Mineral preference in rats treated with muscimol into the lateral parabrachial nucleus

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.creatorCallera, João Carlos [UNESP]-
Autor(es): dc.creatorDe Luca, Laurival Antonio [UNESP]-
Autor(es): dc.creatorMenani, José Vanderlei [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:34:23Z-
Data de disponibilização: dc.date.available2022-02-22T00:34:23Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-07-13-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.neulet.2020.134989-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201737-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201737-
Descrição: dc.descriptionInjection of muscimol, a GABAA receptor agonist, into the lateral parabrachial nucleus (LPBN) induces 0.3 M NaCl intake in rats. In the present work, we investigated whether such an effect applies to hypertonic (0.3 M) mineral solutions in general or is selective to sodium solutions in a 240 min intake test. Muscimol injection (0.5 nmol/0.2 μL) compared to vehicle injection into the LPBN of adult hydrated rats produced a preferential ingestion of 0.3 M NaCl (25.3 ± 10.2 mL) followed by a 0.3 M NaHCO3 intake (11.7 ± 5.6 mL), with no significant effect on water, KCl and CaCl2 intake. Only the effect of muscimol on NaCl intake (19.0 ± 10.4 mL) persisted in cell-dehydrated rats, with hardly any effect on water or other mineral solutions. The results suggest that the LPBN controls the ingestion of hypertonic NaCl and NaHCO3. They also suggest a selective mechanisms involving the LPBN to check hypertonic sodium intake.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Basic Sciences School of Dentistry Sao Paulo State University (UNESP), Rodovia Marechal Rondom, Km 527-
Descrição: dc.descriptionDepartment of Physiology and Pathology School of Dentistry UNESP-
Descrição: dc.descriptionDepartment of Basic Sciences School of Dentistry Sao Paulo State University (UNESP), Rodovia Marechal Rondom, Km 527-
Descrição: dc.descriptionDepartment of Physiology and Pathology School of Dentistry UNESP-
Idioma: dc.languageen-
Relação: dc.relationNeuroscience Letters-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBicarbonate-
Palavras-chave: dc.subjectDehydration-
Palavras-chave: dc.subjectFluid intake-
Palavras-chave: dc.subjectGABA-
Palavras-chave: dc.subjectParabrachial nucleus-
Palavras-chave: dc.subjectReceptors-
Palavras-chave: dc.subjectSodium appetite-
Título: dc.titleMineral preference in rats treated with muscimol into the lateral parabrachial nucleus-
Tipo de arquivo: dc.typelivro digital-
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