Cytoprotective and anti-apoptotic action of HSP70 stress protein in Oreochromis niloticus exposed to residual dilutions of insecticides with fipronil and ethiprole

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorGuedes, Thays de Andrade [UNESP]-
Autor(es): dc.creatorMoreira-de-Sousa, Cristina [UNESP]-
Autor(es): dc.creatorLima, Hellen Maria Soares [UNESP]-
Autor(es): dc.creatorGrella, Tatiane Caroline [UNESP]-
Autor(es): dc.creatorSocolowski, Priscila Cintra [UNESP]-
Autor(es): dc.creatorFontanetti, Carmem Silvia [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:34:33Z-
Data de disponibilização: dc.date.available2022-02-22T00:34:33Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-08-02-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/03601234.2020.1766898-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201806-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201806-
Descrição: dc.descriptionThe objective of this research was to investigate the potential damage caused by the residual concentrations of the insecticides Regent® WS 800 and Curbix® SC 200, containing fipronil and ethiprole, respectively as active ingredients, on the liver of Oreochromis niloticus. The analyses of HSP70 shock protein labelling and cell death process by TUNEL method were performed in order to measure the effects of the exposure of cell repair system of fish to both insecticides. Statistical analyses showed no significant molecular damage to the hepatic tissue of animals. Nevertheless, variations in HSP70 and DNA fragmentation levels, endpoint of cell repair system response and cellular death, respectively, were observed in several groups. These results indicate that the cell repair machinery was efficient when in contact with residual concentrations of insecticides. However, the DNA fragmentation detected by the TUNEL method suggests that even in face of the cytoprotective action of the HSP70 protein, there are damages that become irreparable. To finish, it is worth mentioning that given the results obtained from residual concentrations, use in the field should be with caution.-
Descrição: dc.descriptionDepartment of Biology UNESP (São Paulo State University) IB (Instituto de Biociências)-
Descrição: dc.descriptionDepartment of Biology UNESP (São Paulo State University) IB (Instituto de Biociências)-
Formato: dc.format687-693-
Idioma: dc.languageen-
Relação: dc.relationJournal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectimmunostaining-
Palavras-chave: dc.subjectphenylpyrazole-
Palavras-chave: dc.subjectStress protein-
Palavras-chave: dc.subjectTilápia-
Palavras-chave: dc.subjectTUNEL-
Título: dc.titleCytoprotective and anti-apoptotic action of HSP70 stress protein in Oreochromis niloticus exposed to residual dilutions of insecticides with fipronil and ethiprole-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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