Metarhizium anisopliae conidia production in packed-bed bioreactor using rice as substrate in successive cultivations

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorda Cunha, Lucas Portilho [UNESP]-
Autor(es): dc.creatorCasciatori, Fernanda Perpétua-
Autor(es): dc.creatorVicente, Isabela Valente [UNESP]-
Autor(es): dc.creatorGarcia, Renata Laurito [UNESP]-
Autor(es): dc.creatorThoméo, João Cláudio [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:34:56Z-
Data de disponibilização: dc.date.available2022-02-22T00:34:56Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.procbio.2020.07.002-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201935-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201935-
Descrição: dc.descriptionThis paper presents a study on scale-up and cost reduction of the production of spores of Metarhizium anisopliae IBCB 425, entomopathogenic fungus used in sugarcane crops. Rice was mixed with sugarcane bagasse (9:1 w/w) for substrate composition, assuring adequate physical structure for cultivation in packed-beds. Spores yield from only rice in bench-scale packed-bed bioreactor was 56 % of the one obtained from the mixture 9:1 w/w. In comparison to plastic packages used in bioindustries, equivalent spores yields per gram of substrate have been achieved in bench and pilot-scale bioreactors built by cylindrical jacketed modules, that provide better control of operational and environmental variables, attested by little variability among replicates. Although non-negligible temperature rise (5 °C above the ideal) occurred within the pilot-scale bioreactor, spores production was not harmed in comparison to bench-scale. By reusing rice up to three successive cultivations, a 2.5-fold increase of spores yields was achieved in comparison to single use. Temperatures and CO2 profiles corroborates the fungus adapted differently to substrate at each usage. Such results are valuable for industrial producers of commercial formulations of the fungus spores, allowing process modernization by using packed-bed bioreactors and production costs and rice demand reduction by recycling the substrate.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionGraduate Program in Food Engineering and Science Food Engineering and Technology Department Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP), Cristóvão Colombo 2265, Jardim Nazareth-
Descrição: dc.descriptionGraduate Program in Chemical Engineering Chemical Engineering Department Center of Exact Sciences and of Technology Federal University of São Carlos (UFSCar), Rod. Washington Luiz km 235 SP 310, Bairro Monjolinho-
Descrição: dc.descriptionGraduate Program in Food Engineering and Science Food Engineering and Technology Department Institute of Biosciences Letters and Exact Sciences São Paulo State University (UNESP), Cristóvão Colombo 2265, Jardim Nazareth-
Descrição: dc.descriptionFAPESP: 2010/12624-0-
Descrição: dc.descriptionFAPESP: 2014/23453-3-
Descrição: dc.descriptionFAPESP: 2018/00996-2-
Descrição: dc.descriptionCNPq: 430786/2018-2-
Formato: dc.format104-111-
Idioma: dc.languageen-
Relação: dc.relationProcess Biochemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiocontrol-
Palavras-chave: dc.subjectScale-up-
Palavras-chave: dc.subjectSolid-state fermentation-
Palavras-chave: dc.subjectSugarcane crops-
Título: dc.titleMetarhizium anisopliae conidia production in packed-bed bioreactor using rice as substrate in successive cultivations-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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