed on titanium surface. Methods: Single and multi-species biofilms of Porphyromonas gingivalis, Fusobacterium nucleatum, and Streptococcus oralis were formed on titanium specimens for 5 days in anaerobic conditions. Biofilms were treated with ozonized saline solution at different concentrations (25, 50, and 80 μg/NmL), for 30 seconds and 1 minute. CHX (0.12%) and saline solution (0.89% NaCl) were used as positive and negative controls, respectively. Bacterial viability was quantified by Colony Forming Units (CFU mL−1), and biofilm images were acquired by Confocal Laser Scanning Microscopy (CLSM). Data were analyzed by parametric test (ANOVA) with Tukey post-hoc test (P < 0.05). Results: Ozonized saline solution showed antibiofilm activity at a concentration of 80 μg/NmL for 30 seconds and 1 minute, reducing, mainly, Porphyromonas gingivalis viability, with 2.78 and 1.7 log10 CFU mL−1 of reduction in both single and multi-specie biofilms, respectively, when compared to the control (saline), whereas CHX reduced 1.4 and 1.2 log10 CFU mL−1. Conclusion: Ozonized saline solution has antibiofilm activity, with better effect when applied for 1 minute at 80 μg/NmL, being a promising candidate therapy for the treatment of peri-implant diseases. | - |
Descrição: dc.description | Department of Cariology Operative Dentistry and Dental Public Health Indiana University School of Dentistry | - |
Descrição: dc.description | Department of Oral Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP) | - |
Descrição: dc.description | Department of Oral Diagnosis and Surgery School of Dentistry São Paulo State University (UNESP) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Journal of Periodontology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | biofilm | - |
Palavras-chave: dc.subject | Fusobacterium nucleatum | - |
Palavras-chave: dc.subject | ozono therapy | - |
Palavras-chave: dc.subject | peri-implantitis | - |
Palavras-chave: dc.subject | Porphyromonas gingivalis | - |
Palavras-chave: dc.subject | Streptococcus oralis | - |
Título: dc.title | Anti-biofilm effect of ozonized physiological saline solution on peri-implant-related biofilm | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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