Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases

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Autor(es): dc.contributorIM Sechenov First Moscow State Medical University (Sechenov University)-
Autor(es): dc.contributorFederal Research Centre of Biological Systems and Agro-technologies of the Russian Academy of Sciences-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorAlbert Einstein College of Medicine-
Autor(es): dc.contributorSun Yat-sen University-
Autor(es): dc.contributorUniversity of Wuppertal-
Autor(es): dc.contributorI.I. Mechnikov North-Western State Medical University-
Autor(es): dc.contributorK.A. Rauhfus Children's City Multidisciplinary Clinical Center for High Medical Technologies-
Autor(es): dc.contributorInnlandet Hospital Trust-
Autor(es): dc.contributorUniversity of Crete-
Autor(es): dc.contributorAristotle University of Thessaloniki-
Autor(es): dc.contributorUniversity School of Advanced Studies IUSS-
Autor(es): dc.contributorYaroslavl State University-
Autor(es): dc.creatorSkalny, Anatoly V.-
Autor(es): dc.creatorLima, Thania Rios Rossi [UNESP]-
Autor(es): dc.creatorKe, Tao-
Autor(es): dc.creatorZhou, Ji-Chang-
Autor(es): dc.creatorBornhorst, Julia-
Autor(es): dc.creatorAlekseenko, Svetlana I.-
Autor(es): dc.creatorAaseth, Jan-
Autor(es): dc.creatorAnesti, Ourania-
Autor(es): dc.creatorSarigiannis, Dimosthenis A.-
Autor(es): dc.creatorTsatsakis, Aristides-
Autor(es): dc.creatorAschner, Michael-
Autor(es): dc.creatorTinkov, Alexey A.-
Data de aceite: dc.date.accessioned2022-02-22T00:44:09Z-
Data de disponibilização: dc.date.available2022-02-22T00:44:09Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.fct.2020.111809-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205374-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205374-
Descrição: dc.descriptionMultiple medical, lifestyle, and environmental conditions, including smoking and particulate pollution, have been considered as risk factors for COronaVIrus Disease 2019 (COVID-19) susceptibility and severity. Taking into account the high level of toxic metals in both particulate matter (PM2.5) and tobacco smoke, the objective of this review is to discuss recent data on the role of heavy metal exposure in development of respiratory dysfunction, immunotoxicity, and severity of viral diseases in epidemiological and experimental studies, as to demonstrate the potential crossroads between heavy metal exposure and COVID-19 severity risk. The existing data demonstrate that As, Cd, Hg, and Pb exposure is associated with respiratory dysfunction and respiratory diseases (COPD, bronchitis). These observations corroborate laboratory findings on the role of heavy metal exposure in impaired mucociliary clearance, reduced barrier function, airway inflammation, oxidative stress, and apoptosis. The association between heavy metal exposure and severity of viral diseases, including influenza and respiratory syncytial virus has been also demonstrated. The latter may be considered a consequence of adverse effects of metal exposure on adaptive immunity. Therefore, reduction of toxic metal exposure may be considered as a potential tool for reducing susceptibility and severity of viral diseases affecting the respiratory system, including COVID-19.-
Descrição: dc.descriptionMinistry of Science and Higher Education of the Russian Federation-
Descrição: dc.descriptionDeutsche Forschungsgemeinschaft-
Descrição: dc.descriptionNational Institute of Environmental Health Sciences-
Descrição: dc.descriptionIM Sechenov First Moscow State Medical University (Sechenov University)-
Descrição: dc.descriptionFederal Research Centre of Biological Systems and Agro-technologies of the Russian Academy of Sciences-
Descrição: dc.descriptionSão Paulo State University - UNESP Center for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Descrição: dc.descriptionDepartment of Molecular Pharmacology Albert Einstein College of Medicine-
Descrição: dc.descriptionSchool of Public Health (Shenzhen) Sun Yat-sen University-
Descrição: dc.descriptionFood Chemistry Faculty of Mathematics and Natural Sciences University of Wuppertal-
Descrição: dc.descriptionI.I. Mechnikov North-Western State Medical University-
Descrição: dc.descriptionK.A. Rauhfus Children's City Multidisciplinary Clinical Center for High Medical Technologies-
Descrição: dc.descriptionResearch Department Innlandet Hospital Trust-
Descrição: dc.descriptionLaboratory of Toxicology Medical School University of Crete, Voutes-
Descrição: dc.descriptionHERACLES Research Center on the Exposome and Health Center for Interdisciplinary Research and Innovation Aristotle University of Thessaloniki-
Descrição: dc.descriptionUniversity School of Advanced Studies IUSS-
Descrição: dc.descriptionYaroslavl State University-
Descrição: dc.descriptionSão Paulo State University - UNESP Center for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Descrição: dc.descriptionMinistry of Science and Higher Education of the Russian Federation: 0856-2020-00082-
Descrição: dc.descriptionDeutsche Forschungsgemeinschaft: FOR 2558-
Descrição: dc.descriptionNational Institute of Environmental Health Sciences: R01ES07331-
Descrição: dc.descriptionNational Institute of Environmental Health Sciences: R01ES105633-
Idioma: dc.languageen-
Relação: dc.relationFood and Chemical Toxicology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectArsenic-
Palavras-chave: dc.subjectCadmium-
Palavras-chave: dc.subjectImmunity-
Palavras-chave: dc.subjectLead-
Palavras-chave: dc.subjectMercury-
Título: dc.titleToxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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