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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.contributor | Irmandade da Santa Casa de Misericórdia de São Paulo | - |
Autor(es): dc.contributor | Faculty of Medical Sciences of Santa Casa de São Paulo | - |
Autor(es): dc.creator | da Cunha, Eliana Tomomi Shimabukuro [UNESP] | - |
Autor(es): dc.creator | Figueiredo-Godoi, Lívia Mara Alves [UNESP] | - |
Autor(es): dc.creator | Santos, Diogo Haddad | - |
Autor(es): dc.creator | Carneiro, Rafael Paterno Castello Dias | - |
Autor(es): dc.creator | do Olival, Guilherme Sciascia | - |
Autor(es): dc.creator | de Barros, Patrícia Pimentel [UNESP] | - |
Autor(es): dc.creator | Narimatsu, Keila | - |
Autor(es): dc.creator | Tilbery, Charles Peter | - |
Autor(es): dc.creator | Junqueira, Juliana Campos [UNESP] | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:32:46Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:32:46Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2019-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1007/s11046-020-00486-1 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/201159 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/201159 | - |
Descrição: dc.description | Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating autoimmune disease that affects the central nervous system. Since immune system plays a key role in this disease, patients with MS can present higher risk of infections. Purpose: This study aimed to investigate the prevalence of Candida spp. in the oral cavity of MS patients in relation to a control group Methods: In total, 100 individuals were selected: 55 diagnosed with MS and 45 healthy individuals (control group). Saliva samples were collected and seeded in culture media selecting for Candida. Following an incubation period of 48 h, colony-forming units (CFU mL−1) were counted and colonies were isolated for Candida species identification by multiplex PCR. The results were analysed by chi-squared and Mann–Whitney U statistical tests considering a significance level of 5%. Results: Candida spp. were confirmed in the oral cavity of 50.09% patients in the MS group and 35.55% individuals in the control group. In individuals positive for the growth of Candida spp., the median values of Candida colonies were 220 CFU mL−1 for the MS group and 120 CFU mL−1 for the control group. However, no statistically significant differences were observed between groups for both prevalence and CFU mL−1 count. Of the Candida species identified, 73.91% were C. albicans, 21.73% C. glabrata, 2.17% C. tropicalis, and 2.17% C. krusei. Conclusions: The colonization of Candida spp. in the oral cavity of individuals with multiple sclerosis was higher than in the control group; however these findings were not proven to be statistically significant. | - |
Descrição: dc.description | Department of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University (UNESP), Francisco José Longo 777, São Dimas | - |
Descrição: dc.description | Irmandade da Santa Casa de Misericórdia de São Paulo | - |
Descrição: dc.description | Department of Neurology Faculty of Medical Sciences of Santa Casa de São Paulo | - |
Descrição: dc.description | Department of Biosciences and Oral Diagnosis Institute of Science and Technology São Paulo State University (UNESP), Francisco José Longo 777, São Dimas | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Mycopathologia | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Autoimmune disease | - |
Palavras-chave: dc.subject | Candida | - |
Palavras-chave: dc.subject | Candida albicans | - |
Palavras-chave: dc.subject | Demyelinating disease | - |
Palavras-chave: dc.subject | Microbiota | - |
Palavras-chave: dc.subject | Multiple sclerosis | - |
Título: dc.title | Oral Colonization by Candida Species in Patients with Multiple Sclerosis | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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