Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity of East Anglia-
Autor(es): dc.contributorCardiff University-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorJohn Innes Centre-
Autor(es): dc.contributorUniversity of Nottingham-
Autor(es): dc.creatorBell, Ellen A.-
Autor(es): dc.creatorCable, Jo-
Autor(es): dc.creatorOliveira, Claudio [UNESP]-
Autor(es): dc.creatorRichardson, David S.-
Autor(es): dc.creatorYant, Levi-
Autor(es): dc.creatorTaylor, Martin I.-
Data de aceite: dc.date.accessioned2022-02-22T00:44:34Z-
Data de disponibilização: dc.date.available2022-02-22T00:44:34Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/ece3.6987-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205525-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205525-
Descrição: dc.descriptionWhole-genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large-scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune-related toll-like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity.-
Descrição: dc.descriptionSchool of Biological Sciences University of East Anglia-
Descrição: dc.descriptionSchool of Biosciences Cardiff University-
Descrição: dc.descriptionDepartmento de Morfologia Instituto de Biosiências/UNESP-
Descrição: dc.descriptionDepartment of Cell and Developmental Biology John Innes Centre-
Descrição: dc.descriptionFuture Food Beacon of Excellence and the School of Life Sciences University of Nottingham-
Descrição: dc.descriptionDepartmento de Morfologia Instituto de Biosiências/UNESP-
Formato: dc.format13949-13956-
Idioma: dc.languageen-
Relação: dc.relationEcology and Evolution-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectimmunogenetic diversity-
Palavras-chave: dc.subjectinfectious disease-
Palavras-chave: dc.subjectsympatric communities-
Palavras-chave: dc.subjecttoll-like receptors-
Palavras-chave: dc.subjectwhole-genome duplication-
Título: dc.titleHelp or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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