Do mineral and corn oil serve as potential endocrine disruptors in the gerbil prostate?

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorCentral-West Campus-
Autor(es): dc.creatorGuerra, Luiz Henrique Alves [UNESP]-
Autor(es): dc.creatorTamarindo, Guilherme Henrique-
Autor(es): dc.creatorde Campos, Silvana Gisele Pegorin-
Autor(es): dc.creatorTaboga, Sebastião Roberto [UNESP]-
Autor(es): dc.creatorVilamaior, Patricia Simone Leite [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:32:54Z-
Data de disponibilização: dc.date.available2022-02-22T00:32:54Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.reprotox.2019.09.004-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201206-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201206-
Descrição: dc.descriptionVegetable oils are frequently used as a vehicle in the administration of lipophilic drugs in animal tests. However, the composition of these oils may interfere with the results. One alternative to reduce this potential bias is the use of mineral oil, which is not supposed to interfere in the physiology of experimental models, since this oil is considered to be innocous. The present study shows for the first time the effects of the oral administration of corn and mineral on the prostate, demonstrating their interference in homeostasis and revealing their potential to act as endocrine disruptors. Mineral oil treatment increased the expression of AR and ERα and serum estradiol concentrations, while corn oil increased the expression of positive cells for both types of estrogen receptors. The variation in the expression of these hormone receptors resulted in morphological changes in the prostate.-
Descrição: dc.descriptionDepartment of Biology Institute of Biosciences Humanities and Exact Sciences São Paulo State University – UNESP-
Descrição: dc.descriptionDepartment of Functional and Structural Biology Institute of Biology University of Campinas – UNICAMP-
Descrição: dc.descriptionFederal University of São João Del Rei Central-West Campus-
Descrição: dc.descriptionDepartment of Biology Institute of Biosciences Humanities and Exact Sciences São Paulo State University – UNESP-
Formato: dc.format141-149-
Idioma: dc.languageen-
Relação: dc.relationReproductive Toxicology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCorn oil-
Palavras-chave: dc.subjectGerbil-
Palavras-chave: dc.subjectMineral oil-
Palavras-chave: dc.subjectProstate-
Palavras-chave: dc.subjectVehicle-
Título: dc.titleDo mineral and corn oil serve as potential endocrine disruptors in the gerbil prostate?-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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