Uncovering Sub-Structure and Genomic Profiles in Across-Countries Subpopulations of Angus Cattle

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversity of Alberta-
Autor(es): dc.contributorAgriculture and Agri-Food Canada-
Autor(es): dc.contributorEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)-
Autor(es): dc.contributorCSIRO Agriculture & Food-
Autor(es): dc.contributorNational Council for Science and Technological Development-
Autor(es): dc.contributorUniversity of Guelph-
Autor(es): dc.creatorCardoso, Diercles Francisco [UNESP]-
Autor(es): dc.creatorFernandes Júnior, Gerardo Alves [UNESP]-
Autor(es): dc.creatorScalez, Daiane Cristina Becker [UNESP]-
Autor(es): dc.creatorAlves, Anderson Antonio Carvalho [UNESP]-
Autor(es): dc.creatorMagalhães, Ana Fabrícia Braga [UNESP]-
Autor(es): dc.creatorBresolin, Tiago [UNESP]-
Autor(es): dc.creatorVentura, Ricardo Vieira-
Autor(es): dc.creatorLi, Changxi-
Autor(es): dc.creatorde Sena Oliveira, Márcia Cristina-
Autor(es): dc.creatorPorto-Neto, Laercio Ribeiro-
Autor(es): dc.creatorCarvalheiro, Roberto [UNESP]-
Autor(es): dc.creatorde Oliveira, Henrique Nunes [UNESP]-
Autor(es): dc.creatorTonhati, Humberto [UNESP]-
Autor(es): dc.creatorAlbuquerque, Lucia Galvão [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:32:40Z-
Data de disponibilização: dc.date.available2022-02-22T00:32:40Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-020-65565-1-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201132-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201132-
Descrição: dc.descriptionHighlighting genomic profiles for geographically distinct subpopulations of the same breed may provide insights into adaptation mechanisms to different environments, reveal genomic regions divergently selected, and offer initial guidance to joint genomic analysis. Here, we characterized similarities and differences between the genomic patterns of Angus subpopulations, born and raised in Canada (N = 382) and Brazil (N = 566). Furthermore, we systematically scanned for selection signatures based on the detection of autozygosity islands common between the two subpopulations, and signals of divergent selection, via FST and varLD tests. The principal component analysis revealed a sub-structure with a close connection between the two subpopulations. The averages of genomic relationships, inbreeding coefficients, and linkage disequilibrium at varying genomic distances were rather similar across them, suggesting non-accentuated differences in overall genomic diversity. Autozygosity islands revealed selection signatures common to both subpopulations at chromosomes 13 (63.77–65.25 Mb) and 14 (22.81–23.57 Mb), which are notably known regions affecting growth traits. Nevertheless, further autozygosity islands along with FST and varLD tests unravel particular sites with accentuated population subdivision at BTAs 7 and 18 overlapping with known QTL and candidate genes of reproductive performance, thermoregulation, and resistance to infectious diseases. Our findings indicate overall genomic similarity between Angus subpopulations, with noticeable signals of divergent selection in genomic regions associated with the adaptation in different environments.-
Descrição: dc.descriptionDepartment of Animal Science School of Agricultural and Veterinarian Science São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Animal Nutrition and Production School of Veterinary Medicine and Animal Science (FMVZ) University of Sao Paulo (USP)-
Descrição: dc.descriptionDepartment of Agricultural Food and Nutritional Science Faculty of Agricultural Life & Environmental Sciences University of Alberta-
Descrição: dc.descriptionLacombe Research and Development Centre Agriculture and Agri-Food Canada-
Descrição: dc.descriptionEmbrapa Pecuária Sudeste-
Descrição: dc.descriptionCSIRO Agriculture & Food, 306 Carmody Rd., St. Lucia-
Descrição: dc.descriptionNational Council for Science and Technological Development-
Descrição: dc.descriptionCentre for Genetic Improvement of Livestock Department of Animal Biosciences University of Guelph-
Descrição: dc.descriptionDepartment of Animal Science School of Agricultural and Veterinarian Science São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleUncovering Sub-Structure and Genomic Profiles in Across-Countries Subpopulations of Angus Cattle-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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