Curcuma longa L. helps macrophages to control opportunistic micro-organisms during host-microbe interactions

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorAnhembi Morumbi University-
Autor(es): dc.contributorAnhanguera University-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversity of Florida-
Autor(es): dc.creatorW Figueira, Leandro [UNESP]-
Autor(es): dc.creatorDe Oliveira, Jonatas R. [UNESP]-
Autor(es): dc.creatorNetto, Amandio A.L.-
Autor(es): dc.creatorS Zamarioli, Lucas Dos-
Autor(es): dc.creatorMarcucci, Maria C.-
Autor(es): dc.creatorCamargo, Samira E.A.-
Autor(es): dc.creatorDe Oliveira, Luciane D. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:44:01Z-
Data de disponibilização: dc.date.available2022-02-22T00:44:01Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2020-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.2217/fmb-2019-0297-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205316-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205316-
Descrição: dc.descriptionAim: Plant products have been evaluated to control opportunistic micro-organisms, as well as fortify immune system cells. Thus, Curcuma longa L. (turmeric) extract was evaluated in interactions of murine macrophages (RAW 264.7) with Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans, in order to establish cooperation with defense cells. Materials & methods: Effects of minimal inhibitory concentrations (MIC) of the plant extract were analyzed on phagocytosis, cell viability of RAW 264.7 and production of inflammation-related molecules (IL-1β, TNF-α, IL-10 and NO). Results: The plant extract was cytocompatible and promoted significant reductions of micro-organisms, and synthesis of inflammation-related molecules, during interactions. Conclusion: C. longa L. extract showed significant antimicrobial response and cooperation with macrophages, by fighting bacteria and yeasts during host-microbe interactions.-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University (UNESP) Institute of Science and Technology, Av. Engenheiro Francisco José Longo, 777-
Descrição: dc.descriptionSchool of Medicine Anhembi Morumbi University, Av. Dep. Benedito Matarazzo, 4050-
Descrição: dc.descriptionAnhanguera University, Av. Raimundo Pereira de Magalhães, 3305-
Descrição: dc.descriptionDepartment of Mode of Drug Action Federal University of São Paulo (UNIFESP) Institute of Pharmacology and Molecular Biology, Rua Três de Maio, 100-
Descrição: dc.descriptionDepartment of Restorative Dental Sciences College of Dentistry University of Florida, 1395 Center Drive-
Descrição: dc.descriptionDepartment of Biosciences and Oral Diagnosis São Paulo State University (UNESP) Institute of Science and Technology, Av. Engenheiro Francisco José Longo, 777-
Formato: dc.format1237-1248-
Idioma: dc.languageen-
Relação: dc.relationFuture Microbiology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectCurcuma longa L.-
Palavras-chave: dc.subjecthost-microbe interaction-
Palavras-chave: dc.subjectmacrophages-
Palavras-chave: dc.subjectPseudomonas aeruginosa-
Palavras-chave: dc.subjectRAW 264.7-
Palavras-chave: dc.subjectStaphylococcus aureus-
Título: dc.titleCurcuma longa L. helps macrophages to control opportunistic micro-organisms during host-microbe interactions-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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