In Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorUniversity of Saskatchewan-
Autor(es): dc.creatorPellissari, Claudia Viviane Guimarães [UNESP]-
Autor(es): dc.creatorVergani, Carlos Eduardo [UNESP]-
Autor(es): dc.creatorLongo, Elson-
Autor(es): dc.creatorPavarina, Ana Claudia [UNESP]-
Autor(es): dc.creatorSanitá, Paula Volpato [UNESP]-
Autor(es): dc.creatorSiqueira, Walter Luiz-
Autor(es): dc.creatorJorge, Janaina Habib [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:33:51Z-
Data de disponibilização: dc.date.available2022-02-22T00:33:51Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1155/2020/2971827-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201555-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201555-
Descrição: dc.descriptionPurpose. This study evaluated the cytotoxicity of antimicrobial silver tungstate (Ag2WO4) or silver molybdate (Ag2MoO4) microcrystals coating biomaterials. Materials and Methods. The coating procedure was performed onto titanium, zirconia, and acrylic resin specimens. Eluates of the coated specimens were obtained, which were used for cytotoxicity analyses, including Alamar Blue, MTT, and CytoTox-ONE tests. Data were analyzed using two-way ANOVA, followed by the Tukey test (α = 0.05). The results of each experimental group were also compared to those of the control of living cells, taken as 100% cell viability. Results. In general, it was observed that the percentage of living cells from all biomaterials coated with both microcrystals was statistically different compared to the ones from the uncoated sample groups, except for the results from MTT of specimens of Ti coated with α-Ag2MoO4. All uncoated biomaterials were classified as noncytotoxic by the three assays used in the present study. It was observed that the microcrystals in solution were strongly cytotoxic, with death of almost 100% of cells, from the analysis of the results of the Alamar Blue assay. Conclusion. The most biomaterials coated with both microcrystals showed some degree of cytotoxicity in the different assays. The results described herein should be seen as an alert to the use of microcrystals, which can expose patients to health risks.-
Descrição: dc.descriptionAraraquara Dental School São Paulo State University (UNESP)-
Descrição: dc.descriptionFederal University of São Carlos (UFSCar)-
Descrição: dc.descriptionUniversity of Saskatchewan-
Descrição: dc.descriptionAraraquara Dental School São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Nanomaterials-
???dc.source???: dc.sourceScopus-
Título: dc.titleIn Vitro Toxic Effect of Biomaterials Coated with Silver Tungstate or Silver Molybdate Microcrystals-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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