Schinus terebinthifolius (Brazilian peppertree) extract used as antifungal to control candida spp. in planktonic cultures and biofilms

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Autor(es): dc.contributorUniversidade Federal do Rio de Janeiro (UFRJ)-
Autor(es): dc.contributorBasic Institute of Biosciences-
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorBrazcubas Faculty of Dentistry-
Autor(es): dc.contributorSchool of Medicine-
Autor(es): dc.creatorViegas, Daiane de Jesus-
Autor(es): dc.creatorAmêndola, Isabela-
Autor(es): dc.creatorBotrel, Tássia Marchetti [UNESP]-
Autor(es): dc.creatorde OLIVEIRA, Felipe Eduardo-
Autor(es): dc.creatorFigueira, Leandro Wagner [UNESP]-
Autor(es): dc.creatorSper, Fábia Lugli [UNESP]-
Autor(es): dc.creatorde OLIVEIRA, Jonatas Rafael-
Autor(es): dc.creatorde OLIVEIRA, Luciane Dias [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:43:52Z-
Data de disponibilização: dc.date.available2022-02-22T00:43:52Z-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2021-06-25-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.14295/bds.2020.v23i4.2077-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/205261-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/205261-
Descrição: dc.descriptionObjective: The use of medicinal plants may be an alternative method for the control of Candida spp. responsible for human infections. This study evaluated the antifungal effect of Schinus terebinthifolius extract (Brazilian Peppertree) on C. albicans, C. dubliniensis, C. glabrata, and C. krusei planktonic cultures and biofilms. Material and Methods: Minimum inhibitory concentration (MIC) and minimum fungal concentration (MFC) of the plant extract were determined by the broth microdilution method. Biofilms formed in microplate wells were exposed to the extract for 5 min (50, 100 and 200 mg/mL) or 24 h (25, 50 and 100 mg/mL). After determination of colony-forming units per milliliter (CFU/mL), the data were analyzed by one-way ANOVA and Tukey’s Test (P ≤ 0.05). Results: Different MIC (mg/mL) were found, such as 0.39 (C. dubliniensis), 1.56 (C. albicans), and 3.13 (C. glabrata and C. krusei). Besides, MFC (mg/mL) of 0.78 (C. dubliniensis) and 3.13 (C. albicans, C. glabrata and C. krusei) were also observed. Regarding the biofilms, significant reductions (log10) were found after 5 min and 24 h exposure to the plant extract, compared to the control group. However, C. dubliniensis was significantly affected only in 24 h treatment. Conclusion: S. terebinthifolius extract presented a significant antifungal effect on C. albicans, C. dubliniensis, C. glabrata, and C. Krusei both in planktonic cultures and biofilms.-
Descrição: dc.descriptionFederal University of Rio de Janeiro (UFRJ) Institute of Biodiversity and Sustainability (NUPEM)-
Descrição: dc.descriptionUniversity of Taubaté (UNITAU) Basic Institute of Biosciences-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Science and Technology-
Descrição: dc.descriptionUniversity Center Brazcubas Brazcubas Faculty of Dentistry-
Descrição: dc.descriptionAnhembi Morumbi University School of Medicine-
Descrição: dc.descriptionSão Paulo State University (UNESP) Institute of Science and Technology-
Formato: dc.format1-7-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Dental Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiofilms-
Palavras-chave: dc.subjectBrazilian peppertree-
Palavras-chave: dc.subjectCandida-
Palavras-chave: dc.subjectPlanktonic cultures-
Palavras-chave: dc.subjectSchinus terebinthifolius-
Título: dc.titleSchinus terebinthifolius (Brazilian peppertree) extract used as antifungal to control candida spp. in planktonic cultures and biofilms-
Título: dc.titleExtrato de schinus terebinthifolius (Pimenta rosa) utilizado como antifúngico para controlar candida spp. em culturas planctônicas e biofilmes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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