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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade de São Paulo (USP) | - |
Autor(es): dc.contributor | Universidade Estadual Paulista (Unesp) | - |
Autor(es): dc.creator | Braga, Aline Silva | - |
Autor(es): dc.creator | Simas, Leticia Lobo de Melo | - |
Autor(es): dc.creator | Pires, Juliana Gonçalves | - |
Autor(es): dc.creator | Souza, Beatriz Martines | - |
Autor(es): dc.creator | de Melo, Fernanda Pereira de Souza Rosa [UNESP] | - |
Autor(es): dc.creator | Saldanha, Luiz Leonardo [UNESP] | - |
Autor(es): dc.creator | Dokkedal, Anne Ligia [UNESP] | - |
Autor(es): dc.creator | Magalhães, Ana Carolina | - |
Data de aceite: dc.date.accessioned | 2022-02-22T00:32:43Z | - |
Data de disponibilização: dc.date.available | 2022-02-22T00:32:43Z | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-12-11 | - |
Data de envio: dc.date.issued | 2020-08-01 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.1016/j.jdent.2020.103415 | - |
Fonte completa do material: dc.identifier | http://hdl.handle.net/11449/201141 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/201141 | - |
Descrição: dc.description | Objective: This study evaluated the antibiofilm and anti-caries effects of an experimental mouth rinse containing aqueous extract of Matricaria chamomilla L. Methods: Microcosm biofilm was produced on bovine enamel, from pooled human saliva mixed with McBain saliva, under 0.2 % sucrose exposure, for 5 days. The biofilm was daily treated using (1 mL/1 min): Vochysia tucanorum Mart. (2.5 mg/mL); Myrcia bella Cambess. (1.25 mg/mL); Matricaria chamomilla L. (20 mg/mL); Malva sylvestris (Malvatricin® Plus–Daudt); 0.12 % Chlorhexidine (PerioGard®-Palmolive, Positive control) and PBS (Negative control). The % dead bacteria, biofilm thickness, EPS biovolume, lactic acid concentration, the CFU counting (total microorganisms, Lactobacillus sp., total streptococci and Streptococcus mutans/S. sobrinus) were determined. Enamel demineralization was measured by TMR. Results: All mouth rinses induced bacterial death compared to PBS (p < 0.0001). The biofilm thickness varied from 12 ± 2 μm (chlorhexidine) to 18 ± 2 μm (V. tucanorum) (ANOVA/Tukey, p < 0.0001). The EPS biovolume varied from 7(4)% (chlorhexidine) to 30(20)% (PBS) (Kruskal-Wallis/Dunn, p < 0.0001). The lactic acid production was reduced by M. sylvestris (1.1 ± 0.2 g/L) and chlorhexidine (0.6 ± 0.2 g/L) compared to PBS (2.6 ± 1.3 g/L) (ANOVA, p < 0.0001). Malva sylvestris and chlorhexidine showed significant low CFU for total microorganisms, Lactobacillus sp. and total streptococci. Only chlorhexidine significantly reduced S. mutans/S. sobrinus. CFUs for total streptococci and Lactobacillus sp, were also significantly reduced by M. chamomilla L. Malva sylvestris (63.4 % of mineral loss reduction), chlorhexidine (47.4 %) and M. chamomilla L. (39.4 %) significantly reduced enamel demineralization compared to PBS (ANOVA/Tukey, p < 0.0001). Conclusion: M. chamomilla L. has lower antibiofilm action, but comparable anti-caries effect to those found for chlorhexidine, under this model. Clinical relevance: This study shows that the antibiofilm and anti-caries potential may vary between the commercial and experimental mouth rinses containing natural agents, with promising results for those containing Matricaria chamomilla L. and Malva Sylvestris. | - |
Descrição: dc.description | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) | - |
Descrição: dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | - |
Descrição: dc.description | Department of Biological Sciences Bauru School of Dentistry University of São Paulo | - |
Descrição: dc.description | Department of Biological Sciences School of Science The São Paulo State University (UNESP) | - |
Descrição: dc.description | Department of Biological Sciences School of Science The São Paulo State University (UNESP) | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Journal of Dentistry | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | Dental caries | - |
Palavras-chave: dc.subject | Enamel | - |
Palavras-chave: dc.subject | Microcosm biofilm | - |
Palavras-chave: dc.subject | Mouth wash | - |
Palavras-chave: dc.subject | Natural agents | - |
Título: dc.title | Antibiofilm and anti-caries effects of an experimental mouth rinse containing Matricaria chamomilla L. extract under microcosm biofilm on enamel | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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