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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | IM Sechenov First Moscow State Medical University (Sechenov University) | - |
Autor(es): dc.contributor | Federal Research Centre of Biological Systems and Agro-technologies of the Russian Academy of Sciences | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Albert Einstein College of Medicine | - |
Autor(es): dc.contributor | Sun Yat-sen University | - |
Autor(es): dc.contributor | University of Wuppertal | - |
Autor(es): dc.contributor | I.I. Mechnikov North-Western State Medical University | - |
Autor(es): dc.contributor | K.A. Rauhfus Children's City Multidisciplinary Clinical Center for High Medical Technologies | - |
Autor(es): dc.contributor | Innlandet Hospital Trust | - |
Autor(es): dc.contributor | University of Crete | - |
Autor(es): dc.contributor | Aristotle University of Thessaloniki | - |
Autor(es): dc.contributor | University School of Advanced Studies IUSS | - |
Autor(es): dc.contributor | Yaroslavl State University | - |
Autor(es): dc.creator | Skalny, Anatoly V. | - |
Autor(es): dc.creator | Lima, Thania Rios Rossi [UNESP] | - |
Autor(es): dc.creator | Ke, Tao | - |
Autor(es): dc.creator | Zhou, Ji-Chang | - |
Autor(es): dc.creator | Bornhorst, Julia | - |
Autor(es): dc.creator | Alekseenko, Svetlana I. | - |
Autor(es): dc.creator | Aaseth, Jan | - |
Autor(es): dc.creator | Anesti, Ourania | - |
Autor(es): dc.creator | Sarigiannis, Dimosthenis A. | - |
Autor(es): dc.creator | Tsatsakis, Aristides | - |
Autor(es): dc.creator | Aschner, Michael | - |
Autor(es): dc.creator | Tinkov, Alexey A. | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:44:09Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:44:09Z | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2021-06-25 | - |
Data de envio: dc.date.issued | 2020-11-30 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.fct.2020.111809 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/205374 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/205374 | - |
Descrição: dc.description | Multiple medical, lifestyle, and environmental conditions, including smoking and particulate pollution, have been considered as risk factors for COronaVIrus Disease 2019 (COVID-19) susceptibility and severity. Taking into account the high level of toxic metals in both particulate matter (PM2.5) and tobacco smoke, the objective of this review is to discuss recent data on the role of heavy metal exposure in development of respiratory dysfunction, immunotoxicity, and severity of viral diseases in epidemiological and experimental studies, as to demonstrate the potential crossroads between heavy metal exposure and COVID-19 severity risk. The existing data demonstrate that As, Cd, Hg, and Pb exposure is associated with respiratory dysfunction and respiratory diseases (COPD, bronchitis). These observations corroborate laboratory findings on the role of heavy metal exposure in impaired mucociliary clearance, reduced barrier function, airway inflammation, oxidative stress, and apoptosis. The association between heavy metal exposure and severity of viral diseases, including influenza and respiratory syncytial virus has been also demonstrated. The latter may be considered a consequence of adverse effects of metal exposure on adaptive immunity. Therefore, reduction of toxic metal exposure may be considered as a potential tool for reducing susceptibility and severity of viral diseases affecting the respiratory system, including COVID-19. | - |
Descrição: dc.description | Ministry of Science and Higher Education of the Russian Federation | - |
Descrição: dc.description | Deutsche Forschungsgemeinschaft | - |
Descrição: dc.description | National Institute of Environmental Health Sciences | - |
Descrição: dc.description | IM Sechenov First Moscow State Medical University (Sechenov University) | - |
Descrição: dc.description | Federal Research Centre of Biological Systems and Agro-technologies of the Russian Academy of Sciences | - |
Descrição: dc.description | São Paulo State University - UNESP Center for Evaluation of Environmental Impact on Human Health (TOXICAM) | - |
Descrição: dc.description | Department of Molecular Pharmacology Albert Einstein College of Medicine | - |
Descrição: dc.description | School of Public Health (Shenzhen) Sun Yat-sen University | - |
Descrição: dc.description | Food Chemistry Faculty of Mathematics and Natural Sciences University of Wuppertal | - |
Descrição: dc.description | I.I. Mechnikov North-Western State Medical University | - |
Descrição: dc.description | K.A. Rauhfus Children's City Multidisciplinary Clinical Center for High Medical Technologies | - |
Descrição: dc.description | Research Department Innlandet Hospital Trust | - |
Descrição: dc.description | Laboratory of Toxicology Medical School University of Crete, Voutes | - |
Descrição: dc.description | HERACLES Research Center on the Exposome and Health Center for Interdisciplinary Research and Innovation Aristotle University of Thessaloniki | - |
Descrição: dc.description | University School of Advanced Studies IUSS | - |
Descrição: dc.description | Yaroslavl State University | - |
Descrição: dc.description | São Paulo State University - UNESP Center for Evaluation of Environmental Impact on Human Health (TOXICAM) | - |
Descrição: dc.description | Ministry of Science and Higher Education of the Russian Federation: 0856-2020-00082 | - |
Descrição: dc.description | Deutsche Forschungsgemeinschaft: FOR 2558 | - |
Descrição: dc.description | National Institute of Environmental Health Sciences: R01ES07331 | - |
Descrição: dc.description | National Institute of Environmental Health Sciences: R01ES105633 | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Food and Chemical Toxicology | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Arsenic | - |
Palavras-chave: dc.subject | Cadmium | - |
Palavras-chave: dc.subject | Immunity | - |
Palavras-chave: dc.subject | Lead | - |
Palavras-chave: dc.subject | Mercury | - |
Título: dc.title | Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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