Laser surgery in management of medication-related osteonecrosis of the jaws: a meta-analysis

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorSacred Heart University (USC)-
Autor(es): dc.creatorMomesso, Gustavo Antonio Correa [UNESP]-
Autor(es): dc.creatorLemos, Cleidiel Aparecido Araújo [UNESP]-
Autor(es): dc.creatorSantiago-Júnior, Joel Ferreira-
Autor(es): dc.creatorFaverani, Leonardo Perez [UNESP]-
Autor(es): dc.creatorPellizzer, Eduardo Piza [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:33:53Z-
Data de disponibilização: dc.date.available2022-02-22T00:33:53Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10006-020-00831-0-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201569-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201569-
Descrição: dc.descriptionPurpose: The aim of this study was to perform a systematic review and meta-analysis to evaluate the efficacy of laser therapy on medication-related osteonecrosis of the jaw (MRONJ) treatment. Methods: This study followed PRISMA standards, and an electronic search was performed on the PubMed/MEDLINE, Scopus, and Cochrane databases. Eighty-nine articles were found. After reading the manuscripts, 15 articles remained for the review. Three of them were selected for meta-analysis. Results: Female gender was predominant (72.5%), and mean age was 66.5 years. Follow-up varied between 3 and 80 months, and the most used bisphosphonate was zoledronic acid (71.6%). Stage II of MRONJ was the most prevalent (68.9%), and the mandible was the most affected site (64.5%). Qualitative data showed that treatment with laser surgery (Er:YAG) was most effective regarding complete healing of the lesion (90%) compared with other treatments. Meta-analysis data showed that low-level laser therapy (LLLT) was more effective than medical treatment (P = 0.006), and surgical treatment was more effective than LLLT (P = 0.008). Conclusion: Laser surgery was significantly superior to LLLT (p < 0.00001). Therefore, laser surgical therapy seems to be a great management strategy for MRONJ treatment from stage II. LLLT was shown to improve conservative management in earlier MRONJ stages.-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Aracatuba Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Health Sciences Sacred Heart University (USC)-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Aracatuba Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics School of Dentistry São Paulo State University (UNESP)-
Formato: dc.format133-144-
Idioma: dc.languageen-
Relação: dc.relationOral and Maxillofacial Surgery-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBisphosphonate-
Palavras-chave: dc.subjectLaser therapy-
Palavras-chave: dc.subjectLow-level laser therapy-
Palavras-chave: dc.subjectMedication-associated osteonecrosis of the jaw-
Título: dc.titleLaser surgery in management of medication-related osteonecrosis of the jaws: a meta-analysis-
Aparece nas coleções:Repositório Institucional - Unesp

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