Phytochemical, metabolic profiling and antiparasitic potential from Inga semialata leaves (Fabaceae)

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Autor(es): dc.contributorUniversidade Estadual Paulista (Unesp)-
Autor(es): dc.contributorFederal Institute of Maranhão-
Autor(es): dc.creatorLima, Nerilson M. [UNESP]-
Autor(es): dc.creatorde Marqui, Sara R. [UNESP]-
Autor(es): dc.creatorAndrade, Teresinha de Jesus A. S.-
Autor(es): dc.creatorSilva, Dulce H. S. [UNESP]-
Data de aceite: dc.date.accessioned2022-02-22T00:32:22Z-
Data de disponibilização: dc.date.available2022-02-22T00:32:22Z-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2020-12-11-
Data de envio: dc.date.issued2019-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/14786419.2020.1817918-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/201025-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/201025-
Descrição: dc.descriptionNatural Products phytochemical provide a rich source for therapeutic discovery and has led to the development of many drugs. Thus, the aim of this study was to obtaining a metabolic profiling from ethanol extract of Inga semialata leaves (EEIS) selected by bioassay antimalarial and nematostatic and identify metabolites in mixture by co-injection experiments and NMR spectroscopy. The chemical composition of this species indicated a wide variety of aromatic acids (vanillic acid, 3,4,5-trimethoxy benzoic acid, gallic acid, methyl gallate, p-coumaric acid and ferulic acid), flavonoids (quercetin, myricetin-3-O-rhamnoside and myricetin-3-O-(2-O-galloyl)-α-rhamnopyranoside), triterpenes (lupeol, α-amyrin, friedelin and oleanolic acid) and the 2-hydroxyethyl-dodecanoate. The antimalarial assay showed that the I. semialatan-hexane fraction presented higher inhibition percentage than the Chloroquine standard and may be considered a potential source of compounds with antimalarial activity while the EEIS and its fractions showed nematostatic potential below 17% in the assay of nematostatic evaluation against the parasite Meloidogyne incognita.-
Descrição: dc.descriptionDepartment of Organic Chemistry Institute of Chemistry Nucleus of Bioassays Biosynthesis and Ecophysiology of Natural Products (NuBBE) São Paulo State University UNESP-
Descrição: dc.descriptionNucleus of Applied Research to Sciences (NIAC) Federal Institute of Maranhão-
Descrição: dc.descriptionDepartment of Organic Chemistry Institute of Chemistry Nucleus of Bioassays Biosynthesis and Ecophysiology of Natural Products (NuBBE) São Paulo State University UNESP-
Idioma: dc.languageen-
Relação: dc.relationNatural Product Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectantimalarial-
Palavras-chave: dc.subjectaromatic acids-
Palavras-chave: dc.subjectflavonoids-
Palavras-chave: dc.subjectInga semialata-
Palavras-chave: dc.subjectnematostatic-
Palavras-chave: dc.subjecttriterpenes-
Título: dc.titlePhytochemical, metabolic profiling and antiparasitic potential from Inga semialata leaves (Fabaceae)-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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