Spliced genes in muscle from Nelore Cattle and their association with carcass and meat quality

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorNational Council for Scientific and Technological Development (CNPq)-
Autor(es): dc.contributorUniversity of Missouri Columbia-
Autor(es): dc.creatorSilva, Danielly B. S. [UNESP]-
Autor(es): dc.creatorFonseca, Larissa F. S. [UNESP]-
Autor(es): dc.creatorPinheiro, Daniel G. [UNESP]-
Autor(es): dc.creatorMagalhães, Ana F. B. [UNESP]-
Autor(es): dc.creatorMuniz, Maria M. M. [UNESP]-
Autor(es): dc.creatorFerro, Jesus A. [UNESP]-
Autor(es): dc.creatorBaldi, Fernando [UNESP]-
Autor(es): dc.creatorChardulo, Luis A. L. [UNESP]-
Autor(es): dc.creatorSchnabel, Robert D.-
Autor(es): dc.creatorTaylor, Jeremy F.-
Autor(es): dc.creatorAlbuquerque, Lucia G. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:35:21Z-
Data de disponibilização: dc.date.available2022-02-22T00:35:21Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-020-71783-4-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/202072-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/202072-
Descrição: dc.descriptionTranscript data obtained by RNA-Seq were used to identify differentially expressed alternatively spliced genes in ribeye muscle tissue between Nelore cattle that differed in their ribeye area (REA) or intramuscular fat content (IF). A total of 166 alternatively spliced transcripts from 125 genes were significantly differentially expressed in ribeye muscle between the highest and lowest REA groups (p ≤ 0.05). For animals selected on their IF content, 269 alternatively spliced transcripts from 219 genes were differentially expressed in ribeye muscle between the highest and lowest IF animals. Cassette exons and alternative 3′ splice sites were the most frequently found alternatively spliced transcripts for REA and IF content. For both traits, some differentially expressed alternatively spliced transcripts belonged to myosin and myotilin gene families. The hub transcripts were identified for REA (LRRFIP1, RCAN1 and RHOBTB1) and IF (TRIP12, HSPE1 and MAP2K6) have an important role to play in muscle cell degradation, development and motility. In general, transcripts were found for both traits with biological process GO terms that were involved in pathways related to protein ubiquitination, muscle differentiation, lipids and hormonal systems. Our results reinforce the biological importance of these known processes but also reveal new insights into the complexity of the whole cell muscle mRNA of Nelore cattle.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionNational Council for Scientific and Technological Development (CNPq)-
Descrição: dc.descriptionSchool of Veterinary and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionDivision of Animal Sciences University of Missouri Columbia-
Descrição: dc.descriptionSchool of Agricultural and Veterinarian Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionSchool of Veterinary and Animal Science São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleSpliced genes in muscle from Nelore Cattle and their association with carcass and meat quality-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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