Photochemical persistence of sulfa drugs in aqueous medium: kinetic study and mathematical simulations

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorLastre-Acosta, Arlen Mabel-
Autor(es): dc.creatorCristofoli, Bruno Segawa-
Autor(es): dc.creatorParizi, Marcela Prado Silva [UNESP]-
Autor(es): dc.creatordo Nascimento, Claudio Augusto Oller-
Autor(es): dc.creatorTeixeira, Antonio Carlos Silva Costa-
Data de aceite: dc.date.accessioned2022-02-22T00:44:31Z-
Data de disponibilização: dc.date.available2022-02-22T00:44:31Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s11356-020-11715-x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205506-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205506-
Descrição: dc.descriptionThis study aimed at investigating the photochemical behavior of sulfa drugs containing five and six-membered heterocyclic substituents (sulfamethoxazole (SMX) and sulfadiazine (SDZ), respectively), in an aqueous medium. Despite their importance, studies devoted to the use of photochemical models to predict the environmental phototransformation of pollutants in surface waters, by combining laboratory results and natural aquatic systems parameters, are still scarce in the scientific literature. In this work, the second-order reaction rate constants of SDZ and SMX with hydroxyl radicals (●OH), singlet oxygen (1O2), and triplet excited states of chromophoric dissolved organic matter (3CDOM*) were experimentally determined at pH 7, using the competition kinetics approach. The results show that ●OH and 3CDOM* are the key species involved in sulfonamide degradation, with anionic SMX, most prevalent at pH 6–9, being degraded much slower than the anionic form of SDZ. Moreover, SDZ and SMX photodegradation in natural water samples (spring-fed natural pond, public supply reservoir, and sea water) was significantly enhanced relative to depletion in pure water. Finally, from mathematical simulations of the sunlight-driven sulfonamide degradation, half-life times were predicted for these drugs varying from less than 2 to about 90 days, depending on the water depth, concentration of key species (DOC, HCO3−, NO2−, CO32−) in natural aqueous systems, as well as on the particular heterocyclic substituent.-
Descrição: dc.descriptionResearch Group in Advanced Oxidation Processes (AdOx) Department of Chemical Engineering University of São Paulo, Av. Prof. Luciano Gualberto, tr. 3, 380-
Descrição: dc.descriptionChemical Systems Engineering Center Department of Chemical Engineering University of São Paulo, Av. Prof. Luciano Gualberto, tr. 3, 380-
Descrição: dc.descriptionEnergy Engineering Department São Paulo State University (UNESP), Av. Dos Barrageiros, 1881-
Descrição: dc.descriptionEnergy Engineering Department São Paulo State University (UNESP), Av. Dos Barrageiros, 1881-
Formato: dc.format23887-23895-
Idioma: dc.languageen-
Relação: dc.relationEnvironmental Science and Pollution Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectEnvironmental persistence-
Palavras-chave: dc.subjectMathematical modeling-
Palavras-chave: dc.subjectPhotolysis-
Palavras-chave: dc.subjectReactive photo-induced species (RPS)-
Palavras-chave: dc.subjectReal aqueous matrices-
Palavras-chave: dc.subjectSulfonamides-
Título: dc.titlePhotochemical persistence of sulfa drugs in aqueous medium: kinetic study and mathematical simulations-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.